메뉴 건너뛰기




Volumn 23, Issue 3, 2016, Pages 213-218

Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; EPITOPE; POLYPEPTIDE; ANTHRAX TOXIN; ANTISERUM; BACTERIAL ANTIGEN; BACTERIAL TOXIN; BACTERIUM ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

EID: 84962549562     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00611-15     Document Type: Article
Times cited : (19)

References (28)
  • 2
    • 80052155168 scopus 로고    scopus 로고
    • Monoclonal antibody therapies against anthrax
    • Basel
    • Chen Z, Moayeri M, Purcell R. 2011. Monoclonal antibody therapies against anthrax. Toxins (Basel) 3:1004-1019. http://dx.doi.org/10.3390/toxins3081004.
    • (2011) Toxins , vol.3 , pp. 1004-1019
    • Chen, Z.1    Moayeri, M.2    Purcell, R.3
  • 4
    • 84878935042 scopus 로고    scopus 로고
    • Nanobodies: Natural single-domain antibodies
    • Muyldermans S. 2013. Nanobodies: Natural single-domain antibodies. Annu Rev Biochem 82:775-797. http://dx.doi.org/10.1146/annurev-biochem-063011-092449.
    • (2013) Annu Rev Biochem , vol.82 , pp. 775-797
    • Muyldermans, S.1
  • 5
  • 6
    • 84924787113 scopus 로고    scopus 로고
    • A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model
    • Moayeri M, Leysath CE, Tremblay JM, Vrentas C, Crown D, Leppla SH, Shoemaker CB. 2015. A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model. J Biol Chem 290:6584-6595. http://dx.doi.org/10.1074/jbc.M114.627943.
    • (2015) J Biol Chem , vol.290 , pp. 6584-6595
    • Moayeri, M.1    Leysath, C.E.2    Tremblay, J.M.3    Vrentas, C.4    Crown, D.5    Leppla, S.H.6    Shoemaker, C.B.7
  • 7
    • 84919484445 scopus 로고    scopus 로고
    • Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein
    • Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB. 2014. Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein. PLoS One 9:e106422. http://dx.doi.org/10.1371/journal.pone.0106422.
    • (2014) PLoS One , vol.9 , pp. e106422
    • Mukherjee, J.1    Dmitriev, I.2    Debatis, M.3    Tremblay, J.M.4    Beamer, G.5    Kashentseva, E.A.6    Curiel, D.T.7    Shoemaker, C.B.8
  • 12
    • 84890918372 scopus 로고    scopus 로고
    • Stepwise engineering of heterodimeric single domain camelidVHHantibodies that passively protect mice from ricin toxin
    • Vance DJ, Tremblay JM, Mantis NJ, Shoemaker CB. 2013. Stepwise engineering of heterodimeric single domain camelidVHHantibodies that passively protect mice from ricin toxin. J Biol Chem 288:36538-36547. http://dx.doi.org/10.1074/jbc.M113.519207.
    • (2013) J Biol Chem , vol.288 , pp. 36538-36547
    • Vance, D.J.1    Tremblay, J.M.2    Mantis, N.J.3    Shoemaker, C.B.4
  • 13
    • 37549040584 scopus 로고    scopus 로고
    • Rapid/sustained antianthrax passive immunity mediated by co-administration of Ad/AAV
    • De BP, Hackett NR, Crystal RG, Boyer JL. 2008. Rapid/sustained antianthrax passive immunity mediated by co-administration of Ad/AAV. Mol Ther 16:203-209. http://dx.doi.org/10.1038/sj.mt.6300344.
    • (2008) Mol Ther , vol.16 , pp. 203-209
    • De BP1    Hackett, N.R.2    Crystal, R.G.3    Boyer, J.L.4
  • 14
    • 63149166807 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge
    • Sofer-Podesta C, Ang J, Hackett NR, Senina S, Perlin D, Crystal RG, Boyer JL. 2009. Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge. Infect Immun 77:1561-1568. http://dx.doi.org/10.1128/IAI.00856-08.
    • (2009) Infect Immun , vol.77 , pp. 1561-1568
    • Sofer-Podesta, C.1    Ang, J.2    Hackett, N.R.3    Senina, S.4    Perlin, D.5    Crystal, R.G.6    Boyer, J.L.7
  • 16
    • 84936935341 scopus 로고    scopus 로고
    • Engineering humoral immunity as prophylaxis or therapy
    • Deal CE, Balazs AB. 2015. Engineering humoral immunity as prophylaxis or therapy. Curr Opin Immunol 35:113-122. http://dx.doi.org/10.1016/j.coi.2015.06.014.
    • (2015) Curr Opin Immunol , vol.35 , pp. 113-122
    • Deal, C.E.1    Balazs, A.B.2
  • 17
    • 84921327276 scopus 로고    scopus 로고
    • In situ production of therapeutic monoclonal antibodies
    • Suscovich TJ, Alter G. 2015. In situ production of therapeutic monoclonal antibodies. Expert Rev Vaccines 14:205-219. http://dx.doi.org/10.1586/14760584.2015.1001375.
    • (2015) Expert Rev Vaccines , vol.14 , pp. 205-219
    • Suscovich, T.J.1    Alter, G.2
  • 18
    • 0034049623 scopus 로고    scopus 로고
    • Optimized production and purification of Bacillus anthracis lethal factor
    • Park S, Leppla SH. 2000. Optimized production and purification of Bacillus anthracis lethal factor. Protein Expr Purif 18:293-302. http://dx.doi.org/10.1006/prep.2000.1208.
    • (2000) Protein Expr Purif , vol.18 , pp. 293-302
    • Park, S.1    Leppla, S.H.2
  • 19
  • 21
    • 84946944111 scopus 로고    scopus 로고
    • Mechanisms of ricin toxin neutralization revealed through engineered homodimeric and heterodimeric camelid antibodies
    • Herrera C, Tremblay JM, Shoemaker CB, Mantis NJ. 2015. Mechanisms of ricin toxin neutralization revealed through engineered homodimeric and heterodimeric camelid antibodies. J Biol Chem 290:27880-27889. http://dx.doi.org/10.1074/jbc.M115.658070.
    • (2015) J Biol Chem , vol.290 , pp. 27880-27889
    • Herrera, C.1    Tremblay, J.M.2    Shoemaker, C.B.3    Mantis, N.J.4
  • 22
    • 78651258397 scopus 로고    scopus 로고
    • Inflammasome sensor Nlrp1bdependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment
    • Moayeri M, Crown D, Newman ZL, Okugawa S, Eckhaus M, Cataisson C, Liu S, Sastalla I, Leppla SH. 2010. Inflammasome sensor Nlrp1bdependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment. PLoS Pathog 6:e1001222. http://dx.doi.org/10.1371/journal.ppat.1001222.
    • (2010) PLoS Pathog , vol.6 , pp. e1001222
    • Moayeri, M.1    Crown, D.2    Newman, Z.L.3    Okugawa, S.4    Eckhaus, M.5    Cataisson, C.6    Liu, S.7    Sastalla, I.8    Leppla, S.H.9
  • 23
    • 0034254715 scopus 로고    scopus 로고
    • Soluble CD8 attenuates cytotoxic T cell responses against replication-defective adenovirus affording transprotection of transgenes in vivo
    • Peng Y, Falck-Pedersen E, Elkon KB. 2000. Soluble CD8 attenuates cytotoxic T cell responses against replication-defective adenovirus affording transprotection of transgenes in vivo. J Immunol 165:1470-1478. http://dx.doi.org/10.4049/jimmunol.165.3.1470.
    • (2000) J Immunol , vol.165 , pp. 1470-1478
    • Peng, Y.1    Falck-Pedersen, E.2    Elkon, K.B.3
  • 24
    • 0035027216 scopus 로고    scopus 로고
    • Variation in adenovirus transgene expression between BALB/c and C57BL/6 mice is associated with differences in interleukin-12 and gamma interferon production and NK cell activation
    • Peng Y, Falck-Pedersen E, Elkon KB. 2001. Variation in adenovirus transgene expression between BALB/c and C57BL/6 mice is associated with differences in interleukin-12 and gamma interferon production and NK cell activation. J Virol 75:4540-4550. http://dx.doi.org/10.1128/JVI.75.10.4540-4550.2001.
    • (2001) J Virol , vol.75 , pp. 4540-4550
    • Peng, Y.1    Falck-Pedersen, E.2    Elkon, K.B.3
  • 26
    • 79953300992 scopus 로고    scopus 로고
    • Implications of the innate immune response to adenovirus and adenoviral vectors
    • Gregory SM, Nazir SA, Metcalf JP. 2011. Implications of the innate immune response to adenovirus and adenoviral vectors. Future Virol 6:357-374. http://dx.doi.org/10.2217/fvl.11.6.
    • (2011) Future Virol , vol.6 , pp. 357-374
    • Gregory, S.M.1    Nazir, S.A.2    Metcalf, J.P.3
  • 27
    • 11144248909 scopus 로고    scopus 로고
    • The innate immune response to adenovirus vectors
    • Muruve DA. 2004. The innate immune response to adenovirus vectors. Hum Gene Ther 15:1157-1166. http://dx.doi.org/10.1089/hum.2004.15.1157.
    • (2004) Hum Gene Ther , vol.15 , pp. 1157-1166
    • Muruve, D.A.1
  • 28
    • 84880220595 scopus 로고    scopus 로고
    • A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism
    • Alberti MO, Deshane JS, Chaplin DD, Pereboeva L, Curiel DT, Roth JC. 2013. A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism. Gene Ther 20:733-741. http://dx.doi.org/10.1038/gt.2012.91.
    • (2013) Gene Ther , vol.20 , pp. 733-741
    • Alberti, M.O.1    Deshane, J.S.2    Chaplin, D.D.3    Pereboeva, L.4    Curiel, D.T.5    Roth, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.