Quillaja brasiliensis saponins induce robust humoral and cellular responses in a bovine viral diarrhea virus vaccine in mice

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 45, Issue , 2016, Pages 1-8

  Cibulski, Samuel Paulo ^a,b   Silveira, Fernando ^c   Mourglia Ettlin, Gustavo ^d   Teixeira, Thais Fumaco ^a,b   dos Santos, Helton Fernandes ^a,b   Yendo, Anna Carolina ^b   de Costa, Fernanda ^b   Fett Neto, Arthur Germano ^b   Gosmann, Grace ^b   Roehe, Paulo Michel ^a,b  

^a Fepagro Saúde Animal Instituto de Pesquisas Veterinárias Desidério Finamor IPVDF   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Adjuvant; BVDV; Cellular immunity; Immune response; QB 90; Quillaja brasiliensis; Vaccine

Indexed keywords

ALUMINUM POTASSIUM SULFATE; BOVINE VIRAL DIARRHEA VIRUS VACCINE; FREUND ADJUVANT; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; PLANT EXTRACT; QUIL A; QUILLAJA BRASILIENSIS EXTRACT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOLOGICAL ADJUVANT; QUILLAJA SAPONIN; VIRUS ANTIBODY; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY DETECTION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOLYSIS; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; QUILLAJA; QUILLAJA BRASILIENSIS; SPLEEN CELL; ANIMAL; BLOOD; BOVINE; BOVINE VIRAL DIARRHEA VIRUS 1; CHEMISTRY; DELAYED HYPERSENSITIVITY; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; PLANT LEAF; SECRETION (PROCESS); TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; CATTLE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; DIARRHEA VIRUS 1, BOVINE VIRAL; HYPERSENSITIVITY, DELAYED; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNOGLOBULIN G; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE; PLANT EXTRACTS; PLANT LEAVES; QUILLAJA; QUILLAJA SAPONINS; TH1 CELLS; VIRAL VACCINES;

EID: 84962545649     PISSN: 01479571     EISSN: 18781667     Source Type: Journal    
DOI: 10.1016/j.cimid.2016.01.004     Document Type: Article

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