Mincle activation and the Syk/Card9 signaling axis are central to the development of autoimmune disease of the eye

Journal of Immunology

Volumn 196, Issue 7, 2016, Pages 3148-3158

  Lee, Ellen J ^a,b   Brown, Brieanna R ^a   Vance, Emily E ^a,b   Snow, Paige E ^a   Silver, Phyllis B ^c   Heinrichs, David ^a   Lin, Xin ^d   Iwakura, Yoichiro ^e   Wells, Christine A ^f   Caspi, Rachel R ^c   Rosenzweig, Holly L ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e TOKYO UNIVERSITY OF SCIENCE   (Japan)

^f UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE ASSOCIATED RECRUITMENT DOMAIN ADAPTOR 9; DECTIN 1; DECTIN 2; FREUND ADJUVANT; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; LECTIN RECEPTOR; MINCLE PROTEIN; PROTEIN KINASE SYK; UNCLASSIFIED DRUG; CALCITONIN RECEPTOR LIKE RECEPTOR; CARD9 PROTEIN, MOUSE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CLECSF8 PROTEIN, MOUSE; DECTIN-2, MOUSE; EYE PROTEIN; INTERSTITIAL RETINOL-BINDING PROTEIN; LECTIN; MEMBRANE PROTEIN; PROTEIN TYROSINE KINASE; RETINOL BINDING PROTEIN; SIGNAL PEPTIDE; SYK PROTEIN, HUMAN; SYK PROTEIN, MOUSE; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CARD9 GENE; CLINICAL FEATURE; EXPERIMENTAL AUTOIMMUNE UVEORETINITIS; EXPERIMENTAL UVEITIS; EYE INFLAMMATION; GENE DELETION; GENE EXPRESSION; GRANULOMA; IMMUNE RESPONSE; IMMUNOREGULATION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; RETINA INJURY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH17 CELL; UVEORETINITIS; VASCULITIS; ANIMAL; AUTOIMMUNE DISEASES; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; RETINA; T LYMPHOCYTE SUBPOPULATION; UVEITIS;

ANIMALS; AUTOIMMUNE DISEASES; CALCITONIN RECEPTOR-LIKE PROTEIN; CARD SIGNALING ADAPTOR PROTEINS; DISEASE MODELS, ANIMAL; EYE PROTEINS; GENE EXPRESSION; GENE EXPRESSION PROFILING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROTEIN-TYROSINE KINASES; RETINA; RETINOL-BINDING PROTEINS; SIGNAL TRANSDUCTION; SYK KINASE; T-LYMPHOCYTE SUBSETS; TH17 CELLS; TRANSCRIPTOME; UVEITIS;

EID: 84962494963     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502355     Document Type: Article

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