Contribution of MINCLE-SYK signaling to activation of primary human APCs by mycobacterial cord factor and the novel adjuvant TDB

Journal of Immunology

Volumn 195, Issue 5, 2015, Pages 2417-2428

  Ostrop, Jenny ^a   Jozefowski, Katrin ^a   Zimmermann, Stephanie ^b,c   Hofmann, Katharina ^a   Strasser, Erwin ^a   Lepenies, Bernd ^a,c,d   Lang, Roland ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADJUVANT; APC PROTEIN; B7 ANTIGEN; CARD9 PROTEIN; CD83 ANTIGEN; CD86 ANTIGEN; CORD FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LECTIN; MACROPHAGE C TYPE LECTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE SYK; SMALL INTERFERING RNA; TREHALOSE 6,6 DIBEHENATE; UNCLASSIFIED DRUG; CARD9 PROTEIN, HUMAN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CHEMOKINE; CLEC4D PROTEIN, HUMAN; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; IMMUNOLOGICAL ADJUVANT; PROTEIN BINDING; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; DENDRITIC CELL; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IMMUNOSTIMULATION; IN VITRO STUDY; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE; MACROPHAGE ACTIVATION; MCL GENE; MINCLE GENE; MONOCYTE; MOUSE; MYCOBACTERIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; CELL CULTURE; CHEMISTRY; FLOW CYTOMETRY; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BLOTTING, WESTERN; CARD SIGNALING ADAPTOR PROTEINS; CELLS, CULTURED; CHEMOKINES; CORD FACTORS; CYTOKINES; DENDRITIC CELLS; FLOW CYTOMETRY; GENE EXPRESSION; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MACROPHAGES; MICE, KNOCKOUT; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 84940118733     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500102     Document Type: Article

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