-
1
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
1:CAS:528:DC%2BD28XhtVyktbbO 17051205
-
Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 2006;443(7113):787-95.
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
2
-
-
79955646829
-
Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease
-
Pubmed Central PMCID: 2947925
-
Navarro A, Boveris A. Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease. Front Aging Neurosci. 2010;2. Pubmed Central PMCID: 2947925.
-
(2010)
Front Aging Neurosci
, vol.2
-
-
Navarro, A.1
Boveris, A.2
-
3
-
-
68649108355
-
Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis
-
1:CAS:528:DC%2BD1MXnsFygs74%3D 19059336 2867353 Pubmed Central PMCID: 2867353
-
Banerjee R, Starkov AA, Beal MF, Thomas B. Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis. Biochim Biophys Acta. 2009;1792(7):651-63. Pubmed Central PMCID: 2867353.
-
(2009)
Biochim Biophys Acta
, vol.1792
, Issue.7
, pp. 651-663
-
-
Banerjee, R.1
Starkov, A.A.2
Beal, M.F.3
Thomas, B.4
-
4
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
1:CAS:528:DC%2BD28XjvVGksbs%3D 16604074
-
Bender A, Krishnan KJ, Morris CM, Taylor GA, Reeve AK, Perry RH, et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat Genet. 2006;38(5):515-7.
-
(2006)
Nat Genet
, vol.38
, Issue.5
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
-
5
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
1:CAS:528:DC%2BD28XjvVGktr0%3D 16604072
-
Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet. 2006;38(5):518-20.
-
(2006)
Nat Genet
, vol.38
, Issue.5
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
6
-
-
0027750939
-
Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes
-
8293280
-
Benecke R, Strumper P, Weiss H. Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes. Brain. 1993;116(Pt 6):1451-63.
-
(1993)
Brain
, vol.116
, Issue.6
, pp. 1451-1463
-
-
Benecke, R.1
Strumper, P.2
Weiss, H.3
-
7
-
-
0027515694
-
Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson's disease
-
1:STN:280:DyaK2c%2FltVKisQ%3D%3D 8232939
-
Cardellach F, Marti MJ, Fernandez-Sola J, Marin C, Hoek JB, Tolosa E, et al. Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson's disease. Neurology. 1993;43(11):2258-62.
-
(1993)
Neurology
, vol.43
, Issue.11
, pp. 2258-2262
-
-
Cardellach, F.1
Marti, M.J.2
Fernandez-Sola, J.3
Marin, C.4
Hoek, J.B.5
Tolosa, E.6
-
8
-
-
0027971104
-
Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy
-
1:STN:280:DyaK2M%2FlsVWqtA%3D%3D 7964895
-
Blin O, Desnuelle C, Rascol O, Borg M, Peyro Saint Paul H, Azulay JP, et al. Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy. J Neurol Sci. 1994;125(1):95-101.
-
(1994)
J Neurol Sci
, vol.125
, Issue.1
, pp. 95-101
-
-
Blin, O.1
Desnuelle, C.2
Rascol, O.3
Borg, M.4
Peyro Saint Paul, H.5
Azulay, J.P.6
-
9
-
-
0025831821
-
Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease
-
1:STN:280:DyaK38%2FksVKiug%3D%3D 1658241
-
Bindoff LA, Birch-Machin MA, Cartlidge NE, Parker Jr WD, Turnbull DM. Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease. J Neurol Sci. 1991;104(2):203-8.
-
(1991)
J Neurol Sci
, vol.104
, Issue.2
, pp. 203-208
-
-
Bindoff, L.A.1
Birch-Machin, M.A.2
Cartlidge, N.E.3
Parker, W.D.4
Turnbull, D.M.5
-
10
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
1:CAS:528:DC%2BD1cXhsVOjtrjJ 19029340 2592826 Pubmed Central PMCID: 2592826, Epub 2008/11/26. eng
-
Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol. 2008;183(5):795-803. Pubmed Central PMCID: 2592826, Epub 2008/11/26. eng.
-
(2008)
J Cell Biol
, vol.183
, Issue.5
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
11
-
-
84922776083
-
PINK1/Parkin-mediated mitophagy in mammalian cells
-
1:CAS:528:DC%2BC2MXhtF2msrg%3D 25697963
-
Eiyama A, Okamoto K. PINK1/Parkin-mediated mitophagy in mammalian cells. Curr Opin Cell Biol. 2015;33:95-101.
-
(2015)
Curr Opin Cell Biol
, vol.33
, pp. 95-101
-
-
Eiyama, A.1
Okamoto, K.2
-
12
-
-
84864855869
-
Parkinson's disease, insulin resistance and novel agents of neuroprotection
-
22344583
-
Aviles-Olmos I, Limousin P, Lees A, Foltynie T. Parkinson's disease, insulin resistance and novel agents of neuroprotection. Brain. 2013;136(Pt 2):374-84.
-
(2013)
Brain
, vol.136
, Issue.2
, pp. 374-384
-
-
Aviles-Olmos, I.1
Limousin, P.2
Lees, A.3
Foltynie, T.4
-
13
-
-
84906306620
-
Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: Future therapeutic perspectives
-
1:CAS:528:DC%2BC2cXhtVanu7jL 24954676
-
Schapira AH, Olanow CW, Greenamyre JT, Bezard E. Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives. Lancet. 2014;384(9942):545-55.
-
(2014)
Lancet
, vol.384
, Issue.9942
, pp. 545-555
-
-
Schapira, A.H.1
Olanow, C.W.2
Greenamyre, J.T.3
Bezard, E.4
-
14
-
-
14844328611
-
Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha
-
1:CAS:528:DC%2BD2MXht1Omt70%3D
-
Puigserver P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. Int J Obes. 2005;29 Suppl 1:S5-9.
-
(2005)
Int J Obes
, vol.29
, Issue.1
, pp. S5-S9
-
-
Puigserver, P.1
-
15
-
-
84880960883
-
Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy
-
23794606 4550111
-
Morato L, Galino J, Ruiz M, Calingasan NY, Starkov AA, Dumont M, et al. Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. Brain. 2013;136(Pt 8):2432-43.
-
(2013)
Brain
, vol.136
, Issue.8
, pp. 2432-2443
-
-
Morato, L.1
Galino, J.2
Ruiz, M.3
Calingasan, N.Y.4
Starkov, A.A.5
Dumont, M.6
-
16
-
-
84962465835
-
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
-
Epub 2014/08/13. Eng
-
Yu Y, Li X, Blanchard J, Li Y, Iqbal K, Liu F, et al. Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice. J Neural Transm. 2014;13. Epub 2014/08/13. Eng.
-
(2014)
J Neural Transm
, vol.13
-
-
Yu, Y.1
Li, X.2
Blanchard, J.3
Li, Y.4
Iqbal, K.5
Liu, F.6
-
17
-
-
84870226700
-
PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice
-
1:CAS:528:DC%2BC38XhslOqtLvP 23197723
-
Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. J Neurosci. 2012;32(48):17321-31.
-
(2012)
J Neurosci
, vol.32
, Issue.48
, pp. 17321-17331
-
-
Yamanaka, M.1
Ishikawa, T.2
Griep, A.3
Axt, D.4
Kummer, M.P.5
Heneka, M.T.6
-
18
-
-
84864249514
-
Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease
-
1:CAS:528:DC%2BC38XhtFart7%2FL 22836247 3433721 Pubmed Central PMCID: 3433721
-
Mandrekar-Colucci S, Karlo JC, Landreth GE. Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease. J Neurosci. 2012;32(30):10117-28. Pubmed Central PMCID: 3433721.
-
(2012)
J Neurosci
, vol.32
, Issue.30
, pp. 10117-10128
-
-
Mandrekar-Colucci, S.1
Karlo, J.C.2
Landreth, G.E.3
-
19
-
-
79957858160
-
Protective effect of pioglitazone, a PPARgamma ligand, in a 3 nitropropionic acid model of Huntington's disease
-
1:CAS:528:DC%2BC3MXntFCrtr4%3D 21440606
-
Napolitano M, Costa L, Palermo R, Giovenco A, Vacca A, Gulino A. Protective effect of pioglitazone, a PPARgamma ligand, in a 3 nitropropionic acid model of Huntington's disease. Brain Res Bull. 2011;85(3-4):231-7.
-
(2011)
Brain Res Bull
, vol.85
, Issue.3-4
, pp. 231-237
-
-
Napolitano, M.1
Costa, L.2
Palermo, R.3
Giovenco, A.4
Vacca, A.5
Gulino, A.6
-
20
-
-
84908667745
-
Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine
-
Barbieroa JK, Santiagoa RM, Persikeb DS, da Silva Fernandesb MJ, Tonina FS, da Cunhaa C, et al. Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine. Behav Brain Res. 2014;274:390-9.
-
(2014)
Behav Brain Res
, vol.274
, pp. 390-399
-
-
Barbieroa, J.K.1
Santiagoa, R.M.2
Persikeb, D.S.3
Da Silva Fernandesb, M.J.4
Tonina, F.S.5
Da Cunhaa, C.6
-
21
-
-
42949100802
-
The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B
-
1:CAS:528:DC%2BD1cXltFOqs7k%3D 18332857 2438969 Pubmed Central PMCID: 2438969, Epub 2008/03/12. eng
-
Quinn LP, Crook B, Hows ME, Vidgeon-Hart M, Chapman H, Upton N, et al. The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B. Br J Pharmacol. 2008;154(1):226-33. Pubmed Central PMCID: 2438969, Epub 2008/03/12. eng.
-
(2008)
Br J Pharmacol
, vol.154
, Issue.1
, pp. 226-233
-
-
Quinn, L.P.1
Crook, B.2
Hows, M.E.3
Vidgeon-Hart, M.4
Chapman, H.5
Upton, N.6
-
22
-
-
79961103714
-
The PPAR-gamma agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
-
1:CAS:528:DC%2BC3MXhtFegsbfP 21819568 3166925 Pubmed Central PMCID: 3166925
-
Swanson CR, Joers V, Bondarenko V, Brunner K, Simmons HA, Ziegler TE, et al. The PPAR-gamma agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys. J Neuroinflammation. 2011;8:91. Pubmed Central PMCID: 3166925.
-
(2011)
J Neuroinflammation
, vol.8
, pp. 91
-
-
Swanson, C.R.1
Joers, V.2
Bondarenko, V.3
Brunner, K.4
Simmons, H.A.5
Ziegler, T.E.6
-
23
-
-
79960171961
-
Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease
-
1:CAS:528:DC%2BC3MXos1ygtrs%3D 21600965
-
Ulusoy GK, Celik T, Kayir H, Gursoy M, Isik AT, Uzbay TI. Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease. Brain Res Bull. 2011;85(6):380-4.
-
(2011)
Brain Res Bull
, vol.85
, Issue.6
, pp. 380-384
-
-
Ulusoy, G.K.1
Celik, T.2
Kayir, H.3
Gursoy, M.4
Isik, A.T.5
Uzbay, T.I.6
-
24
-
-
0028152645
-
Biosynthesis and functional role of haem O and haem A
-
1:CAS:528:DyaK2MXitFKgt7Y%3D 7885224 Epub 1994/11/01. eng
-
Mogi T, Saiki K, Anraku Y. Biosynthesis and functional role of haem O and haem A. Mol Microbiol. 1994;14(3):391-8. Epub 1994/11/01. eng.
-
(1994)
Mol Microbiol
, vol.14
, Issue.3
, pp. 391-398
-
-
Mogi, T.1
Saiki, K.2
Anraku, Y.3
-
25
-
-
24944447977
-
Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency
-
1:CAS:528:DC%2BD2MXpvFeqsro%3D 16103131 2778476 Pubmed Central PMCID: 2778476
-
Diaz F, Thomas CK, Garcia S, Hernandez D, Moraes CT. Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency. Hum Mol Genet. 2005;14(18):2737-48. Pubmed Central PMCID: 2778476.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.18
, pp. 2737-2748
-
-
Diaz, F.1
Thomas, C.K.2
Garcia, S.3
Hernandez, D.4
Moraes, C.T.5
-
26
-
-
33748637350
-
Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus
-
1:CAS:528:DC%2BD28XpslGks7w%3D 16865686
-
Backman CM, Malik N, Zhang Y, Shan L, Grinberg A, Hoffer BJ, et al. Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis. 2006;44(8):383-90.
-
(2006)
Genesis
, vol.44
, Issue.8
, pp. 383-390
-
-
Backman, C.M.1
Malik, N.2
Zhang, Y.3
Shan, L.4
Grinberg, A.5
Hoffer, B.J.6
-
27
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
1:CAS:528:DC%2BD3sXnsFait7o%3D 12971891
-
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron. 2003;39(6):889-909.
-
(2003)
Neuron
, vol.39
, Issue.6
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
28
-
-
82555174637
-
Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease
-
1:CAS:528:DC%2BC38Xks1emsb8%3D 22131425 3361134 Pubmed Central PMCID: 3361134
-
Pickrell AM, Pinto M, Hida A, Moraes CT. Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci. 2011;31(48):17649-58. Pubmed Central PMCID: 3361134.
-
(2011)
J Neurosci
, vol.31
, Issue.48
, pp. 17649-17658
-
-
Pickrell, A.M.1
Pinto, M.2
Hida, A.3
Moraes, C.T.4
-
29
-
-
84882827626
-
Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy
-
1:CAS:528:DC%2BC3sXkvFKhsw%3D%3D 23261681 3755107 Pubmed Central PMCID: 3755107, Epub 2012/12/25. eng
-
Noe N, Dillon L, Lellek V, Diaz F, Hida A, Moraes CT, et al. Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy. Mitochondrion. 2013;13(5):417-26. Pubmed Central PMCID: 3755107, Epub 2012/12/25. eng.
-
(2013)
Mitochondrion
, vol.13
, Issue.5
, pp. 417-426
-
-
Noe, N.1
Dillon, L.2
Lellek, V.3
Diaz, F.4
Hida, A.5
Moraes, C.T.6
-
30
-
-
84937634662
-
Mitochondrial Diseases Part III: Therapeutic interventions in mouse models of OXPHOS deficiencies
-
1:CAS:528:DC%2BC2MXitVCksrw%3D 25638392
-
Peralta S, Torraco A, Iommarini L, Diaz F. Mitochondrial Diseases Part III: Therapeutic interventions in mouse models of OXPHOS deficiencies. Mitochondrion. 2015;23:71-80.
-
(2015)
Mitochondrion
, vol.23
, pp. 71-80
-
-
Peralta, S.1
Torraco, A.2
Iommarini, L.3
Diaz, F.4
-
31
-
-
0031057599
-
Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys
-
1:CAS:528:DyaK2sXptlCmtA%3D%3D 9037440
-
Maeshiba Y, Kiyota Y, Yamashita K, Yoshimura Y, Motohashi M, Tanayama S. Disposition of the new antidiabetic agent pioglitazone in rats, dogs, and monkeys. Arzneimittelforschung. 1997;47(1):29-35.
-
(1997)
Arzneimittelforschung
, vol.47
, Issue.1
, pp. 29-35
-
-
Maeshiba, Y.1
Kiyota, Y.2
Yamashita, K.3
Yoshimura, Y.4
Motohashi, M.5
Tanayama, S.6
-
32
-
-
84868110583
-
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons
-
1:CAS:528:DC%2BC38XhsFOqsL%2FE 22914740 Epub 2012/08/24. eng
-
Lee S, Sterky FH, Mourier A, Terzioglu M, Cullheim S, Olson L, et al. Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet. 2012;21(22):4827-35. Epub 2012/08/24. eng.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.22
, pp. 4827-4835
-
-
Lee, S.1
Sterky, F.H.2
Mourier, A.3
Terzioglu, M.4
Cullheim, S.5
Olson, L.6
-
33
-
-
0034660063
-
Dopamine-deficient mice are hypersensitive to dopamine receptor agonists
-
1:CAS:528:DC%2BD3cXktVCktL4%3D 10844009
-
Kim DS, Szczypka MS, Palmiter RD. Dopamine-deficient mice are hypersensitive to dopamine receptor agonists. J Neurosci. 2000;20(12):4405-13.
-
(2000)
J Neurosci
, vol.20
, Issue.12
, pp. 4405-4413
-
-
Kim, D.S.1
Szczypka, M.S.2
Palmiter, R.D.3
-
34
-
-
84877949532
-
Modulating microglia activity with PPAR-gamma agonists: A promising therapy for Parkinson's disease?
-
1:CAS:528:DC%2BC3sXitlWq 22869006
-
Carta AR, Pisanu A. Modulating microglia activity with PPAR-gamma agonists: a promising therapy for Parkinson's disease? Neurotox Res. 2013;23(2):112-23.
-
(2013)
Neurotox Res
, vol.23
, Issue.2
, pp. 112-123
-
-
Carta, A.R.1
Pisanu, A.2
-
35
-
-
0035091767
-
The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety
-
1:CAS:528:DC%2BD3MXhvVCjtLw%3D 11238711 Epub 2001/03/10. eng
-
Przedborski S, Jackson-Lewis V, Naini AB, Jakowec M, Petzinger G, Miller R, et al. The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety. J Neurochem. 2001;76(5):1265-74. Epub 2001/03/10. eng.
-
(2001)
J Neurochem
, vol.76
, Issue.5
, pp. 1265-1274
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Naini, A.B.3
Jakowec, M.4
Petzinger, G.5
Miller, R.6
-
36
-
-
34347259269
-
Protocol for the MPTP mouse model of Parkinson's disease
-
1:CAS:528:DC%2BD2sXhtFGntb3N 17401348 Epub 2007/04/03. eng
-
Jackson-Lewis V, Przedborski S. Protocol for the MPTP mouse model of Parkinson's disease. Nat Protoc. 2007;2(1):141-51. Epub 2007/04/03. eng.
-
(2007)
Nat Protoc
, vol.2
, Issue.1
, pp. 141-151
-
-
Jackson-Lewis, V.1
Przedborski, S.2
-
37
-
-
80052533576
-
Animal models of Parkinson's disease: A source of novel treatments and clues to the cause of the disease
-
1:CAS:528:DC%2BC3MXhtlShtrbM 21486284 3229766 Pubmed Central PMCID: 3229766, Epub 2011/04/14. eng
-
Duty S, Jenner P. Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease. Br J Pharmacol. 2011;164(4):1357-91. Pubmed Central PMCID: 3229766, Epub 2011/04/14. eng.
-
(2011)
Br J Pharmacol
, vol.164
, Issue.4
, pp. 1357-1391
-
-
Duty, S.1
Jenner, P.2
-
38
-
-
77953666105
-
Genetic animal models of Parkinson's disease
-
1:CAS:528:DC%2BC3cXnvFaksb4%3D 20547124 2917798 Pubmed Central PMCID: 2917798, Epub 2010/06/16. eng
-
Dawson TM, Ko HS, Dawson VL. Genetic animal models of Parkinson's disease. Neuron. 2010;66(5):646-61. Pubmed Central PMCID: 2917798, Epub 2010/06/16. eng.
-
(2010)
Neuron
, vol.66
, Issue.5
, pp. 646-661
-
-
Dawson, T.M.1
Ko, H.S.2
Dawson, V.L.3
-
39
-
-
84941123145
-
Transgenic rodent models to study alpha-synuclein pathogenesis, with a focus on cognitive deficits
-
25218491
-
Hatami A, Chesselet MF. Transgenic rodent models to study alpha-synuclein pathogenesis, with a focus on cognitive deficits. Curr Top Behav Neurosci. 2015;22:303-30.
-
(2015)
Curr Top Behav Neurosci
, vol.22
, pp. 303-330
-
-
Hatami, A.1
Chesselet, M.F.2
-
40
-
-
84875597097
-
Mouse models of Parkinson's disease associated with mitochondrial dysfunction
-
1:CAS:528:DC%2BC38XhtlGqtLzO 22954895 3997253 Pubmed Central PMCID: 3997253, Epub 2012/09/08. eng
-
Pickrell AM, Pinto M, Moraes CT. Mouse models of Parkinson's disease associated with mitochondrial dysfunction. Mol Cell Neurosci. 2013;55:87-94. Pubmed Central PMCID: 3997253, Epub 2012/09/08. eng.
-
(2013)
Mol Cell Neurosci
, vol.55
, pp. 87-94
-
-
Pickrell, A.M.1
Pinto, M.2
Moraes, C.T.3
-
41
-
-
71849092169
-
The MitoPark Mouse - An animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons
-
20082987 Epub 2010/01/30. eng
-
Ekstrand MI, Galter D. The MitoPark Mouse - an animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons. Parkinsonism Relat Disord. 2009;15 Suppl 3:S185-8. Epub 2010/01/30. eng.
-
(2009)
Parkinsonism Relat Disord
, vol.15
, Issue.3
, pp. S185-S188
-
-
Ekstrand, M.I.1
Galter, D.2
-
42
-
-
84940467319
-
Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo
-
1:CAS:528:DC%2BC2MXpsFehtrc%3D 26070241
-
Kim HW, Choi WS, Sorscher N, Park HJ, Tronche F, Palmiter RD, et al. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo. Neurobiol Aging. 2015;36(9):2617-27.
-
(2015)
Neurobiol Aging
, vol.36
, Issue.9
, pp. 2617-2627
-
-
Kim, H.W.1
Choi, W.S.2
Sorscher, N.3
Park, H.J.4
Tronche, F.5
Palmiter, R.D.6
-
43
-
-
84886020232
-
Levodopa-induced dyskinesias in Parkinson's disease: Emerging treatments
-
24174877 3808152 Pubmed Central PMCID: 3808152
-
Bargiotas P, Konitsiotis S. Levodopa-induced dyskinesias in Parkinson's disease: emerging treatments. Neuropsychiatr Dis Treat. 2013;9:1605-17. Pubmed Central PMCID: 3808152.
-
(2013)
Neuropsychiatr Dis Treat
, vol.9
, pp. 1605-1617
-
-
Bargiotas, P.1
Konitsiotis, S.2
-
44
-
-
84902996320
-
Expression of peroxisome proliferator-activated receptor-gamma in the substantia nigra of hemiparkinsonian nonhuman primates
-
1:CAS:528:DC%2BC2cXlvVSmurg%3D 24620964 4254814
-
Swanson C, Emborg M. Expression of peroxisome proliferator-activated receptor-gamma in the substantia nigra of hemiparkinsonian nonhuman primates. Neurol Res. 2014;36(7):634-46.
-
(2014)
Neurol Res
, vol.36
, Issue.7
, pp. 634-646
-
-
Swanson, C.1
Emborg, M.2
-
45
-
-
50049118173
-
Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
-
1:CAS:528:DC%2BD1cXhtFeju77L 18762025 2613643 Pubmed Central PMCID: 2613643, Epub 2008/09/03. eng
-
Wenz T, Diaz F, Spiegelman BM, Moraes CT. Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab. 2008;8(3):249-56. Pubmed Central PMCID: 2613643, Epub 2008/09/03. eng.
-
(2008)
Cell Metab
, vol.8
, Issue.3
, pp. 249-256
-
-
Wenz, T.1
Diaz, F.2
Spiegelman, B.M.3
Moraes, C.T.4
-
46
-
-
34548494847
-
Drug insight: Effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders
-
1:CAS:528:DC%2BD2sXpvFWmuro%3D 17805244 Epub 2007/09/07. eng
-
Heneka MT, Landreth GE, Hull M. Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders. Nat Clin Pract Neurol. 2007;3(9):496-504. Epub 2007/09/07. eng.
-
(2007)
Nat Clin Pract Neurol
, vol.3
, Issue.9
, pp. 496-504
-
-
Heneka, M.T.1
Landreth, G.E.2
Hull, M.3
-
47
-
-
84937520622
-
Pioglitazone in early Parkinson's disease: A phase 2, multicentre, double-blind, randomised trial
-
Investigators NETiPDF-Z
-
Investigators NETiPDF-Z. Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial. Lancet Neurol. 2015;14(8):795-803.
-
(2015)
Lancet Neurol
, vol.14
, Issue.8
, pp. 795-803
-
-
-
48
-
-
84908667745
-
Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine
-
1:CAS:528:DC%2BC2cXhtlOrt7fN 25127682
-
Barbiero JK, Santiago RM, Persike DS, da Silva Fernandes MJ, Tonin FS, da Cunha C, et al. Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine. Behav Brain Res. 2014;274:390-9.
-
(2014)
Behav Brain Res
, vol.274
, pp. 390-399
-
-
Barbiero, J.K.1
Santiago, R.M.2
Persike, D.S.3
Da Silva Fernandes, M.J.4
Tonin, F.S.5
Da Cunha, C.6
-
49
-
-
84939208750
-
Insights into Neuroinflammation in Parkinson's Disease: From Biomarkers to Anti-Inflammatory Based Therapies
-
26295044 4532803 Pubmed Central PMCID: 4532803
-
Rocha NP, de Miranda AS, Teixeira AL. Insights into Neuroinflammation in Parkinson's Disease: From Biomarkers to Anti-Inflammatory Based Therapies. BioMed Res Int. 2015;2015:628192. Pubmed Central PMCID: 4532803.
-
(2015)
BioMed Res Int
, vol.2015
, pp. 628192
-
-
Rocha, N.P.1
De Miranda, A.S.2
Teixeira, A.L.3
-
50
-
-
38949195712
-
L-DOPA-induced dyskinesia: Cellular mechanisms and approaches to treatment
-
18267248
-
Cenci MA. L-DOPA-induced dyskinesia: cellular mechanisms and approaches to treatment. Parkinsonism Relat Disord. 2007;13 Suppl 3:S263-7.
-
(2007)
Parkinsonism Relat Disord
, vol.13
, Issue.3
, pp. S263-S267
-
-
Cenci, M.A.1
-
51
-
-
0036024973
-
In vivo and in organello assessment of OXPHOS activities
-
1:CAS:528:DC%2BD38Xks1Ghurg%3D 12054921
-
Barrientos A. In vivo and in organello assessment of OXPHOS activities. Methods. 2002;26(4):307-16.
-
(2002)
Methods
, vol.26
, Issue.4
, pp. 307-316
-
-
Barrientos, A.1
-
52
-
-
67649506191
-
Tests to assess motor phenotype in mice: A user's guide
-
1:CAS:528:DC%2BD1MXntVWisr4%3D 19513088
-
Brooks SP, Dunnett SB. Tests to assess motor phenotype in mice: a user's guide. Nat Rev Neurosci. 2009;10(7):519-29.
-
(2009)
Nat Rev Neurosci
, vol.10
, Issue.7
, pp. 519-529
-
-
Brooks, S.P.1
Dunnett, S.B.2
|