The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

Virology

Volumn 493, Issue , 2016, Pages 217-226

  Frumence, Etienne ^a   Roche, Marjolaine ^a   Krejbich Trotot, Pascale ^a   El Kalamouni, Chaker ^a   Nativel, Brice ^a   Rondeau, Philippe ^a   Missé, Dorothée ^b   Gadea, Gilles ^a   Viranaicken, Wildriss ^a   Desprès, Philippe ^a  

^a UNIVERSITÉ DE LA RÉUNION   (France)

^b CNRS   (France)

Author keywords

Apoptosis; Arbovirus; Emerging virus; Human epithelial cells; Innate immunity; Oxidative stress; Type I interferon; Viral pathogenicity; Zika virus

Indexed keywords

BETA INTERFERON; CASPASE 3; CASPASE 7; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; CYTOKINE;

A549 CELL LINE; APOPTOSIS; ARTICLE; CELL COUNT; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; EPIDEMIOLOGICAL DATA; FLAVIVIRUS INFECTION; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IFIT GENE; IL1B GENE; IL6 GENE; IL8 GENE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIROGENESIS; VIRUS REPLICATION; VIRUS STRAIN; ZIKA VIRUS INFECTION; A-549 CELL LINE; ANIMAL; AUTOPHAGY; BIOSYNTHESIS; CHLOROCEBUS AETHIOPS; GENETICS; LUNG ALVEOLUS EPITHELIUM CELL; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); VERO CELL LINE; VIROLOGY; ZIKA VIRUS;

A549 CELLS; ALVEOLAR EPITHELIAL CELLS; ANIMALS; APOPTOSIS; AUTOPHAGY; CERCOPITHECUS AETHIOPS; CYTOKINES; HUMANS; INTERFERON-BETA; MITOCHONDRIA; VERO CELLS; VIRUS REPLICATION; ZIKA VIRUS;

EID: 84962436399     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2016.03.006     Document Type: Article

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