Cascade regulation of PPARγ2 and C/EBPα signaling pathways by celastrol impairs adipocyte differentiation and stimulates lipolysis in 3T3-L1 adipocytes

Metabolism: Clinical and Experimental

Volumn 65, Issue 5, 2016, Pages 646-654

  Choi, Seung Kug ^a   Park, Sunmi ^a   Jang, Subin ^a   Cho, Hun Hee ^a   Lee, Siwoo ^b   You, Seungkwon ^a   Kim, Sang Hyuk ^b   Moon, Hyun Seuk ^a,c  

^a Korea University   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

Adipocytes differentiation; C EBP ; Celastrol; Lipolysis; PPAR 2

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CELASTROL; FATTY ACID; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCEROL; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRIACYLGLYCEROL; ANTINEOPLASTIC AGENT; ANTIOBESITY AGENT; ANTIOXIDANT; BIOLOGICAL MARKER; INSECTICIDE; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIPTERINE; TRITERPENE;

3T3 CELL LINE; ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; LIPID STORAGE; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOXICITY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ADIPOGENESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLISM; MOUSE; WHITE ADIPOCYTE;

3T3-L1 CELLS; ADIPOCYTES, WHITE; ADIPOGENESIS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-OBESITY AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; BIOMARKERS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL SURVIVAL; GENE EXPRESSION REGULATION; INSECTICIDES; KINETICS; LIPOLYSIS; MICE; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 84962376483     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2016.01.009     Document Type: Article

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