Some GCR polymorphisms (N363S, ER22/23EK, and Bcl-1) may influence steroid-induced toxicities and survival rates in children with ALL

Journal of Pediatric Hematology/Oncology

Volumn 38, Issue 5, 2016, Pages 334-340

  Eipel, Oliver ^a   Hegyi, Márta ^a   Csordás, Katalin ^b   Németh, Krisztina ^a   Luczay, Andrea ^a   Török, Dóra ^a   Csóka, Monika ^a   Erdélyi, Dániel ^a   Kovács, Gábor ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b United St István and St Lá szló Hospital   (Hungary)

Author keywords

Acute lymphoid leukemia; Bcl 1; ER22 23EK; Glucocorticoid receptor gene; Individualized therapy; N363S; Single nucleotide polymorphism; Steroid related toxicities

Indexed keywords

AMINO ACID; BCL 1 PROTEIN; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; ONCOPROTEIN; PREDNISONE; UNCLASSIFIED DRUG; CYCLIN D1; STEROID;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; BEHAVIOR DISORDER; CANCER PROGNOSIS; CANCER SURVIVAL; CHILD; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISORDERS OF CARBOHYDRATE METABOLISM; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; DRUG RESPONSE; DRUG SAFETY; DRUG SENSITIVITY; DRUG TOLERABILITY; EVENT FREE SURVIVAL; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENOTYPE; GLUCOCORTICOID RECEPTOR GENE; HUMAN; HYPERTENSION; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NEUROTOXICITY; ONCOGENE; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL RATE; SURVIVAL TIME; COMPLICATION; DISEASE FREE SURVIVAL; GENETIC POLYMORPHISM; GENETICS; INFANT; MORTALITY; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CYCLIN D1; DISEASE-FREE SURVIVAL; GLUCOCORTICOIDS; HUMANS; INFANT; POLYMORPHISM, GENETIC; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREDNISONE; PROGNOSIS; RECEPTORS, GLUCOCORTICOID; STEROIDS; SURVIVAL RATE;

EID: 84962360834     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0000000000000535     Document Type: Article

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