Preclinical effects of honokiol on treating glioblastoma multiforme via G1 phase arrest and cell apoptosis

Phytomedicine

Volumn 23, Issue 5, 2016, Pages 517-527

  Lin, Chien Ju ^a   Chang, Ya An ^a   Lin, Yi Ling ^b   Liu, Shing Hwa ^c   Chang, Cheng Kuei ^d   Chen, Ruei Ming ^a,b,e  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Cell cycle arrest; Honokiol; Malignant glioma; p53 CD1 CDKs E2F1

Indexed keywords

BETA ACTIN; CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; HONOKIOL; PIFITHRIN ALPHA; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; BENZOTHIAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; CASPASE; CELL CYCLE PROTEIN; LIGNAN; PIFITHRIN; TOLUENE; TP53 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL LINE; CELL CYCLE ARREST; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IC50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; DRUG EFFECTS; METABOLISM; NUDE MOUSE; PRECLINICAL STUDY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BENZOTHIAZOLES; BIPHENYL COMPOUNDS; CASPASES; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; FEMALE; G1 PHASE; GLIOBLASTOMA; HUMANS; LIGNANS; MICE; MICE, INBRED BALB C; MICE, NUDE; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84962224173     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2016.02.021     Document Type: Article

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