Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 7, 2012, Pages 879-887

  Ishikawa, Chie ^a   Arbiser, Jack L ^b,c   Mori, Naoki ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

Adult T cell leukemia; Cell survival; Honokiol; Human T cell leukemia virus type 1; Signaling

Indexed keywords

CASPASE; CASPASE 3; CASPASE 9; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; HONOKIOL; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 2; MYC PROTEIN; PROTEIN CIAP 2; PROTEIN KINASE B; STAT PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; SURVIVIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T CELL LEUKEMIA;

ADULT; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; HUMANS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; LIGNANS; MICE; MICE, INBRED ICR; MICE, SCID; NF-KAPPA B; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

HUMAN T-LYMPHOTROPIC VIRUS 1; MUS;

EID: 84860858957     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.03.009     Document Type: Article

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