Immunoproteomic profiling of antiviral antibodies in new-onset type 1 diabetes using protein arrays

Diabetes

Volumn 65, Issue 1, 2016, Pages 285-296

  Bian, Xiaofang ^a   Wallstrom, Garrick ^a   Davis, Amy ^a   Wang, Jie ^a   Park, Jin ^a   Throop, Andrea ^a   Steel, Jason ^a   Yu, Xiaobo ^a   Wasserfall, Clive ^b   Schatz, Desmond ^b   Atkinson, Mark ^b   Qiu, Ji ^a   LaBaer, Joshua ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEOME; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN; AUTOANTIBODY; CATION TRANSPORT PROTEIN; GLUTAMATE DECARBOXYLASE; ICA512 AUTOANTIBODY; SLC30A8 PROTEIN, HUMAN; VIRAL PROTEIN;

ADOLESCENT; ADULT; ANTIBODY RESPONSE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; FEMALE; HUMAN; HUMORAL IMMUNITY; IMMUNOPROTEOMICS; INFECTION RATE; INSULIN DEPENDENT DIABETES MELLITUS; MALE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN MICROARRAY; PROTEOMICS; VIRUS INFECTION; VIRUS STRAIN; CASE CONTROL STUDY; COXSACKIE VIRUS INFECTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; ENDOGENOUS RETROVIRUS; ENTEROVIRUS B; HIGH THROUGHPUT SCREENING; IMMUNOLOGY; MUMPS; MUMPS VIRUS; PRESCHOOL CHILD; ROTAVIRUS; ROTAVIRUS INFECTION; RUBELLA; RUBELLA VIRUS; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIBODIES, VIRAL; AUTOANTIBODIES; CASE-CONTROL STUDIES; CATION TRANSPORT PROTEINS; CHILD; CHILD, PRESCHOOL; COXSACKIEVIRUS INFECTIONS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DIABETES MELLITUS, TYPE 1; ENDOGENOUS RETROVIRUSES; ENTEROVIRUS B, HUMAN; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; GLUTAMATE DECARBOXYLASE; HERPESVIRUS 4, HUMAN; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MALE; MUMPS; MUMPS VIRUS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; ROTAVIRUS; ROTAVIRUS INFECTIONS; RUBELLA; RUBELLA VIRUS; VIRAL PROTEINS; YOUNG ADULT;

EID: 84962182170     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0179     Document Type: Article

References (58)

1. Onkamo P, Väänänen S, Karvonen M, Tuomilehto J. Worldwide increase in incidence of Type I diabetes-the analysis of the data on published incidence trends. Diabetologia 1999;42:1395-1403
2. Redondo MJ, Jeffrey J, Fain PR, Eisenbarth GS, Orban T. Concordance for islet autoimmunity among monozygotic twins. N Engl J Med 2008;359:2849-2850
3. Eringsmark Regnéll S, Lernmark A. The environment and the origins of islet autoimmunity and type 1 diabetes. Diabet Med 2013;30:155-160
4. Craig ME, Nair S, Stein H, Rawlinson WD. Viruses and type 1 diabetes: a new look at an old story. Pediatr Diabetes 2013;14:149-158
5. Roivainen M, Klingel K. Virus infections and type 1 diabetes risk. Curr Diab Rep 2010;10:350-356
6. Schneider DA, von Herrath MG. Potential viral pathogenic mechanism in human type 1 diabetes. Diabetologia 2014;57:2009-2018
7. Parikka V, Näntö-Salonen K, Saarinen M, et al. Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk. Diabetologia 2012;55:1926-1936
8. Chmiel R, Giannopoulou EZ, Winkler C, Achenbach P, Ziegler AG, Bonifacio E. Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: implications for early screening. Diabetologia 2015;58:411-413
9. Stene LC, Oikarinen S, Hyöty H, et al. Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes 2010;59:3174-3180
10. Gamble DR, Kinsley ML, FitzGerald MG, Bolton R, Taylor KW. Viral antibodies in diabetes mellitus. BMJ 1969;3:627-630
11. Banatvala JE, Bryant J, Schernthaner G, et al. Coxsackie B, mumps, rubella, and cytomegalovirus specific IgM responses in patients with juvenile-onset insulin-dependent diabetes mellitus in Britain, Austria, and Australia. Lancet 1985;1:1409-1412
12. Foy CA, Quirke P, Lewis FA, Futers TS, Bodansky HJ. Detection of common viruses using the polymerase chain reaction to assess levels of viral presence in type 1 (insulin-dependent) diabetic patients. Diabet Med 1995;12:1002-1008
13. Pak CY, Eun HM, McArthur RG, Yoon JW. Association of cytomegalovirus infection with autoimmune type 1 diabetes. Lancet 1988;2:1-4
14. Ylipaasto P, Klingel K, Lindberg AM, et al. Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia 2004;47:225-239
15. Dotta F, Censini S, van Halteren AG, et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A 2007;104:5115-5120
16. Oikarinen S, Tauriainen S, Hober D, et al.; VirDiab Study Group. Virus antibody survey in different European populations indicates risk association between coxsackievirus B1 and type 1 diabetes. Diabetes 2014;63:655-662
17. Laitinen OHHH, Honkanen H, Pakkanen O, et al. Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes. Diabetes 2014;63:446-455
18. Lee HS, Briese T, Winkler C, et al.; TEDDY study group. Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes. Diabetologia 2013;56:1705-1711
19. Yoon JW, Austin M, Onodera T, Notkins AL. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 1979;300:1173-1179
20. Conrad B, Weissmahr RN, Böni J, Arcari R, Schüpbach J, Mach B. A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell 1997;90:303-313
21. Honeyman MC, Coulson BS, Stone NL, et al. Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. Diabetes 2000;49:1319-1324
22. Forrest JM, Menser MA, Harley JD. Diabetes mellitus and congenital rubella. Pediatrics 1969;44:445-447
23. Festa F, Steel J, Bian X, Labaer J. High-throughput cloning and expression library creation for functional proteomics. Proteomics 2013;13:1381-1399
24. Seiler CY, Park JG, Sharma A, et al. DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research. Nucleic Acids Res 2014;42:D1253-D1260
25. Miersch S, LaBaer J. Nucleic acid programmable protein arrays: versatile tools for array-based functional protein studies. Curr Protoc Protein Sci 2011; Chapter 27:Unit27.2
26. Miersch S, Bian X, Wallstrom G, et al. Serological autoantibody profiling of type 1 diabetes by protein arrays. J Proteomics 2013;94:486-496
27. Takulapalli BR, Qiu J, Magee DM, et al. High density diffusion-free nanowell arrays. J Proteome Res 2012;11:4382-4391
28. Yu X, Woolery AR, Luong P, et al. Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays. Mol Cell Proteomics 2014;13:3164-3176
29. Ramachandran N, Raphael JV, Hainsworth E, et al. Next-generation high-density self-assembling functional protein arrays. Nat Methods 2008;5:535-538
30. Qiu J, LaBaer J. Nucleic acid programmable protein array a just-in-time multiplexed protein expression and purification platform. Methods Enzymol 2011; 500:151-163
31. Breslow NE, Day NE. Statistical methods in cancer research. Volume I - The analysis of case-control studies. IARC Sci Publ 1980;5-338
32. Tramper-Stranders GA, van der Ent CK, Slieker MG, et al. Diagnostic value of serological tests against Pseudomonas aeruginosa in a large cystic fibrosis population. Thorax 2006;61:689-693
33. Mejía-León ME, Petrosino JF, Ajami NJ, Domínguez-Bello MG, de la Barca AM. Fecal microbiota imbalance in Mexican children with type 1 diabetes. Sci Rep 2014;4:3814
34. Vogetseder W, Dumfahrt A, Mayersbach P, Schönitzer D, Dierich MP. Antibodies in human sera recognizing a recombinant outer membrane protein encoded by the envelope gene of the human endogenous retrovirus K. AIDS Res Hum Retroviruses 1993;9:687-694
35. Eisenhut M, Schwarz TF, Hegenscheid B. Seroprevalence of dengue, chi-kungunya and Sindbis virus infections in German aid workers. Infection 1999;27: 82-85
36. Nwanegbo E, Vardas E, Gao W, et al. Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States. Clin Diagn Lab Immunol 2004; 11:351-357
37. Staras SA, Dollard SC, Radford KW, Flanders WD, Pass RF, Cannon MJ. Seroprevalence of cytomegalovirus infection in the United States, 1988-1994. Clin Infect Dis 2006;43:1143-1151
38. Dunne EF, Unger ER, Sternberg M, et al. Prevalence of HPV infection among females in the United States. JAMA 2007;297:813-819
39. Weinbaum CM, Williams I, Mast EE, et al.; Centers for Disease Control and Prevention (CDC). Recommendations for identification and public health management of persons with chronic hepatitis B virus infection. MMWR Recomm Rep 2008;57:1-20
40. Butel JS. Patterns of polyomavirus SV40 infections and associated cancers in humans: a model. Curr Opin Virol 2012;2:508-514
41. Balfour HH Jr, Sifakis F, Sliman JA, Knight JA, Schmeling DO, Thomas W. Age-specific prevalence of Epstein-Barr virus infection among individuals aged 6-19 years in the United States and factors affecting its acquisition. J Infect Dis 2013;208:1286-1293
42. Cherry JD, Harriman KH. Why do vaccine-preventable disease outbreaks occur in the United States? [article online], 2012. Available from http://www.idse .net/download/VPD-IDSE12-WM.pdf. Accessed October 2012
43. Latner DR, McGrew M, Williams NJ, Sowers SB, Bellini WJ, Hickman CJ. Estimates of mumps seroprevalence may be influenced by antibody specificity and serologic method. Clin Vaccine Immunol 2014;21:286-297
44. Burgess JA, Kirkpatrick KL, Menser MA. Fulminant onset of diabetes mellitus during an attack of infectious mononucleosis. Med J Aust 1974;2:706-707
45. Foy CA, Quirke P, Williams DJ, et al. A search for candidate viruses in type 1 diabetic pancreas using the polymerase chain reaction. Diabet Med 1994;11: 564-569
46. Elliott RBPC, Pilcher CC. Epstein-Barr virus infection is not associated with islet cell and insulin auto-antibody seroconversion. Diabetologia 1995; 38:1130
47. Hyöty H, Räsänen L, Hiltunen M, Lehtinen M, Huupponen T, Leinikki P. Decreased antibody reactivity to Epstein-Barr virus capsid antigen in type 1 (insulin-dependent) diabetes mellitus. APMIS 1991;99:359-363
48. Hornef MW, Wagner HJ, Kruse A, Kirchner H. Cytokine production in a whole-blood assay after Epstein-Barr virus infection in vivo. Clin Diagn Lab Immunol 1995;2:209-213
49. Williams H, McAulay K, Macsween KF, et al. The immune response to primary EBV infection: a role for natural killer cells. Br J Haematol 2005;129: 266-274
50. Parkkonen P, Hyöty H, Ilonen J, Reijonen H, Ylä-Herttuala S, Leinikki P; Childhood Diabetes in Finland Study Group. Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 beta chain. Clin Exp Immunol 1994;95:287-293
51. Richardson SJ, Horwitz MS. Is type 1 diabetes "going viral"? Diabetes 2014;63:2203-2205
52. Buschard K, Madsbad S. A longitudinal study of virus antibodies in patients with newly diagnosed type 1 (insulin-dependent) diabetes mellitus. J Clin Lab Immunol 1984;13:65-70
53. Schernthaner G, Banatvala JE, Scherbaum W, et al. Coxsackie-B-virus-specific IgM responses, complement-fixing islet-cell antibodies, HLA DR antigens, and C-peptide secretion in insulin-dependent diabetes mellitus. Lancet 1985;2: 630-632
54. Field LL, McArthur RG, Shin SY, Yoon JW. The relationship between Coxsackie-B-virus-specific IgG responses and genetic factors (HLA-DR, GM, KM) in insulin-dependent diabetes mellitus. Diabetes Res 1987;6: 169-173
55. Çekin Y, Özkaya E, Gülkesen H, Akçurin S, Çolak D. Investigation of en-terovirus infections, autoimmune factors and HLA genotypes in patients with T1DM. Minerva Endocrinol 2014;39:67-74
56. Anderson KS, Ramachandran N, Wong J, et al. Application of protein mi-croarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. J Proteome Res 2008;7:1490-1499
57. Anderson KS, Sibani S, Wallstrom G, et al. Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer. J Proteome Res 2011;10:85-96
58. Salvatoni A, Baj A, Bianchi G, Federico G, Colombo M, Toniolo A. Intra-familial spread of enterovirus infections at the clinical onset of type 1 diabetes. Pediatr Diabetes 2013;14:407-416