Intrafamilial spread of enterovirus infections at the clinical onset of type 1 diabetes

Pediatric Diabetes

Volumn 14, Issue 6, 2013, Pages 407-416

  Salvatoni, Alessandro ^a   Baj, Andreina ^a   Bianchi, Giuliana ^a   Federico, Giovanni ^b   Colombo, Martina ^a   Toniolo, Antonio ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

Adolescent; Autoantibodies; Biomarker; Child; Enterovirus; Family; Parent; Pathogenesis; PCR; Sibling; Type 1 diabetes; Virology; Virus

Indexed keywords

RNA;

ADOLESCENT; ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD DONOR; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE TRANSMISSION; ENTEROVIRUS; ENTEROVIRUS INFECTION; FAMILY; FEMALE; FOLLOW UP; GENOME; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE; MALE; OBESITY; ONSET AGE; PARENT; PLASMA; PRESCHOOL CHILD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SCHOOL CHILD; SHORT STATURE; SIBLING; SPECIES IDENTIFICATION; VIRUS DETECTION;

ADOLESCENT; AUTOANTIBODIES; BIOMARKER; CHILD; ENTEROVIRUS; FAMILY; PARENT; PATHOGENESIS; PCR; SIBLING; TYPE 1 DIABETES; VIROLOGY; VIRUS;

ADOLESCENT; AUTOIMMUNE DISEASES; CHILD; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; ENTEROVIRUS A, HUMAN; ENTEROVIRUS B, HUMAN; ENTEROVIRUS C, HUMAN; ENTEROVIRUS D, HUMAN; ENTEROVIRUS INFECTIONS; FAMILY HEALTH; FEMALE; FOLLOW-UP STUDIES; HUMANS; ITALY; MALE; MOLECULAR TYPING; PARENTS; PREVALENCE; SIBLINGS;

EID: 84882647740     PISSN: 1399543X     EISSN: 13995448     Source Type: Journal    
DOI: 10.1111/pedi.12056     Document Type: Article

References (46)

1. Lernmark A, Larsson HE. Immune therapy in type 1 diabetes mellitus. Nat Rev Endocrinol 2013: 9: 92-103.
2. Atkinson MA. The pathogenesis and natural history of type 1 diabetes. Cold Spring Harb Perspect Med 2012: 2: a007641.
3. Knip M, Simell O. Environmental triggers of type 1 diabetes. Cold Spring Harb Perspect Med 2012: 2: a007690. doi:10.1101/cshperspect.a007690.
4. Chiu SW-Y, Leslie DR, Beyan H. Non-genetic factors in the pathogenesis of type 1 diabetes. In: Hyoty H, Taylor K, Toniolo A, Zuckerman A, eds. Diabetes and Viruses. New York: Springer Science, 2012: 25-34.
5. Skog O, Korsgren S, Melhus A, Korsgren O. Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease. Curr Opin Endocrinol Diabetes Obes 2013: 20: 118-123.
6. Skyler JS. Primary and secondary prevention of Type 1 diabetes. Diabet Med 2013: 30: 161-169.
7. de Goffau MC, Luopajärvi K, Knip M et al. Fecal microbiota composition differs between children with β-cell autoimmunity and those without. Diabetes 2013: 62: 1238-1244.
8. von Herrath M, Filippi C, Coppieters K. How viral infections enhance or prevent type 1 diabetes-from mouse to man. J Med Virol 2011: 83: 1672.
9. Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 2011: 342: d35.
10. Richardson SJ, Leete P, Bone AJ, Foulis AK, Morgan NG. Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1. Diabetologia 2013: 56: 185-193.
11. Hyoty H, Taylor KW. Viruses as major environmental factors in the induction of diabetes. In: Hyoty H, Taylor K, Toniolo A, Zuckerman A, eds. Diabetes and Viruses. New York: Springer Science, 2012: 349-355.
12. Diaz-Horta O, Baj A, Maccari G, Salvatoni A, Toniolo A. Enteroviruses and causality of type 1 diabetes: how close are we? Pediatr Diabetes 2012: 13: 92-99.
13. Hober D, Sauter P. Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host. Nat Rev Endocrinol 2010: 6: 279-289.
14. Frisk G, Friman G, Tuvemo T, Fohlman J, Diderholm H. Coxsackie B virus IgM in children at onset of type 1 (insulin-dependent) diabetes mellitus: evidence for IgM induction by a recent or current infection. Diabetologia 1992: 35: 249-253.
15. Oikarinen S, Martiskainen M, Tauriainen S et al. Enterovirus RNA in blood is linked to the development of type 1 diabetes. Diabetes 2011: 60: 276-279.
16. Stene LC, Oikarinen S, Hyöty H et al. Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes 2010: 59: 3174-3180.
17. Tapia G, Cinek O, Rasmussen T et al. Human enterovirus RNA in monthly fecal samples and islet autoimmunity in Norwegian children with high genetic risk for type 1 diabetes: the MIDIA study. Diabetes Care 2011: 34: 151-155.
18. Oberste MS. Comparative genomics of the coxsackie B viruses and related enteroviruses. Curr Top Microbiol Immunol 2008: 323: 33-47.
19. Sane F, Alidjinou EK, Kacet N et al. Human milk can neutralize Coxsackievirus B4 in vitro. J Med Virol 2013: 85: 880-887.
20. Tracy S, Drescher KM, Jackson JD, Kim K, Kono K. Enteroviruses, type 1 diabetes and hygiene: a complex relationship. Rev Med Virol 2010: 20: 106-116.
21. Salur L, Oikarinen S, Tauriainen S, Mandel M, Hyöty H, Uibo R. Enterovirus infections in young infants: are children still protected by maternal antibodies? Hum Vaccin 2011: 7: 966-971.
22. Kogon A, Spigland I, Frothingham TE et al. The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. VII. Observations on viral excretion, seroimmunity, intrafamilial spread and illness association in coxsackie and echovirus infections. Am J Epidemiol 1969: 89: 51-61.
23. Taylor KW. Epidemiology of viruses in type 1 diabetes: seasonal incidence, family studies, clustering. In: Hyoty H, Taylor K, Toniolo A, Zuckerman A, eds. Diabetes and Viruses. New York: Springer Science, 2012: 25-34.
24. Nishmi M, Yodfat Y. Successive overlapping outbreaks of a febrile illness associated with coxsackie virus type B4 and ECHO virus type 9 in a kibbutz. Isr J Med Sci 1973: 9: 895-899.
25. Wenner HA, Abel D, Olson LC, Burry VF. A mixed epidemic associated with echovirus types 6 and 11: virologic, clinical and epidemiologic studies. Am J Epidemiol 1981: 114: 369-378.
26. Lagercrantz M, Hugo H, Sterner G. Spread of echovirus type 18 infections within families. Scand J Infect Dis 1973: 5: 249-252.
27. Hamaguchi T, Fujisawa H, Sakai K et al. Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult. Emerg Infect Dis 2008: 14: 828-830.
28. Chen Z, Chumakov K, Dragunsky E et al. Chimpanzee-human monoclonal antibodies for treatment of chronic poliovirus excretors and emergency postexposure prophylaxis. J Virol 2011: 85: 4354-4362.
29. DeVries AS, Harper J, Murray A et al. Vaccine-derived poliomyelitis 12 years after infection in Minnesota. N Engl J Med 2011: 364: 2316-2323.
30. Cheng LL, Ng PC, Chan PK, Wong HL, Cheng FW, Tang JW. Probable intrafamilial transmission of coxsackievirus B3 with vertical transmission, severe early-onset neonatal hepatitis, and prolonged viral RNA shedding. Pediatrics 2006: 118: 929-933.
31. Lévêque N, Renois F, Talmud D et al. Quantitative genomic and antigenomic enterovirus RNA detection in explanted heart tissue samples from patients with end-stage idiopathic dilated cardiomyopathy. J Clin Microbiol 2012: 50: 3378-3380.
32. Chapman NM, Kim KS. Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy. Curr Top Microbiol Immunol 2008: 323: 275-292.
33. Bonifacio E, Genovese S, Braghi S et al. Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity. Diabetologia 1995: 38: 816-822.
34. Bonifacio E, Lampasona V, Genovese S, Ferrari M, Bosi E. Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies. J Immunol 1995: 155: 5419-5426.
35. Lampasona V, Petrone A, Tiberti C et al. Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes. Diabetes Care 2010: 33: 104-108.
36. Naserke HE, Dozio N, Ziegler AG, Bonifacio E. Comparison of a novel micro-assay for insulin autoantibodies with the conventional radiobinding assay. Diabetologia 1998: 41: 681-683.
37. Cabrera-Rode E, Díaz-Horta Oscar, Toniolo A, Sarmiento L. Type 1 diabetes in the tropics: a link with enterovirus infections. In: Hyoty H, Taylor K, Toniolo A, Zuckerman A, eds. Diabetes and Viruses. New York: Springer Science, 2012: 195-206.
38. Odoom JK, Yunus Z, Dunn G, Minor PD, Martín J. Changes in population dynamics during long-term evolution of sabin type 1 poliovirus in an immunodeficient patient. J Virol 2008: 82: 9179-9190.
39. Cavalcante P, Barberis M, Cannone M et al. Detection of poliovirus-infected macrophages in thymus of patients with myasthenia gravis. Neurology 2010: 74: 1118-1126.
40. Karavidas A, Lazaros G, Noutsias M et al. Recurrent coxsackie B viral myocarditis leading to progressive impairment of left ventricular function over 8 years. Int J Cardiol 2011: 151: e65-e67.
41. Oikarinen M, Tauriainen S, Oikarinen S et al. Type 1 diabetes is associated with enterovirus infection in gut mucosa. Diabetes 2012: 61: 687-691.
42. Mercalli A, Lampasona V, Klingel K et al. No evidence of enteroviruses in the intestine of patients with type 1 diabetes. Diabetologia 2012: 55: 2479-2488.
43. Smura T, Kakkola L, Blomqvist S et al. Molecular evolution and epidemiology of echovirus 6 in Finland. Infect Genet Evol 2013: 16C: 234-247.
44. Oberste MS, Feeroz MM, Maher K et al. Characterizing the picornavirus landscape among synanthropic nonhuman primates in Bangladesh, 2007 to 2008. J Virol 2013: 87: 558-571.
45. Shoshan A, Sella T, Shohat T, Goren I, Shalev V, Chodick G. A case-crossover study of infectious diseases and new diagnosis of type 1 diabetes. Pediatr Diabetes 2012: 13: 583-586.
46. Toniolo A, Salvatoni A, Federico G, Diaz-Horta O, Maccari G, Baj A. Enteroviruses in blood. In: Hyoty H, Taylor K, Toniolo A, Zuckerman A, eds. Diabetes and Viruses. New York: Springer, 2012: 143-156.