Virus antibody survey in different european populations indicates risk association between coxsackievirus B1 and type 1 diabetes

Diabetes

Volumn 63, Issue 2, 2014, Pages 655-662

  Oikarinen, Sami ^a   Tauriainen, Sisko ^a,b   Hober, Didier ^c   Lucas, Bernadette ^c   Vazeou, Andriani ^d   Sioofy Khojine, Amirbabak ^a   Bozas, Evangelos ^d   Muir, Peter ^e,n   Honkanen, Hanna ^a   Ilonen, Jorma ^b,f   Knip, Mikael ^a,g,h,i   Keskinen, Päivi ^a   Saha, Marja Terttu ^a   Huhtala, Heini ^a   Stanway, Glyn ^j   Bartsocas, Christos ^d   Ludvigsson, Johnny ^k   Taylor, Keith ^l   Hyöty, Heikki ^a,m  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c University Lille   (France)

^d UNIVERSITY OF ATHENS   (Greece)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

^g FOLKHÄLSAN RESEARCH CENTER   (Finland)

^h UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

ⁱ UNIVERSITY OF HELSINKI   (Finland)

^j UNIVERSITY OF ESSEX   (United Kingdom)

^k LINKÖPING UNIVERSITY   (Sweden)

^l QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^m PIRKANMAA HOSPITAL DISTRICT   (Finland)

ⁿ PUBLIC HEALTH ENGLAND   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ADULT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CHILD; CONTROLLED STUDY; COXSACKIE VIRUS B; COXSACKIE VIRUS B1; COXSACKIE VIRUS B3; COXSACKIE VIRUS B4; DIABETIC PATIENT; DISEASE ASSOCIATION; EUROPE; FEMALE; GENOTYPE; HEALTH SURVEY; HLA SYSTEM; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEROTYPE; YOUNG ADULT;

ADOLESCENT; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COXSACKIEVIRUS INFECTIONS; DIABETES MELLITUS, TYPE 1; ENTEROVIRUS B, HUMAN; EUROPE; FEMALE; GENOTYPE; HLA-DQ ANTIGENS; HUMANS; INFANT; MALE; RISK FACTORS; YOUNG ADULT;

EID: 84893045342     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0620     Document Type: Article

References (34)

1. Coppieters KT, Boettler T, von Herrath M. Virus infections in type 1 diabetes. Cold Spring Harb Perspect Med 2012;2:a007682
2. Tam PE, Schmidt AM, Ytterberg SR, Messner RP. Duration of virus persistence and its relationship to inflammation in the chronic phase of coxsackievirus B1-induced murine polymyositis. J Lab Clin Med 1994;123: 346-356
3. Williams V, Brichler S, Radjef N, et al. Hepatitis delta virus proteins repress hepatitis B virus enhancers and activate the alpha/beta interferon-inducible MxA gene. J Gen Virol 2009;90:2759-2767
4. Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ 2011;342:d35
5. Green J, Casabonne D, Newton R. Coxsackie B virus serology and type 1 diabetes mellitus: a systematic review of published case-control studies. Diabet Med 2004;21:507-514
6. Oikarinen M, Tauriainen S, Honkanen T, et al. Analysis of pancreas tissue in a child positive for islet cell antibodies. Diabetologia 2008;51:1796-1802
7. Martino TA, Petric M, Weingartl H, et al. The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus. Virology 2000;271:99-108
8. Richardson SJ, Leete P, Bone AJ, Foulis AK, Morgan NG. Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1. Diabetologia 2013;56:185-193
9. Richardson SJ, Willcox A, Bone AJ, Foulis AK, Morgan NG. The prevalence of enteroviral capsid protein VP1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia 2009;52:1143-1151
10. Ylipaasto P, Klingel K, Lindberg AM, et al. Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia 2004;47:225-239
11. Gamble DR, Kinsley ML, FitzGerald MG, Bolton R, Taylor KW. Viral antibodies in diabetes mellitus. BMJ 1969;3:627-630
12. Yoon JW, Austin M, Onodera T, Notkins AL. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 1979;300: 1173-1179
13. Dotta F, Censini S, van Halteren AG, et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A 2007;104:5115-5120
14. Laitinen OH, Honkanen H, Pakkanen O, et al. Coxsackievirus B1 is associated with induction of b-cell autoimmunity that portends type 1 diabetes. Diabetes 2014;63:446-455
15. Näntö-Salonen K, Kupila A, Simell S, et al. Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial. Lancet 2008;372:1746-1755
16. Nix WA, Oberste MS, Pallansch MA. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol 2006;44:2698-2704
17. Viskari H, Ludvigsson J, Uibo R, et al. Relationship between the incidence of type 1 diabetes and maternal enterovirus antibodies: time trends and geographical variation. Diabetologia 2005;48:1280-1287
18. Kukko M, Kimpimäki T, Korhonen S, et al. Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population. J Clin Endocrinol Metab 2005;90:2712-2717
19. Hermann R, Turpeinen H, Laine AP, et al. HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families. Tissue Antigens 2003;62:162-169
20. Sadeharju K, Knip M, Hiltunen M, Akerblom HK, Hyöty H. The HLA-DR phenotype modulates the humoral immune response to enterovirus antigens. Diabetologia 2003;46:1100-1105
21. Oikarinen S, Martiskainen M, Tauriainen S, et al. Enterovirus RNA in blood is linked to the development of type 1 diabetes. Diabetes 2011;60:276-279
22. Lanteri MC, Kaidarova Z, Peterson T, et al. Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study. PLoS ONE 2011;6:e22948
23. Ma Y, Yuan B, Yi J, et al. The genetic polymorphisms of HLA are strongly correlated with the disease severity after Hantaan virus infection in the Chinese Han population. Clin Dev Immunol 2012;2012:308237
24. Saliba GS, Franklin SL, Jackson GG. ECHO-11 as a respiratory virus: quantitation of infection in man. J Clin Invest 1968;47:1303-1313
25. Westerhuis BM, Koen G, Wildenbeest JG, et al. Specific cell tropism and neutralization of human parechovirus types 1 and 3: implications for pathogenesis and therapy development. J Gen Virol 2012;93:2363-2370
26. Viskari H, Ludvigsson J, Uibo R, et al. Relationship between the incidence of type 1 diabetes and enterovirus infections in different European populations: results from the EPIVIR project. J Med Virol 2004;72:610-617
27. Knip M. Pathogenesis of type 1 diabetes: implications for incidence trends. Horm Res Paediatr 2011;76(Suppl. 1):57-64
28. Viskari HR, Koskela P, Lönnrot M, et al. Can enterovirus infections explain the increasing incidence of type 1 diabetes? Diabetes Care 2000;23:414-416
29. Larsson PG, Lakshmikanth T, Svedin E, King C, Flodström-Tullberg M. Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice. Diabetologia 2013;56:867-874
30. Nurminen N, Oikarinen S, Hyöty H. Virus infections as potential targets of preventive treatments for type 1 diabetes. Rev Diabet Stud 2012;9:260-271
31. Wikswo ME, Khetsuriani N, Fowlkes AL, et al. Increased activity of Coxsackievirus B1 strains associated with severe disease among young infants in the United States, 2007-2008. Clin Infect Dis 2009;49:e44-e51
32. Jenson AB, Rosenberg HS, Notkins AL. Pancreatic islet-cell damage in children with fatal viral infections. Lancet 1980;2:354-358
33. Lansdown AB. Pathological changes in the pancreas of mice following infection with Coxsackie B viruses. Br J Exp Pathol 1976;57:331-338
34. Toniolo A, Onodera T, Jordan G, Yoon JW, Notkins AL. Virus-induced diabetes mellitus. Glucose abnormalities produced in mice by the six members of the Coxsackie B virus group. Diabetes 1982;31:496-499