Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells

Phytomedicine

Volumn 23, Issue 5, 2016, Pages 566-577

  Baek, Seung Ho ^a   Ko, Jeong Hyeon ^a   Lee, Hanwool ^a   Jung, Jinhong ^b   Kong, Moonkyoo ^b   Lee, Jung Woo ^b   Lee, Junhee ^a   Chinnathambi, Arunachalam ^c   Zayed, Me ^c   Alharbi, Sulaiman Ali ^c   Lee, Seok Geun ^a   Shim, Bum Sang ^a   Sethi, Gautam ^c,d   Kim, Sung Hoon ^a   Yang, Woong Mo ^a   Um, Jae Young ^a   Ahn, Kwang Seok ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Resveratrol; SOCS 1; Squamous cell carcinoma of the head and neck; STAT3

Indexed keywords

JANUS KINASE 2; MESSENGER RNA; PERVANADATE; PHOSPHATASE; PROTEIN KINASE; RESVERATROL; SERINE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TYROSINE; JAK1 PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; JANUS KINASE 1; PROTEIN TYROSINE KINASE; RADIOSENSITIZING AGENT; SOCS1 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; STILBENE DERIVATIVE; SUPPRESSOR OF CYTOKINE SIGNALING;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HEAD AND NECK TUMOR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOSENSITIZATION; SIGNAL TRANSDUCTION; TUMOR CELL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RADIATION RESPONSE; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; HEAD AND NECK NEOPLASMS; HUMANS; JANUS KINASE 1; JANUS KINASE 2; PHOSPHORYLATION; RADIATION-SENSITIZING AGENTS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; STILBENES; SUPPRESSOR OF CYTOKINE SIGNALING 1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84962168822     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2016.02.011     Document Type: Article

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