Amyotrophic lateral sclerosis and environmental factors

Functional Neurology

Volumn 31, Issue 1, 2016, Pages 7-19

  Bozzoni, Virginia ^a,b   Pansarasa, Orietta ^b   Diamanti, Luca ^a,b   Nosari, Guido ^a,b   Cereda, Cristina ^b   Ceroni, Mauro ^a,b  

^a UNIVERSITY OF PAVIA   (Italy)

^b C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

Author keywords

ALS; BMAA; Electromagnetic fields; Metals; Pesticides; Sports

Indexed keywords

2 AMINO 3 METHYLAMINOPROPIONIC ACID; BETHANECHOL; CADMIUM; CARBAMATE PESTICIDE; IRON; HEAVY METAL; PESTICIDE;

AMYOTROPHIC LATERAL SCLEROSIS; BLOOD BRAIN BARRIER; DEGENERATIVE DISEASE; ELECTRIC SHOCK; ELECTROMAGNETIC FIELD; ENVIRONMENTAL FACTOR; FOOTBALL; FRONTOTEMPORAL DEMENTIA; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HEAD INJURY; HEAVY METAL BLOOD LEVEL; HUMAN; META ANALYSIS (TOPIC); MOTONEURON; NERVE DEGENERATION; NONHUMAN; PHYSICAL ACTIVITY; PREVALENCE; REVIEW; SYSTEMATIC REVIEW (TOPIC); ADVERSE EFFECTS; ELECTROMAGNETISM; ENVIRONMENTAL EXPOSURE; RISK FACTOR; SPORT;

AMYOTROPHIC LATERAL SCLEROSIS; ELECTROMAGNETIC FIELDS; ENVIRONMENTAL EXPOSURE; HUMANS; METALS, HEAVY; PESTICIDES; RISK FACTORS; SPORTS;

EID: 84962129160     PISSN: 03935264     EISSN: 19713274     Source Type: Journal    
DOI: 10.11138/FNeur/2016.31.1.007     Document Type: Review

References (62)

1. Abel EL (2007). Football increases the risk for Lou Gehrig’s disease, amyotrophic lateral sclerosis. Percept Mot Skills 104: 1251-1254.
2. Armon C (2007). Sports and trauma in amyotrophic lateral sclerosis revisited. J Neurol Sci 262:45-53.
3. Atassi N, Ratai EM, Greenblatt DJ, et al (2010). A phase I, pharmacokinetic, dosage escalation study of creatine monohydrate in subjects with amyotrophic lateral sclerosis. Amyotroph Lateral Scler 11:508-513.
4. Banack SA, Caller TA, Stommel EW (2010). The cyanobacteria derived toxin beta-N-methylamino-L-alanine and amyotrophic lateral sclerosis. Toxins (Basel) 2:2837-2850.
5. Bäumer D, Talbot K, Turner (2014). Advances in motor neurone disease. J R Soc Medicine 107:14-21.
6. Belli S, Vanacore N (2005). Proportionate mortality of Italian soccer players: is amyotrophic lateral sclerosis an occupational disease? Eur J Epidemiol 20:237-242.
7. Bellingham MC (2011). A review of the neural mechanisms of action and clinical efficiency of riluzole in in treating amyotrophic lateral sclerosis: what have we learned in the last decade? CNS Neurosci Ther 17:4-31.
8. Bonvicini F, Marcello N, Mandrioli J, et al. (2010). Exposure to pesticides and risk of amyotrophic lateral sclerosis: a population-based case-control study. Ann Ist Super Sanita 46:284-287.
9. Burns CJ, Beard KK, Cartmill JB (2001). Mortality in chemical workers potentially exposed to 2,4-dichlorophenoxyacetic acid (2,4-D) 1945-94: an update. Occup Environ Med 58:24-30.
10. Capozzella A, Sacco C, Chighine A, et al (2014). Work related etiology of amyotrophic lateral sclerosis (ALS): a metaanalysis. Ann Ig 26:456-472.
11. Cereda C, Gabanti E, Corato M, et al (2006). Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 7:227-234
12. Chen H, Richard M, Sandler DP, et al (2007). Head injury and amyotrophic lateral sclerosis. Am J Epidemiol 166:810-816.
13. Chiò A, Logroscino G, Traynor BJ, et al (2013). Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature. Neuroepidemiology 41:118-130.
14. Chio A, Calvo A, Dossena M, et al (2009). ALS in Italian professional soccer players: the risk is still present and could be soccer-specific. Amyotroph Lateral Scler 10:205-209.
15. Chiò A, Benzi G, Dossena M, et al (2005). Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players. Brain 128:472-476.
16. Chiu AS, Gehringer MM, Welch JH, et al (2011). Does α-amino -β-methylaminopropionic acid (BMAA) play a role in neurodegeneration? Int J Environ Res Public Health 8:3728-3746.
17. Cox PA, Banack SA, Murch SJ (2003). Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam. Proc Natl Acad Sci U S A 100: 13380-13383.
18. Diamanti L, Gagliardi S, Cereda C, et al. (2013). Genetics of ALS and correlations between genotype and phenotype in ALS — A focus on Italian population. http://www.intecho-pen.com/books/current-advances-in-amyotrophic-lateral-sclerosis/genetics-of-als-and-correlations-between-geno-type-and-phenotype-in-als-a-focus-on-italian-population
19. Duncan MW, Steele JC, Kopin IJ, et al (1990). 2-amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam. Neurology 40:767-772.
20. Dunlop RA, Cox PA, Banack SA, et al (2013). The non-protein amino acid BMAA is misincorporated into human proteins in place of L-serine causing protein misfolding and aggregation. PLoS One 8:e75376.
21. Fang F, Kwee LC, Allen KD, et al (2010). Association between blood lead and the risk of amyotrophic lateral sclerosis. Am J Epidemiol 171:1126-1133.
22. Gagliardi S, Abel K, Bianchi M, et al (2013). Regulation of FMO and PON detoxication systems in ALS human tissues. Neurotox Res 23:370-377.
23. Gagliardi S, Ogliari P, Davin A, et al (2011). Flavin-containing monooxygenase mRNA levels are up-regulated in als brain areas in SOD1-mutant mice. Neurotox Res 20:150-158.
24. Håkansson N, Gustavsson P, Johansen C, et al (2003). Neurodegenerative diseases in welders and other workers exposed to high levels of magnetic fields. Epidemiology 14:420-426.
25. Hamidou B, Couratier P, Besançon C, et al (2014). Epidemiological evidence that physical activity is not a risk factor for ALS. Eur J Epidemiol 29:459-475.
26. Huisman MH, Seelen M, de Jong SW, et al (2013). Lifetime physical activity and the risk of amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 84:976-981.
27. Huss A, Spoerri A, Egger M, et al (2014). Occupational exposure to magnetic fields and electric shocks and risk of ALS: The Swiss National Cohort. Amyotroph Lateral Scler Frontotemporal Degener 16:80-85.
28. Julien JP (2001). Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded. Cell 104:581-591.
29. Kamel F, Umbach DM, Lehman TA, et al (2003). Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. Environ Health Perspect 111:1335-1339.
30. Kamel F, Umbach DM, Bedlack RS, et al (2012). Pesticide exposure and amyotrophic lateral sclerosis. Neurotoxicology 33:457-462.
31. Klivenyi P, Ferrante RJ, Matthews RT, et al (1999). Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med 5:347-350.
32. Lehman EJ, Hein MJ, Baron SL, et al (2012). Neurodegenerative causes of death among retired National Football League players. Neurology 79:1970-1974.
33. Malek AM, Barchowsky A, Bowser R, et al (2014). Environmental and occupational risk factors for amyotrophic lateral sclerosis: a case-control study. Neurodegen Dis 14:31-38.
34. Malek AM, Barchowsky A, Bowser R, et al (2012). Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies. Environ Res 117:112-119.
35. Masseret E, Banack S, Boumédiène F, et al (2013). Dietary BMAA exposure in an amyotrophic lateral sclerosis cluster from southern France. PLoS One 8:e83406.
36. McGuire V, Longstreth WT Jr, Nelson LM, et al (1997). Occupational exposures and amyotrophic lateral sclerosis. A population-based case-control study. Am J Epidemiol 145:1076-1088.
37. Morahan JM, Yu B, Trent RJ, et al (2007). Genetic susceptibility to environmental toxicants in ALS. Am J Med Genet B Neuropsychiatr Genet 144B: 885-890.
38. Morahan JM, Pamphlett R (2006). Amyotrophic lateral sclerosis and exposure to environmental toxins: an Australian case-control study. Neuroepidemiology 27: 130-135.
39. Pablo J, Banack SA, Cox PA, et al (2009). Cyanobacterial neurotoxin BMAA in ALS and Alzheimer’s disease. Acta Neurol Scand 120:216-225.
40. Pamphlett R (2012). Exposure to environmental toxins and the risk of sporadic motor neuron disease: an expanded Australian case-control study. Eur J Neurol 19:1343-1348.
41. Pellecchia MT, Pivonello R, Monsurrò MR, et al (2010). The GH-IGF system in amyotrophic lateral sclerosis: correlations between pituitary GH secretion capacity, insulin-like growth factors and clinical features. Eur J Neurol 17:666-671.
42. Piscopo P, Crestini A, Adduci A, et al (2011). Altered oxidative stress profile in the cortex of mice fed an enriched branched-chain amino acids diet: possible link with amyotrophic lateral sclerosis? J Neurosci Res 89:1276-1283.
43. Pupillo E, Messina P, Giussani G, et al (2014). Physical activity and amyotrophic lateral sclerosis: a European population- based case-control study. Ann Neurol 75:708-716.
44. Qureshi MM, Hayden D, Urbinelli L, et al (2006). Analysis of factors that modify susceptibility and rate of progression in amyotrophic lateral sclerosis (ALS). Amyotroph Lateral Scler 7: 173-182.
45. Rosenfeld J, King RM, Jackson CE, et al (2008). Creatine mono- hydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS. Amyotroph Lateral Scler 9:266-272.
46. Saccà F, Quarantelli M, Rinaldi C, et al (2012). A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: Clinical, neuroimaging, and hormonal results. J Neurol 259:132-138.
47. Savica R, Parisi JE, Wold LE, et al (2012). High school football and risk of neurodegeneration: a community-based study. Mayo Clin Proc 87:335-340.
48. Seelen M, Vermeulen RC, van Dillen LS, et al (2014). Residential exposure to extremely low frequency electromagnetic fields and the risk of ALS. Neurology 83:1767-1769.
49. Slowik A, Tomik B, Wolkow PP, et al (2006). Paraoxonase gene polymorphisms and sporadic ALS. Neurology 67: 766-770.
50. Steyn FJ, Ngo ST, Lee JD, et al (2012). Impairments to the GH- IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology 153:3735-3746.
51. Sutedja NA, Veldink JH, Fischer K, et al (2009). Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: a systematic review. Amyotroph Lateral Scler 10:302-309.
52. Testa D, Caraceni T, Fetoni V (1989). Branched-chain amino acids in the treatment of amyotrophic lateral sclerosis. J Neurol 236:445-447.
53. Ticozzi N, LeClerc AL, Keagle PJ, et al (2010). Paraoxonase gene mutations in amyotrophic lateral sclerosis. Ann Neurol 68:102-107.
54. Trojsi F, Monsurrò MR, Tedeschi G (2013). Exposure to environmental toxicants and pathogenesis of amyotrophic lateral sclerosis: State of the art and research perspectives. Int J Mol Sci 14:15286-15311.
55. Valenti M, Pontieri FE, Conti F, et al (2005). Amyotrophic lateral sclerosis and sports: a case-control study. Eur J Neurol 12:223-225.
56. Vanacore N, Binazzi A, Bottazzi M, et al (2006). Amyotrophic lateral sclerosis in an Italian professional soccer player. Parkinsonism Relat Disord 12:327-329.
57. Veldink JH, Kalmijn S, Groeneveld GJ, et al (2005). Physical activity and the association with sporadic ALS. Neurology 64:241-245.
58. Venerosi A, Martire A, Rungi A, et al (2011). Complex behavioral and synaptic effects of dietary branched chain amino acids in a mouse model of amyotrophic lateral sclerosis. Mol Nutr Food Res 55:541-552.
59. Vergara X, Mezei G, Kheifets L (2015). Case-control study of occupational exposure to electric shocks and magnetic fields and mortality from amyotrophic lateral sclerosis in the US, 1991-1999. J Expo Sci Environ Epidemiol 25:65-71.
60. Weisskopf MG, Morozova N, O’Reilly EJ, et al (2009). Prospective study of chemical exposures and amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 80:558-561.
61. Wicks P, Ganesalingham J, Collin C, et al (2007). Three soccer playing friends with simultaneous amyotrophic lateral sclerosis. Amyotroph Lateral Scler 8:177-179.
62. Zhou H, Chen G, Chen C, et al (2012). Association between extremely low-frequency electromagnetic fields occupations and amyotrophic lateral sclerosis: a meta-analysis. PLoS One 7:e48354.