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Volumn 23, Issue 4, 2013, Pages 370-377

Regulation of FMO and PON detoxication systems in ALS human tissues

Author keywords

ALS; Exposure to toxins; FMO; PON; qPCR

Indexed keywords

ARYLDIALKYLPHOSPHATASE; DIMETHYLANILINE MONOOXYGENASE; MESSENGER RNA; TOXIN; XENOBIOTIC AGENT;

EID: 84876288474     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-012-9356-1     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 34547949775 scopus 로고    scopus 로고
    • Football increases the risk for Lou Gehrig's disease, amyotrophic lateral sclerosis
    • 17879657
    • Abel El (2007) Football increases the risk for Lou Gehrig's disease, amyotrophic lateral sclerosis. Percept Mot Skills 104(3 Pt 2):1251-1254
    • (2007) Percept Mot Skills , vol.104 , Issue.3 PART 2 , pp. 1251-1254
    • Abel, E.1
  • 2
    • 79960826526 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: What role does environment play?
    • 21803219 10.1016/j.ncl.2011.06.001
    • Ahmed A, Wicklund MP (2011) Amyotrophic lateral sclerosis: what role does environment play? Neurol Clin 29(3):689-711
    • (2011) Neurol Clin , vol.29 , Issue.3 , pp. 689-711
    • Ahmed, A.1    Wicklund, M.P.2
  • 3
    • 0034574407 scopus 로고    scopus 로고
    • World federation of neurology research group on motor neuron diseases. El Escorial revisited: Revisited criteria for the diagnosis of amyotrophic lateral sclerosis
    • 10.1080/146608200300079536 1:STN:280:DC%2BD3Mvhs1Ghsg%3D%3D
    • Brooks BR, Miller RG, Swash M, Munsat TL (2000) World federation of neurology research group on motor neuron diseases. El Escorial revisited: revisited criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Later Scler 1:293-299
    • (2000) Amyotroph Later Scler , vol.1 , pp. 293-299
    • Brooks, B.R.1    Miller, R.G.2    Swash, M.3    Munsat, T.L.4
  • 4
    • 79959773203 scopus 로고    scopus 로고
    • Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures
    • 21431535 10.1007/978-1-60761-999-4-30 1:CAS:528:DC%2BC3MXls1Ols78%3D
    • Camarillo C, Swerdel M, Hart R (2011) Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures. Methods Mol Biol 698(Part 4):419-429
    • (2011) Methods Mol Biol , vol.698 , Issue.PART 4 , pp. 419-429
    • Camarillo, C.1    Swerdel, M.2    Hart, R.3
  • 5
    • 0028945438 scopus 로고
    • Structural and catalytic properties of the mammalian flavin-containing monooxygenase
    • 7766799 10.1021/tx00044a001 1:STN:280:DyaK2M3osValsg%3D%3D
    • Cashman JR (1995) Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem Res Toxicol 8(2):166-181
    • (1995) Chem Res Toxicol , vol.8 , Issue.2 , pp. 166-181
    • Cashman, J.R.1
  • 6
    • 33144459248 scopus 로고    scopus 로고
    • Human flavin-containing monooxygenases
    • 16402899 10.1146/annurev.pharmtox.46.120604.141043 1:CAS:528: DC%2BD28XisFKltLs%3D
    • Cashman JR, Zhang J (2006) Human flavin-containing monooxygenases. Annu Rev Pharmacol Toxicol 46:65-100
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 65-100
    • Cashman, J.R.1    Zhang, J.2
  • 7
    • 33847176637 scopus 로고    scopus 로고
    • Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis
    • 17127561 10.1080/17482960600864413 1:CAS:528:DC%2BD2sXmsVSjtw%3D%3D
    • Cereda C, Gabanti E, Corato M, de Silvestri A, Alimonti D, Cova E, Malaspina A, Ceroni M (2006) Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 7(4):227-234
    • (2006) Amyotroph Lateral Scler , vol.7 , Issue.4 , pp. 227-234
    • Cereda, C.1    Gabanti, E.2    Corato, M.3    De Silvestri, A.4    Alimonti, D.5    Cova, E.6    Malaspina, A.7    Ceroni, M.8
  • 8
    • 0037312798 scopus 로고    scopus 로고
    • Association between occupational exposure to power frequency electromagnetic fields and amyotrophic lateral sclerosis: A review
    • 12541277 10.1002/ajim.10148
    • Li CY, Sung FC (2003) Association between occupational exposure to power frequency electromagnetic fields and amyotrophic lateral sclerosis: a review. Am J Ind Med 43(2):212-220
    • (2003) Am J Ind Med , vol.43 , Issue.2 , pp. 212-220
    • Li, C.Y.1    Sung, F.C.2
  • 9
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • 11715057 10.1038/35097565 1:CAS:528:DC%2BD38Xmt1WitLs%3D
    • Cleveland DW, Rothstein JD (2001) From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2:806
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 11
    • 0037704264 scopus 로고    scopus 로고
    • Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity
    • 12519632 10.1080/13547500210148315 1:CAS:528:DC%2BD3sXitVOksg%3D%3D
    • Costa LG, Richter RJ, Li WF, Cole T, Guizzetti M, Furlong CE (2003) Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers 8(1):1-12
    • (2003) Biomarkers , vol.8 , Issue.1 , pp. 1-12
    • Costa, L.G.1    Richter, R.J.2    Li, W.F.3    Cole, T.4    Guizzetti, M.5    Furlong, C.E.6
  • 13
    • 80052623000 scopus 로고    scopus 로고
    • Flavin-containing monooxygenase (FMO) mRNA levels are up-regulated in ALS brain areas in SOD1-mutant mice
    • 21082301 10.1007/s12640-010-9230-y 1:CAS:528:DC%2BC3MXpt1ylsbw%3D
    • Gagliardi S, Ogliari P, Davin A, Corato M, Cova E, Abel K, Cashman JR, Ceroni M, Cereda C (2011) Flavin-containing monooxygenase (FMO) mRNA levels are up-regulated in ALS brain areas in SOD1-mutant mice. Neurotox Res 20:150-158
    • (2011) Neurotox Res , vol.20 , pp. 150-158
    • Gagliardi, S.1    Ogliari, P.2    Davin, A.3    Corato, M.4    Cova, E.5    Abel, K.6    Cashman, J.R.7    Ceroni, M.8    Cereda, C.9
  • 14
    • 49849094080 scopus 로고    scopus 로고
    • Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS
    • 18030339 10.1371/journal.pone.0001205
    • Garbuzova-Davis S, Saporta S, Haller E, Kolomey I, Bennett SP, Potter H, Sanberg PR (2007) Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS. PLoS ONE 2(11):e1205
    • (2007) PLoS ONE , vol.2 , Issue.11 , pp. 1205
    • Garbuzova-Davis, S.1    Saporta, S.2    Haller, E.3    Kolomey, I.4    Bennett, S.P.5    Potter, H.6    Sanberg, P.R.7
  • 15
    • 0025189320 scopus 로고
    • Purification and characterization of xenobiotic-metabolizing enzymes from lung tissue
    • 2405438 10.1016/0163-7258(90)90068-D 1:CAS:528:DyaK3cXltV2lsQ%3D%3D
    • Guengerich FP (1990) Purification and characterization of xenobiotic-metabolizing enzymes from lung tissue. Pharmacol Ther 45(3):299-307
    • (1990) Pharmacol Ther , vol.45 , Issue.3 , pp. 299-307
    • Guengerich, F.P.1
  • 16
    • 34247213490 scopus 로고    scopus 로고
    • Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation
    • 17404154 10.1161/CIRCULATIONAHA.106.681700 1:CAS:528:DC%2BD2sXjvFKjur8%3D
    • Horke S, Witte I, Wilgenbus P, Kruger M, Strand D, Forstermann U (2007) Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation. Circulation 115:2055-2064
    • (2007) Circulation , vol.115 , pp. 2055-2064
    • Horke, S.1    Witte, I.2    Wilgenbus, P.3    Kruger, M.4    Strand, D.5    Forstermann, U.6
  • 17
    • 70349749966 scopus 로고    scopus 로고
    • The role of environmental mercury, lead and pesticide exposure in development of amyotrophic lateral sclerosis
    • 19632272 10.1016/j.neuro.2009.07.010 1:CAS:528:DC%2BD1MXht1CqtL7K [Epub 2009 Jul 24]
    • Johnson FO, Atchison WD (2009) The role of environmental mercury, lead and pesticide exposure in development of amyotrophic lateral sclerosis. Neurotoxicology 30(5):761-765 [Epub 2009 Jul 24]
    • (2009) Neurotoxicology , vol.30 , Issue.5 , pp. 761-765
    • Johnson, F.O.1    Atchison, W.D.2
  • 18
    • 0032538072 scopus 로고    scopus 로고
    • Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver
    • 9813235 10.1016/S0304-4165(98)00069-5 1:CAS:528:DyaK1cXmslGqu7Y%3D
    • Kawaji A, Isobe M, Tochino Y, Takabatake E, Chikaoka Y, Nomura Y, Tamura M (1998) Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver. Biochim Biophys Acta 1425(1):41-46
    • (1998) Biochim Biophys Acta , vol.1425 , Issue.1 , pp. 41-46
    • Kawaji, A.1    Isobe, M.2    Tochino, Y.3    Takabatake, E.4    Chikaoka, Y.5    Nomura, Y.6    Tamura, M.7
  • 19
    • 0026720427 scopus 로고
    • Content of the neurotoxins cycasin (methylazoxymethanol beta-d-glucoside) and BMAA (beta-N-methylamino-l-alanine) in cycad flour prepared by Guam Chamorros
    • 1620343 10.1212/WNL.42.7.1336 1:CAS:528:DyaK38Xls12kt70%3D
    • Kisby GE, Ellison M, Spencer PS (1992) Content of the neurotoxins cycasin (methylazoxymethanol beta-d-glucoside) and BMAA (beta-N-methylamino-l-alanine) in cycad flour prepared by Guam Chamorros. Neurology 42(7):1336-1340
    • (1992) Neurology , vol.42 , Issue.7 , pp. 1336-1340
    • Kisby, G.E.1    Ellison, M.2    Spencer, P.S.3
  • 20
    • 0025859281 scopus 로고
    • Oxygen radicals: Common mediators of neurotoxicity
    • 10.1016/0892-0362(91)90081-7
    • LeBel CP, Bondy SC (1990) Oxygen radicals: common mediators of neurotoxicity. Neurotoxicol Teratol 13:341-346
    • (1990) Neurotoxicol Teratol , vol.13 , pp. 341-346
    • Lebel, C.P.1    Bondy, S.C.2
  • 21
    • 0025313038 scopus 로고
    • Organometal-induced increases in oxygen reactive species: The potential of 2′,7′-dichlorofluorescin diacetate as an index of neurotoxic damage
    • 10.1016/0041-008X(90)90278-3
    • LeBel CP, Ali S, McKee M, Bondy SC (1990) Organometal-induced increases in oxygen reactive species: the potential of 2′,7′- dichlorofluorescin diacetate as an index of neurotoxic damage. Toxicol Appl Pharmacol 104:341-346
    • (1990) Toxicol Appl Pharmacol , vol.104 , pp. 341-346
    • Lebel, C.P.1    Ali, S.2    McKee, M.3    Bondy, S.C.4
  • 22
    • 81855182096 scopus 로고    scopus 로고
    • Guam dementia syndrome revisited in 2011
    • 21986681 10.1097/WCO.0b013e32834cd50a
    • Lee SE (2011) Guam dementia syndrome revisited in 2011. Curr Opin Neurol 24(6):517-524
    • (2011) Curr Opin Neurol , vol.24 , Issue.6 , pp. 517-524
    • Lee, S.E.1
  • 23
    • 37149022666 scopus 로고    scopus 로고
    • Biological role, protein expression, subcellular localization and oxidative stress response of paraoxonase2 in the intestine of humans and rats
    • 17916643 10.1152/ajpgi.00369.2007 1:CAS:528:DC%2BD2sXhsVGls7fL
    • Levy E, Trudel K, Bendayan M, Seidman EG, Delvin E, Lavoie JC, Precourt LP, Amre D, Sinnett D (2007) Biological role, protein expression, subcellular localization and oxidative stress response of paraoxonase2 in the intestine of humans and rats. Am J Physiol Gastrointest Liver Physiol 293:G1252-G1261
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293
    • Levy, E.1    Trudel, K.2    Bendayan, M.3    Seidman, E.G.4    Delvin, E.5    Lavoie, J.C.6    Precourt, L.P.7    Amre, D.8    Sinnett, D.9
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • 11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D
    • Livak, Schmittgen (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25(4):402-408
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak1    Schmittgen2
  • 25
    • 33744950956 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle
    • 10.1002/mus.20542 1:CAS:528:DC%2BD28XmtlKntbc%3D
    • Mahoney DJ, Kaczor JJ, Bourgeois J, Yasuda N, Tarnopolsky MA (2006) Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle. Muscle Nerv Jun 33(6):809-816
    • (2006) Muscle Nerv Jun , vol.33 , Issue.6 , pp. 809-816
    • Mahoney, D.J.1    Kaczor, J.J.2    Bourgeois, J.3    Yasuda, N.4    Tarnopolsky, M.A.5
  • 26
    • 0035085455 scopus 로고    scopus 로고
    • Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
    • 11279269 10.1046/j.1471-4159.2001.t01-1-00231.x 1:CAS:528: DC%2BD3MXis1Klt7c%3D
    • Malaspina A, Kaushik N, de Belleroche J (2001) Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J Neurochem 77(1):132-145
    • (2001) J Neurochem , vol.77 , Issue.1 , pp. 132-145
    • Malaspina, A.1    Kaushik, N.2    De Belleroche, J.3
  • 27
    • 0001557462 scopus 로고
    • Neurologic diseases on the island of Guam
    • 1:STN:280:DyaG2M%2FivVyjsg%3D%3D
    • Mulder DW, Kurland LT, Iriarte LL (1954) Neurologic diseases on the island of Guam. US Armed Forces Med J 5(12):1724-1739
    • (1954) US Armed Forces Med J , vol.5 , Issue.12 , pp. 1724-1739
    • Mulder, D.W.1    Kurland, L.T.2    Iriarte, L.L.3
  • 28
    • 0035976903 scopus 로고    scopus 로고
    • Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein
    • 11579088 10.1074/jbc.M105660200 1:CAS:528:DC%2BD3MXovFegsLg%3D
    • Ng CJ, Wadleigh DJ, Gangopadhyay A, Hama S, Grijalva VR, Navab M, Fogelman AM, Reddy ST (2001) Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein. J Biol Chem 276(48):44444-44449
    • (2001) J Biol Chem , vol.276 , Issue.48 , pp. 44444-44449
    • Ng, C.J.1    Wadleigh, D.J.2    Gangopadhyay, A.3    Hama, S.4    Grijalva, V.R.5    Navab, M.6    Fogelman, A.M.7    Reddy, S.T.8
  • 29
    • 0029910477 scopus 로고    scopus 로고
    • Uptake of inorganic mercury by the human brain
    • 8922066 10.1007/s004010050556 1:STN:280:DyaK2s%2FotVOgsw%3D%3D
    • Pamphlett R, Waley P (1996) Uptake of inorganic mercury by the human brain. Acta Neuropathol 92(5):525-527
    • (1996) Acta Neuropathol , vol.92 , Issue.5 , pp. 525-527
    • Pamphlett, R.1    Waley, P.2
  • 30
    • 80855143654 scopus 로고    scopus 로고
    • Association between environmental exposure to pesticides and neurodegenerative diseases
    • 10.1016/j.taap.2011.05.006
    • Parrón T, Mar R, Hernández AF, Alarcón R (2011) Association between environmental exposure to pesticides and neurodegenerative diseases. Toxicol Appl Pharmacolog 256(3):379-385
    • (2011) Toxicol Appl Pharmacolog , vol.256 , Issue.3 , pp. 379-385
    • Parrón, T.1    Mar, R.2    Hernández, A.F.3    Alarcón, R.4
  • 33
    • 0347753257 scopus 로고    scopus 로고
    • Decreased macrophage paraoxonase 2 expression in patients with hypercholesterolemia is the result of their increased cellular cholesterol content: Effect of atorvastatin therapy
    • 14592851 10.1161/01.ATV.0000104011.88939.06 1:CAS:528:DC%2BD3sXhtVWhurjL
    • Rosenblat M, Hayek T, Hussein K, Aviram M (2004) Decreased macrophage paraoxonase 2 expression in patients with hypercholesterolemia is the result of their increased cellular cholesterol content: effect of atorvastatin therapy. Arterioscler Thromb Vasc Biol 24:175-180
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 175-180
    • Rosenblat, M.1    Hayek, T.2    Hussein, K.3    Aviram, M.4
  • 34
    • 23144448320 scopus 로고    scopus 로고
    • Molecular and cellular pathways of neurodegeneration in motor neurone disease
    • 16024877 10.1136/jnnp.2004.048652 1:STN:280:DC%2BD2Mzms1yntA%3D%3D
    • Shaw PJ (2005) Molecular and cellular pathways of neurodegeneration in motor neurone disease. J Neurol Neurosurg Psychiatry 76:1046-1057
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1046-1057
    • Shaw, P.J.1
  • 35
    • 33748583199 scopus 로고    scopus 로고
    • A biphasic U-shape effect of cellular oxidative stress on the macrophage anti-oxidant paraoxonase 2 (PON2) enzymatic activity
    • 16970920 10.1016/j.bbrc.2006.08.150 1:CAS:528:DC%2BD28XpvFCqtbk%3D
    • Shiner M, Fuhrman B, Aviram M (2006) A biphasic U-shape effect of cellular oxidative stress on the macrophage anti-oxidant paraoxonase 2 (PON2) enzymatic activity. Biochem Biophys Res Commun 349:1094-1099
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1094-1099
    • Shiner, M.1    Fuhrman, B.2    Aviram, M.3
  • 37
    • 44949193040 scopus 로고    scopus 로고
    • The ALS/PDC syndrome of Guam and the cycad hypothesis
    • 18490618 10.1212/01.wnl.0000312571.81091.26
    • Steele JC, McGeer PL (2008) The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology 70(21):1984-1990
    • (2008) Neurology , vol.70 , Issue.21 , pp. 1984-1990
    • Steele, J.C.1    McGeer, P.L.2
  • 38
    • 0034602673 scopus 로고    scopus 로고
    • Role of yeast flavin containing monooxygenases is induced by the unfolded protein response
    • 10618381 10.1073/pnas.97.1.121 1:CAS:528:DC%2BD3cXjvVCrsg%3D%3D
    • Suh JK, Robertus JD (2000) Role of yeast flavin containing monooxygenases is induced by the unfolded protein response. Proc Natl Acad Sci USA 97:121-126
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 121-126
    • Suh, J.K.1    Robertus, J.D.2
  • 41
    • 46749107070 scopus 로고    scopus 로고
    • The endoplasmic reticulum-golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS
    • 18337461 10.1096/fj.07-092783 1:CAS:528:DC%2BD1cXotlGntLk%3D [Epub 2008 Mar 12]
    • Urushitani M, Ezzi SA, Matsuo A, Tooyama I, Julien JP (2008) The endoplasmic reticulum-golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS. FASEB J 22(7):2476-2487 [Epub 2008 Mar 12]
    • (2008) FASEB J , vol.22 , Issue.7 , pp. 2476-2487
    • Urushitani, M.1    Ezzi, S.A.2    Matsuo, A.3    Tooyama, I.4    Julien, J.P.5
  • 42
    • 65649135083 scopus 로고    scopus 로고
    • Cigarettes and amyotrophic lateral sclerosis: Only smoke or also fire?
    • 19399854 10.1002/ana.21700
    • Weisskopf MG, Ascherio A (2009) Cigarettes and amyotrophic lateral sclerosis: only smoke or also fire? Ann Neurol 65(4):361-362
    • (2009) Ann Neurol , vol.65 , Issue.4 , pp. 361-362
    • Weisskopf, M.G.1    Ascherio, A.2


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