메뉴 건너뛰기




Volumn 35, Issue 42, 2016, Pages 5480-5488

Epigenetic silencing of miR-124 prevents spermine oxidase regulation: Implications for Helicobacter pylori-induced gastric cancer

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; ENZYME; HYDROGEN PEROXIDE; MESSENGER RNA; MICRORNA 124; SPERMINE OXIDASE; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MICRORNA; MIRN124 MICRORNA, HUMAN; OXIDOREDUCTASE; POLYAMINE OXIDASE;

EID: 84962069872     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.91     Document Type: Article
Times cited : (58)

References (50)
  • 1
    • 0035878846 scopus 로고    scopus 로고
    • Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
    • Wang Y, Devereux W, Woster PM, Stewart TM, Hacker A, Casero RA Jr. Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure. Cancer Res 2001; 61: 5370-5373.
    • (2001) Cancer Res , vol.61 , pp. 5370-5373
    • Wang, Y.1    Devereux, W.2    Woster, P.M.3    Stewart, T.M.4    Hacker, A.5    Casero, R.A.6
  • 2
    • 43549112141 scopus 로고    scopus 로고
    • Nuclear localization of human spermine oxidase isoforms-possible implications in drug response and disease etiology
    • Murray-Stewart T, Wang Y, Goodwin A, Hacker A, Meeker A, Casero RA Jr. Nuclear localization of human spermine oxidase isoforms-possible implications in drug response and disease etiology. FEBS J 2008; 275: 2795-2806.
    • (2008) FEBS J , vol.275 , pp. 2795-2806
    • Murray-Stewart, T.1    Wang, Y.2    Goodwin, A.3    Hacker, A.4    Meeker, A.5    Casero, R.A.6
  • 3
    • 1342280373 scopus 로고    scopus 로고
    • Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoform
    • Cervelli M, Bellini A, Bianchi M, Marcocci L, Nocera S, Polticelli F et al. Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoform. Eur J Biochem 2004; 271: 760-770.
    • (2004) Eur J Biochem , vol.271 , pp. 760-770
    • Cervelli, M.1    Bellini, A.2    Bianchi, M.3    Marcocci, L.4    Nocera, S.5    Polticelli, F.6
  • 5
    • 4544249197 scopus 로고    scopus 로고
    • Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization
    • Chaturvedi R, Cheng Y, Asim M, Bussiere FI, Xu H, Gobert AP et al. Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization. J Biol Chem 2004; 279: 40161-40173.
    • (2004) J Biol Chem , vol.279 , pp. 40161-40173
    • Chaturvedi, R.1    Cheng, Y.2    Asim, M.3    Bussiere, F.I.4    Xu, H.5    Gobert, A.P.6
  • 6
    • 9244225192 scopus 로고    scopus 로고
    • Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: Implications for gastric carcinogenesis
    • Xu H, Chaturvedi R, Cheng Y, Bussiere FI, Asim M, Yao MD et al. Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis. Cancer Res 2004; 64: 8521-8525.
    • (2004) Cancer Res , vol.64 , pp. 8521-8525
    • Xu, H.1    Chaturvedi, R.2    Cheng, Y.3    Bussiere, F.I.4    Asim, M.5    Yao, M.D.6
  • 8
    • 33845730779 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: A potential mechanism for inflammation-induced carcinogenesis
    • Babbar N, Casero RA Jr. Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis. Cancer Res 2006; 66: 11125-11130.
    • (2006) Cancer Res , vol.66 , pp. 11125-11130
    • Babbar, N.1    Casero, R.A.2
  • 9
    • 84901236412 scopus 로고    scopus 로고
    • Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage
    • 1714
    • Chaturvedi R, Asim M, Piazuelo MB, Yan F, Barry DP, Sierra JC et al. Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage. Gastroenterology 2014; 146: 1739-1751, 1714.
    • (2014) Gastroenterology , vol.146 , pp. 1739-1751
    • Chaturvedi, R.1    Asim, M.2    Piazuelo, M.B.3    Yan, F.4    Barry, D.P.5    Sierra, J.C.6
  • 10
    • 43049142306 scopus 로고    scopus 로고
    • Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues
    • Goodwin AC, Jadallah S, Toubaji A, Lecksell K, Hicks JL, Kowalski J et al. Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues. Prostate 2008; 68: 766-772.
    • (2008) Prostate , vol.68 , pp. 766-772
    • Goodwin, A.C.1    Jadallah, S.2    Toubaji, A.3    Lecksell, K.4    Hicks, J.L.5    Kowalski, J.6
  • 11
    • 77956271268 scopus 로고    scopus 로고
    • Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity
    • Hong SK, Chaturvedi R, Piazuelo MB, Coburn LA, Williams CS, Delgado AG et al. Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity. Inflamm Bowel Dis 2010; 16: 1557-1566.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1557-1566
    • Hong, S.K.1    Chaturvedi, R.2    Piazuelo, M.B.3    Coburn, L.A.4    Williams, C.S.5    Delgado, A.G.6
  • 12
    • 80054859726 scopus 로고    scopus 로고
    • Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA
    • 1691 and 1692
    • Chaturvedi R, Asim M, Romero-Gallo J, Barry DP, Hoge S, de Sablet T et al. Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA. Gastroenterology 2011; 141: 1696-1708, 1691 and 1692.
    • (2011) Gastroenterology , vol.141 , pp. 1696-1708
    • Chaturvedi, R.1    Asim, M.2    Romero-Gallo, J.3    Barry, D.P.4    Hoge, S.5    De Sablet, T.6
  • 13
    • 84933041264 scopus 로고    scopus 로고
    • Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase
    • Chaturvedi R, de Sablet T, Asim M, Piazuelo MB, Barry DP, Verriere TG et al. Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase. Oncogene 2015; 34: 3429-3440.
    • (2015) Oncogene , vol.34 , pp. 3429-3440
    • Chaturvedi, R.1    De Sablet, T.2    Asim, M.3    Piazuelo, M.B.4    Barry, D.P.5    Verriere, T.G.6
  • 14
    • 20644440421 scopus 로고    scopus 로고
    • Helicobacter pylori gastritis, peptic ulcer, and gastric cancer: Clinical and molecular aspects
    • Goodwin CS. Helicobacter pylori gastritis, peptic ulcer, and gastric cancer: clinical and molecular aspects. Clin Infect Dis 1997; 25: 1017-1019.
    • (1997) Clin Infect Dis , vol.25 , pp. 1017-1019
    • Goodwin, C.S.1
  • 16
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002; 2: 28-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek, R.M.1    Blaser, M.J.2
  • 17
    • 27744575791 scopus 로고    scopus 로고
    • Helicobacter pylori eradication has the potential to prevent gastric cancer: A stateof-the-art critique
    • Malfertheiner P, Sipponen P, Naumann M, Moayyedi P, Megraud F, Xiao SD et al. Helicobacter pylori eradication has the potential to prevent gastric cancer: a stateof-the-art critique. Am J Gastroenterol 2005; 100: 2100-2115.
    • (2005) Am J Gastroenterol , vol.100 , pp. 2100-2115
    • Malfertheiner, P.1    Sipponen, P.2    Naumann, M.3    Moayyedi, P.4    Megraud, F.5    Xiao, S.D.6
  • 19
    • 2642576923 scopus 로고    scopus 로고
    • Age at acquisition of Helicobacter pylori infection: Comparison of two areas with contrasting risk of gastric cancer
    • Camargo MC, Yepez MC, Ceron C, Guerrero N, Bravo LE, Correa P et al. Age at acquisition of Helicobacter pylori infection: comparison of two areas with contrasting risk of gastric cancer. Helicobacter 2004; 9: 262-270.
    • (2004) Helicobacter , vol.9 , pp. 262-270
    • Camargo, M.C.1    Yepez, M.C.2    Ceron, C.3    Guerrero, N.4    Bravo, L.E.5    Correa, P.6
  • 21
    • 64249160168 scopus 로고    scopus 로고
    • DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect
    • Ando T, Yoshida T, Enomoto S, Asada K, Tatematsu M, Ichinose M et al. DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect. Int J Cancer 2009; 124: 2367-2374.
    • (2009) Int J Cancer , vol.124 , pp. 2367-2374
    • Ando, T.1    Yoshida, T.2    Enomoto, S.3    Asada, K.4    Tatematsu, M.5    Ichinose, M.6
  • 22
    • 84908502237 scopus 로고    scopus 로고
    • DNA methylation of microRNA-124a is a potential risk marker of colitis-associated cancer in patients with ulcerative colitis
    • Ueda Y, Ando T, Nanjo S, Ushijima T, Sugiyama T. DNA methylation of microRNA-124a is a potential risk marker of colitis-associated cancer in patients with ulcerative colitis. Dig Dis Sci 2014; 59: 2444-2451.
    • (2014) Dig Dis Sci , vol.59 , pp. 2444-2451
    • Ueda, Y.1    Ando, T.2    Nanjo, S.3    Ushijima, T.4    Sugiyama, T.5
  • 23
    • 84883489767 scopus 로고    scopus 로고
    • Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells
    • Shi XB, Xue L, Ma AH, Tepper CG, Gandour-Edwards R, Kung HJ et al. Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells. Oncogene 2013; 32: 4130-4138.
    • (2013) Oncogene , vol.32 , pp. 4130-4138
    • Shi, X.B.1    Xue, L.2    Ma, A.H.3    Tepper, C.G.4    Gandour-Edwards, R.5    Kung, H.J.6
  • 24
    • 33847763576 scopus 로고    scopus 로고
    • Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
    • Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setién F et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 2007; 67: 1424-1429.
    • (2007) Cancer Res , vol.67 , pp. 1424-1429
    • Lujambio, A.1    Ropero, S.2    Ballestar, E.3    Fraga, M.F.4    Cerrato, C.5    Setién, F.6
  • 25
    • 84857068434 scopus 로고    scopus 로고
    • Molecular pathways: Involvement of Helicobacter pylori-triggered inflammation in the formation of an epigenetic field defect, and its usefulness as cancer risk and exposure markers
    • Ushijima T, Hattori N. Molecular pathways: involvement of Helicobacter pylori-triggered inflammation in the formation of an epigenetic field defect, and its usefulness as cancer risk and exposure markers. Clin Cancer Res 2012; 18: 923-929.
    • (2012) Clin Cancer Res , vol.18 , pp. 923-929
    • Ushijima, T.1    Hattori, N.2
  • 26
    • 84884373262 scopus 로고    scopus 로고
    • MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis
    • 842
    • Koukos G, Polytarchou C, Kaplan JL, Morley-Fletcher A, Gras-Miralles B, Kokkotou E et al. MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology 2013; 145: 842-852, 842.
    • (2013) Gastroenterology , vol.145 , pp. 842-852
    • Koukos, G.1    Polytarchou, C.2    Kaplan, J.L.3    Morley-Fletcher, A.4    Gras-Miralles, B.5    Kokkotou, E.6
  • 28
    • 34547702823 scopus 로고    scopus 로고
    • Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide
    • Rider JE, Hacker A, Mackintosh CA, Pegg AE, Woster PM, Casero RA Jr. Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide. Amino Acids 2007; 33: 231-240.
    • (2007) Amino Acids , vol.33 , pp. 231-240
    • Rider, J.E.1    Hacker, A.2    MacKintosh, C.A.3    Pegg, A.E.4    Woster, P.M.5    Casero, R.A.6
  • 29
    • 0032433866 scopus 로고    scopus 로고
    • S-adenosylmethionine decarboxylase: Structure, function and regulation by polyamines
    • Pegg AE, Xiong H, Feith DJ, Shantz LM. S-adenosylmethionine decarboxylase: structure, function and regulation by polyamines. Biochem Soc Trans 1998; 26: 580-586.
    • (1998) Biochem Soc Trans , vol.26 , pp. 580-586
    • Pegg, A.E.1    Xiong, H.2    Feith, D.J.3    Shantz, L.M.4
  • 30
    • 84883399007 scopus 로고    scopus 로고
    • Chronic inflammation and oxidative stress: The smoking gun for Helicobacter pylori-induced gastric cancer?
    • Hardbower DM, de Sablet T, Chaturvedi R, Wilson KT. Chronic inflammation and oxidative stress: the smoking gun for Helicobacter pylori-induced gastric cancer? Gut Microbes 2013; 4: 475-481.
    • (2013) Gut Microbes , vol.4 , pp. 475-481
    • Hardbower, D.M.1    De Sablet, T.2    Chaturvedi, R.3    Wilson, K.T.4
  • 31
    • 32944459562 scopus 로고    scopus 로고
    • High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
    • Maekita T, Nakazawa K, Mihara M, Nakajima T, Yanaoka K, Iguchi M et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006; 12: 989-995.
    • (2006) Clin Cancer Res , vol.12 , pp. 989-995
    • Maekita, T.1    Nakazawa, K.2    Mihara, M.3    Nakajima, T.4    Yanaoka, K.5    Iguchi, M.6
  • 32
    • 33845325205 scopus 로고    scopus 로고
    • Higher methylation levels in gastric mucosae significantly correlate with higher risk of gastric cancers
    • Nakajima T, Maekita T, Oda I, Gotoda T, Yamamoto S, Umemura S et al. Higher methylation levels in gastric mucosae significantly correlate with higher risk of gastric cancers. Cancer Epidemiol Biomarkers Prev 2006; 15: 2317-2321.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 2317-2321
    • Nakajima, T.1    Maekita, T.2    Oda, I.3    Gotoda, T.4    Yamamoto, S.5    Umemura, S.6
  • 33
    • 76649145629 scopus 로고    scopus 로고
    • Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells
    • Niwa T, Tsukamoto T, Toyoda T, Mori A, Tanaka H, Maekita T et al. Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res 2010; 70: 1430-1440.
    • (2010) Cancer Res , vol.70 , pp. 1430-1440
    • Niwa, T.1    Tsukamoto, T.2    Toyoda, T.3    Mori, A.4    Tanaka, H.5    Maekita, T.6
  • 34
    • 84887441677 scopus 로고    scopus 로고
    • Virulence of infecting Helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae
    • Schneider BG, Piazuelo MB, Sicinschi LA, Mera R, Peng DF, Roa JC et al. Virulence of infecting Helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae. Epigenetics 2013; 8: 1153-1161.
    • (2013) Epigenetics , vol.8 , pp. 1153-1161
    • Schneider, B.G.1    Piazuelo, M.B.2    Sicinschi, L.A.3    Mera, R.4    Peng, D.F.5    Roa, J.C.6
  • 35
    • 78049518932 scopus 로고    scopus 로고
    • Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer
    • Schneider BG, Peng DF, Camargo MC, Piazuelo MB, Sicinschi LA, Mera R et al. Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer. Int J Cancer 2010; 127: 2588-2597.
    • (2010) Int J Cancer , vol.127 , pp. 2588-2597
    • Schneider, B.G.1    Peng, D.F.2    Camargo, M.C.3    Piazuelo, M.B.4    Sicinschi, L.A.5    Mera, R.6
  • 37
    • 84905174595 scopus 로고    scopus 로고
    • MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer
    • Xie L, Zhang Z, Tan Z, He R, Zeng X, Xie Y et al. MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer. Mol Cell Biochem 2014; 392: 153-159.
    • (2014) Mol Cell Biochem , vol.392 , pp. 153-159
    • Xie, L.1    Zhang, Z.2    Tan, Z.3    He, R.4    Zeng, X.5    Xie, Y.6
  • 38
    • 84905008577 scopus 로고    scopus 로고
    • At the bedside: Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer
    • Dalal RS, Moss SF. At the bedside: Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer. J Leukoc Biol 2014; 96: 213-224.
    • (2014) J Leukoc Biol , vol.96 , pp. 213-224
    • Dalal, R.S.1    Moss, S.F.2
  • 39
    • 84901390048 scopus 로고    scopus 로고
    • Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: Systematic review and meta-analysis of randomised controlled trials
    • Ford AC, Forman D, Hunt RH, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials. BMJ 2014; 348: 3174-3187.
    • (2014) BMJ , vol.348 , pp. 3174-3187
    • Ford, A.C.1    Forman, D.2    Hunt, R.H.3    Yuan, Y.4    Moayyedi, P.5
  • 40
    • 84922365908 scopus 로고    scopus 로고
    • Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study
    • Asada K, Nakajima T, Shimazu T, Yamamichi N, Maekita T, Yokoi C et al. Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study. Gut 2015; 64: 388-396.
    • (2015) Gut , vol.64 , pp. 388-396
    • Asada, K.1    Nakajima, T.2    Shimazu, T.3    Yamamichi, N.4    Maekita, T.5    Yokoi, C.6
  • 41
    • 84863337757 scopus 로고    scopus 로고
    • Transient low doses of DNA demethylating agents exert durable anti-tumor effects on hematological and epithelial tumor cells
    • Tsai H-C, Li H, Van Neste L, Cai Y, Robert C, Rassool FV et al. Transient low doses of DNA demethylating agents exert durable anti-tumor effects on hematological and epithelial tumor cells. Cancer Cell 2012; 21: 430-446.
    • (2012) Cancer Cell , vol.21 , pp. 430-446
    • Tsai, H.-C.1    Li, H.2    Van Neste, L.3    Cai, Y.4    Robert, C.5    Rassool, F.V.6
  • 42
    • 84922181105 scopus 로고    scopus 로고
    • Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
    • Wang H, Jiang Y, Peng H, Chen Y, Zhu P, Huang Y. Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors. Adv Drug Deliv Rev 2015; 81: 142-160.
    • (2015) Adv Drug Deliv Rev , vol.81 , pp. 142-160
    • Wang, H.1    Jiang, Y.2    Peng, H.3    Chen, Y.4    Zhu, P.5    Huang, Y.6
  • 43
    • 81255162523 scopus 로고    scopus 로고
    • Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
    • O'Hagan HM, Wang W, Sen S, Destefano Shields C, Lee SS, Zhang YW et al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer Cell 2011; 20: 606-619.
    • (2011) Cancer Cell , vol.20 , pp. 606-619
    • O'Hagan, H.M.1    Wang, W.2    Sen, S.3    Destefano Shields, C.4    Lee, S.S.5    Zhang, Y.W.6
  • 45
    • 0022490910 scopus 로고
    • Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: Improved separation systems for polyamines in cerebrospinal fluid, urine and tissue
    • Kabra PM, Lee HK, Lubich WP, Marton LJ. Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue. J Chromatogr 1986; 380: 19-32.
    • (1986) J Chromatogr , vol.380 , pp. 19-32
    • Kabra, P.M.1    Lee, H.K.2    Lubich, W.P.3    Marton, L.J.4
  • 46
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 48
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 49
    • 80051547997 scopus 로고    scopus 로고
    • Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk
    • de Sablet T, Piazuelo MB, Shaffer CL, Schneider BG, Asim M, Chaturvedi R et al. Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk. Gut 2011; 60: 1189-1195.
    • (2011) Gut , vol.60 , pp. 1189-1195
    • De Sablet, T.1    Piazuelo, M.B.2    Shaffer, C.L.3    Schneider, B.G.4    Asim, M.5    Chaturvedi, R.6
  • 50
    • 84876478197 scopus 로고    scopus 로고
    • Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer
    • Shimizu T, Suzuki H, Nojima M, Kitamura H, Yamamoto E, Maruyama R et al. Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer. Eur Urol 2013; 63: 1091-1100.
    • (2013) Eur Urol , vol.63 , pp. 1091-1100
    • Shimizu, T.1    Suzuki, H.2    Nojima, M.3    Kitamura, H.4    Yamamoto, E.5    Maruyama, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.