Virulence of infecting helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae

Epigenetics

Volumn 8, Issue 11, 2013, Pages 1153-1161

  Schneider, Barbara G ^a   Blanca Piazuelo, M ^a   Sicinschi, Liviu A ^a,b   Mera, Robertino ^a   Peng, Dun Fa ^a   Roa, Juan Carlos ^c   Romero Gallo, Judith ^a   Delgado, Alberto G ^a   de Sablet, Thibaut ^a   Bravo, Luis E ^d   Wilson, Keith T ^a,e   El Rifai, Wael ^a,e   Peek Jr , Richard M ^a   Correa, Pelayo ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b Holmes Regional Medical Center   (United States)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^d UNIVERSIDAD DEL VALLE   (Colombia)

^e DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

Biopsy; Chronic inflammation; Gastric cancer; Helicobacter; Methylation; Pyrosequencing

Indexed keywords

CAGA PROTEIN; VACUOLATING TOXIN;

ADULT; ARTICLE; ATROPHIC GASTRITIS; BACTERIAL VIRULENCE; CANCER RISK; CELL INFILTRATION; DNA METHYLATION; DYSPLASIA; EN1 GENE; GENE; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; NONHUMAN; PCDH10 GENE; PRECANCER; PROMOTER REGION; PYROSEQUENCING; R SPONDIN FAMILY MEMBER 2 GENE; STOMACH ADENOCARCINOMA; STOMACH BIOPSY; STOMACH MUCOSA; ZINC FINGER PROTEIN OF THE CEREBELLUM 1 GENE; ZNF610 GENE;

HELICOBACTER; HELICOBACTER PYLORI;

BIOPSY; CHRONIC INFLAMMATION; GASTRIC CANCER; HELICOBACTER; METHYLATION; PYROSEQUENCING;

ADENOCARCINOMA; ADULT; DNA METHYLATION; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LEUKOCYTES, MONONUCLEAR; MIDDLE AGED; STOMACH NEOPLASMS; VIRULENCE;

EID: 84887441677     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.26072     Document Type: Article

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