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Volumn 8, Issue 11, 2016, Pages 6811-6825

Tailoring Particle Size of Mesoporous Silica Nanosystem to Antagonize Glioblastoma and Overcome Blood-Brain Barrier

Author keywords

apoptosis; BBB; glioblastoma; mesoporous silica nanosystem; particle size

Indexed keywords

BLOOD; BRAIN; CELL DEATH; CELLS; CHEMOTHERAPY; CYTOLOGY; DISEASES; ENZYME INHIBITION; MACROMOLECULES; MESOPOROUS MATERIALS; NANOPARTICLES; PARTICLE SIZE; SILICA; TISSUE; TUMORS;

EID: 84962054071     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b11730     Document Type: Article
Times cited : (136)

References (51)
  • 4
    • 84866946180 scopus 로고    scopus 로고
    • CD166/Activated Leukocyte Cell Adhesion Molecule is Expressed on Glioblastoma Progenitor Cells and Involved in the Regulation of Tumor Cell Invasion
    • Kijima, N.; Hosen, N.; Kagawa, N.; Hashimoto, N.; Nakano, A.; Fujimoto, Y.; Kinoshita, M.; Sugiyama, H.; Yoshimine, T. CD166/Activated Leukocyte Cell Adhesion Molecule is Expressed on Glioblastoma Progenitor Cells and Involved in the Regulation of Tumor Cell Invasion Neuro Oncol. 2012, 14, 1254-1264 10.1093/neuonc/nor202
    • (2012) Neuro Oncol. , vol.14 , pp. 1254-1264
    • Kijima, N.1    Hosen, N.2    Kagawa, N.3    Hashimoto, N.4    Nakano, A.5    Fujimoto, Y.6    Kinoshita, M.7    Sugiyama, H.8    Yoshimine, T.9
  • 8
    • 84889872057 scopus 로고    scopus 로고
    • Development, Maintenance and Disruption of the Blood-Brain Barrier
    • Obermeier, B.; Daneman, R.; Ransohoff, R. M. Development, Maintenance and Disruption of the Blood-Brain Barrier Nat. Med. 2013, 19, 1584-1596 10.1038/nm.3407
    • (2013) Nat. Med. , vol.19 , pp. 1584-1596
    • Obermeier, B.1    Daneman, R.2    Ransohoff, R.M.3
  • 10
    • 84899443991 scopus 로고    scopus 로고
    • Overcoming the Blood-Brain Barrier for Delivering Drugs into the Brain by Using Adenosine Receptor Nanoagonist
    • Gao, X.; Qian, J.; Zheng, S.; Changyi, Y.; Zhang, J.; Ju, S.; Zhu, J.; Li, C. Overcoming the Blood-Brain Barrier for Delivering Drugs into the Brain by Using Adenosine Receptor Nanoagonist ACS Nano 2014, 8, 3678-3689 10.1021/nn5003375
    • (2014) ACS Nano , vol.8 , pp. 3678-3689
    • Gao, X.1    Qian, J.2    Zheng, S.3    Changyi, Y.4    Zhang, J.5    Ju, S.6    Zhu, J.7    Li, C.8
  • 12
    • 84893465977 scopus 로고    scopus 로고
    • Vasculogenic Mimicry: A Novel Target for Glioma Therapy
    • Chen, Y. S.; Chen, Z. P. Vasculogenic Mimicry: a Novel Target for Glioma Therapy Aizheng 2014, 33, 74-79 10.5732/cjc.012.10292
    • (2014) Aizheng , vol.33 , pp. 74-79
    • Chen, Y.S.1    Chen, Z.P.2
  • 13
    • 84964312658 scopus 로고    scopus 로고
    • Suppressor of Fused (Sufu) Represses Gli1 Transcription and Nuclear Accumulation, Inhibits Glioma Cell Proliferation, Invasion and Vasculogenic Mimicry, Improving Glioma Chemo-Sensitivity and Prognosis
    • Liu, X.; Wang, X.; Du, W.; Chen, L.; Wang, G.; Cui, Y.; Liu, Y.; Dou, Z.; Wang, H.; Zhang, P.; Chang, L.; Yi, L.; Cai, J.; Jiang, C. Suppressor of Fused (Sufu) Represses Gli1 Transcription and Nuclear Accumulation, Inhibits Glioma Cell Proliferation, Invasion and Vasculogenic Mimicry, Improving Glioma Chemo-Sensitivity and Prognosis Oncotarget 2014, 5, 11681-11694 10.18632/oncotarget.2585
    • (2014) Oncotarget , vol.5 , pp. 11681-11694
    • Liu, X.1    Wang, X.2    Du, W.3    Chen, L.4    Wang, G.5    Cui, Y.6    Liu, Y.7    Dou, Z.8    Wang, H.9    Zhang, P.10    Chang, L.11    Yi, L.12    Cai, J.13    Jiang, C.14
  • 14
    • 84879407973 scopus 로고    scopus 로고
    • CDH5 is Specifically Activated in Glioblastoma Stemlike Cells and Contributes to Vasculogenic Mimicry Induced by Hypoxia
    • Mao, X. G.; Xue, X. Y.; Wang, L.; Zhang, X.; Yan, M.; Tu, Y. Y.; Lin, W.; Jiang, X. F.; Ren, H. G.; Zhang, W.; Song, S. J. CDH5 is Specifically Activated in Glioblastoma Stemlike Cells and Contributes to Vasculogenic Mimicry Induced by Hypoxia Neuro Oncol. 2013, 15, 865-879 10.1093/neuonc/not029
    • (2013) Neuro Oncol. , vol.15 , pp. 865-879
    • Mao, X.G.1    Xue, X.Y.2    Wang, L.3    Zhang, X.4    Yan, M.5    Tu, Y.Y.6    Lin, W.7    Jiang, X.F.8    Ren, H.G.9    Zhang, W.10    Song, S.J.11
  • 15
    • 84938613706 scopus 로고    scopus 로고
    • Multifunctional Tandem Peptide Modified Paclitaxel-Loaded Liposomes for the Treatment of Vasculogenic Mimicry and Cancer Stem Cells in Malignant Glioma
    • Liu, Y.; Mei, L.; Yu, Q.; Xu, C.; Qiu, Y.; Yang, Y.; Shi, K.; Zhang, Q.; Gao, H.; Zhang, Z.; He, Q. Multifunctional Tandem Peptide Modified Paclitaxel-Loaded Liposomes for the Treatment of Vasculogenic Mimicry and Cancer Stem Cells in Malignant Glioma ACS Appl. Mater. Interfaces 2015, 7, 16792-16801 10.1021/acsami.5b04596
    • (2015) ACS Appl. Mater. Interfaces , vol.7 , pp. 16792-16801
    • Liu, Y.1    Mei, L.2    Yu, Q.3    Xu, C.4    Qiu, Y.5    Yang, Y.6    Shi, K.7    Zhang, Q.8    Gao, H.9    Zhang, Z.10    He, Q.11
  • 16
    • 34547142222 scopus 로고    scopus 로고
    • Vasculogenic Mimicry: Current Status and Future Prospects
    • Zhang, S.; Zhang, D.; Sun, B. Vasculogenic Mimicry: Current Status and Future Prospects Cancer Lett. 2007, 254, 157-164 10.1016/j.canlet.2006.12.036
    • (2007) Cancer Lett. , vol.254 , pp. 157-164
    • Zhang, S.1    Zhang, D.2    Sun, B.3
  • 17
    • 84877288426 scopus 로고    scopus 로고
    • Liposomes Functionalized to Overcome the Blood-Brain Barrier and to Target Amyloid-Beta Peptide: The Chemical Design Affects the Permeability Across an in Vitro Model
    • Salvati, E.; Re, F.; Sesana, S.; Cambianica, I.; Sancini, G.; Masserini, M.; Gregori, M. Liposomes Functionalized to Overcome the Blood-Brain Barrier and to Target Amyloid-Beta Peptide: the Chemical Design Affects the Permeability Across an In Vitro Model Int. J. Nanomed. 2013, 8, 1749-1758 10.2147/IJN.S42783
    • (2013) Int. J. Nanomed. , vol.8 , pp. 1749-1758
    • Salvati, E.1    Re, F.2    Sesana, S.3    Cambianica, I.4    Sancini, G.5    Masserini, M.6    Gregori, M.7
  • 19
    • 35348882024 scopus 로고    scopus 로고
    • Nanotechnology Applications in Cancer
    • Nie, S.; Xing, Y.; Kim, G. J.; Simons, J. W. Nanotechnology Applications in Cancer Annu. Rev. Biomed. Eng. 2007, 9, 257-288 10.1146/annurev.bioeng.9.060906.152025
    • (2007) Annu. Rev. Biomed. Eng. , vol.9 , pp. 257-288
    • Nie, S.1    Xing, Y.2    Kim, G.J.3    Simons, J.W.4
  • 20
    • 14644439267 scopus 로고    scopus 로고
    • Cancer Nanotechnology: Opportunities and Challenges
    • Ferrari, M. Cancer Nanotechnology: Opportunities and Challenges Nat. Rev. Cancer 2005, 5, 161-171 10.1038/nrc1566
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 24
    • 84892995426 scopus 로고    scopus 로고
    • A Targeted Approach to Cancer Imaging and Therapy
    • Li, C. A Targeted Approach to Cancer Imaging and Therapy Nat. Mater. 2014, 13, 110-115 10.1038/nmat3877
    • (2014) Nat. Mater. , vol.13 , pp. 110-115
    • Li, C.1
  • 25
    • 84885481781 scopus 로고    scopus 로고
    • Self-Assembly of Carbon Nanotubes and Antibodies on Tumours for Targeted Amplified Delivery
    • Mulvey, J. J.; Villa, C. H.; McDevitt, M. R.; Escorcia, F. E.; Casey, E.; Scheinberg, D. A. Self-Assembly of Carbon Nanotubes and Antibodies on Tumours for Targeted Amplified Delivery Nat. Nanotechnol. 2013, 8, 763-771 10.1038/nnano.2013.190
    • (2013) Nat. Nanotechnol. , vol.8 , pp. 763-771
    • Mulvey, J.J.1    Villa, C.H.2    McDevitt, M.R.3    Escorcia, F.E.4    Casey, E.5    Scheinberg, D.A.6
  • 26
    • 34249780352 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications
    • Slowing, I. I.; Trewyn, B. G.; Giri, S.; Lin, V. S. Y. Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications Adv. Funct. Mater. 2007, 17, 1225-1236 10.1002/adfm.200601191
    • (2007) Adv. Funct. Mater. , vol.17 , pp. 1225-1236
    • Slowing, I.I.1    Trewyn, B.G.2    Giri, S.3    Lin, V.S.Y.4
  • 27
    • 0038457473 scopus 로고    scopus 로고
    • Molecular Plasticity of Human Melanoma Cells
    • Hendrix, M. J.; Seftor, E. A.; Hess, A. R.; Seftor, R. E. Molecular Plasticity of Human Melanoma Cells Oncogene 2003, 22, 3070-3075 10.1038/sj.onc.1206447
    • (2003) Oncogene , vol.22 , pp. 3070-3075
    • Hendrix, M.J.1    Seftor, E.A.2    Hess, A.R.3    Seftor, R.E.4
  • 28
    • 81955167365 scopus 로고    scopus 로고
    • Nanoliposome-Mediated FL/TRAIL Double-Gene Therapy for Colon Cancer: In Vitro and in Vivo Evaluation
    • Sun, N. F.; Meng, Q. Y.; Tian, A. L.; Hu, S. Y.; Wang, R. H.; Liu, Z. X.; Xu, L. Nanoliposome-Mediated FL/TRAIL Double-Gene Therapy for Colon Cancer: In Vitro and In Vivo Evaluation Cancer Lett. 2012, 315, 69-77 10.1016/j.canlet.2011.10.010
    • (2012) Cancer Lett. , vol.315 , pp. 69-77
    • Sun, N.F.1    Meng, Q.Y.2    Tian, A.L.3    Hu, S.Y.4    Wang, R.H.5    Liu, Z.X.6    Xu, L.7
  • 29
  • 30
    • 84892533825 scopus 로고    scopus 로고
    • MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition
    • He, Q.; Shi, J. MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition Adv. Mater. 2014, 26, 391-411 10.1002/adma.201303123
    • (2014) Adv. Mater. , vol.26 , pp. 391-411
    • He, Q.1    Shi, J.2
  • 31
    • 84879108339 scopus 로고    scopus 로고
    • In Vivo Bio-safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles
    • Chen, Y.; Chen, H.; Shi, J. In Vivo Bio-safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles Adv. Mater. 2013, 25, 3144-3176 10.1002/adma.201205292
    • (2013) Adv. Mater. , vol.25 , pp. 3144-3176
    • Chen, Y.1    Chen, H.2    Shi, J.3
  • 32
    • 84900854455 scopus 로고    scopus 로고
    • Cancer-Targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects
    • He, L.; Huang, Y.; Zhu, H.; Pang, G.; Zheng, W.; Wong, Y.-S.; Chen, T. Cancer-Targeted Monodisperse Mesoporous Silica Nanoparticles as Carrier of Ruthenium Polypyridyl Complexes to Enhance Theranostic Effects Adv. Funct. Mater. 2014, 24, 2754-2763 10.1002/adfm.201303533
    • (2014) Adv. Funct. Mater. , vol.24 , pp. 2754-2763
    • He, L.1    Huang, Y.2    Zhu, H.3    Pang, G.4    Zheng, W.5    Wong, Y.-S.6    Chen, T.7
  • 33
    • 84915767305 scopus 로고    scopus 로고
    • A Cancer-Targeted Nanosystem for Delivery of Gold(III) Complexes: Enhanced Selectivity and Apoptosis-Inducing Efficacy of a Gold(III) Porphyrin Complex
    • He, L.; Chen, T.; You, Y.; Hu, H.; Zheng, W.; Kwong, W. L.; Zou, T.; Che, C. M. A Cancer-Targeted Nanosystem for Delivery of Gold(III) Complexes: Enhanced Selectivity and Apoptosis-Inducing Efficacy of a Gold(III) Porphyrin Complex Angew. Chem., Int. Ed. 2014, 53, 12532-12536 10.1002/anie.201407143
    • (2014) Angew. Chem., Int. Ed. , vol.53 , pp. 12532-12536
    • He, L.1    Chen, T.2    You, Y.3    Hu, H.4    Zheng, W.5    Kwong, W.L.6    Zou, T.7    Che, C.M.8
  • 34
    • 84861235902 scopus 로고    scopus 로고
    • Dissociation Constants of Protonated Amines in Water at Temperatures from 293.15 to 343.15 K
    • Simond, M. R.; Ballerat-Busserolles, K.; Coulier, Y.; Rodier, L.; Coxam, J. Y. Dissociation Constants of Protonated Amines in Water at Temperatures from 293.15 to 343.15 K J. Solution Chem. 2012, 41, 130-142 10.1007/s10953-011-9790-3
    • (2012) J. Solution Chem. , vol.41 , pp. 130-142
    • Simond, M.R.1    Ballerat-Busserolles, K.2    Coulier, Y.3    Rodier, L.4    Coxam, J.Y.5
  • 36
    • 84855851289 scopus 로고    scopus 로고
    • In Vivo Tumor Suppression Efficacy of Mesoporous Silica Nanoparticles-Based Drug-Delivery System: Enhanced Efficacy by Folate Modification
    • Lu, J.; Li, Z.; Zink, J. I.; Tamanoi, F. In Vivo Tumor Suppression Efficacy of Mesoporous Silica Nanoparticles-Based Drug-Delivery System: Enhanced Efficacy by Folate Modification Nanomedicine 2012, 8, 212-220 10.1016/j.nano.2011.06.002
    • (2012) Nanomedicine , vol.8 , pp. 212-220
    • Lu, J.1    Li, Z.2    Zink, J.I.3    Tamanoi, F.4
  • 37
    • 84860386423 scopus 로고    scopus 로고
    • Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood-Brain Barrier
    • Qiao, R.; Jia, Q.; Huwel, S.; Xia, R.; Liu, T.; Gao, F.; Galla, H.-J.; Gao, M. Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood-Brain Barrier ACS Nano 2012, 6, 3304-3310 10.1021/nn300240p
    • (2012) ACS Nano , vol.6 , pp. 3304-3310
    • Qiao, R.1    Jia, Q.2    Huwel, S.3    Xia, R.4    Liu, T.5    Gao, F.6    Galla, H.-J.7    Gao, M.8
  • 38
    • 84896493907 scopus 로고    scopus 로고
    • Paclitaxel Loaded Liposomes Decorated with a Multifunctional Tandem Peptide for Glioma Targeting
    • Liu, Y.; Ran, R.; Chen, J.; Kuang, Q.; Tang, J.; Mei, L.; Zhang, Q.; Gao, H.; Zhang, Z.; He, Q. Paclitaxel Loaded Liposomes Decorated With a Multifunctional Tandem Peptide for Glioma Targeting Biomaterials 2014, 35, 4835-4847 10.1016/j.biomaterials.2014.02.031
    • (2014) Biomaterials , vol.35 , pp. 4835-4847
    • Liu, Y.1    Ran, R.2    Chen, J.3    Kuang, Q.4    Tang, J.5    Mei, L.6    Zhang, Q.7    Gao, H.8    Zhang, Z.9    He, Q.10
  • 39
    • 84862812503 scopus 로고    scopus 로고
    • Co-delivery of TRAIL Gene Enhances the Anti-Glioblastoma Effect of Paclitaxel in Vitro and in Vivo
    • Zhan, C.; Wei, X.; Qian, J.; Feng, L.; Zhu, J.; Lu, W. Co-delivery of TRAIL Gene Enhances the Anti-Glioblastoma Effect of Paclitaxel In Vitro and In Vivo J. Controlled Release 2012, 160, 630-636 10.1016/j.jconrel.2012.02.022
    • (2012) J. Controlled Release , vol.160 , pp. 630-636
    • Zhan, C.1    Wei, X.2    Qian, J.3    Feng, L.4    Zhu, J.5    Lu, W.6
  • 40
    • 84912112177 scopus 로고    scopus 로고
    • Enhanced BBB Permeability of Osmotically Active Poly(mannitol-co-PEI) Modified with Rabies Virus Glycoprotein via Selective Stimulation of Caveolar Endocytosis for RNAi Therapeutics in Alzheimer's disease
    • Park, T. E.; Singh, B.; Li, H.; Lee, J. Y.; Kang, S. K.; Choi, Y. J.; Cho, C. S. Enhanced BBB Permeability of Osmotically Active Poly(mannitol-co-PEI) Modified with Rabies Virus Glycoprotein via Selective Stimulation of Caveolar Endocytosis for RNAi Therapeutics in Alzheimer's disease Biomaterials 2015, 38, 61-71 10.1016/j.biomaterials.2014.10.068
    • (2015) Biomaterials , vol.38 , pp. 61-71
    • Park, T.E.1    Singh, B.2    Li, H.3    Lee, J.Y.4    Kang, S.K.5    Choi, Y.J.6    Cho, C.S.7
  • 41
    • 84865576604 scopus 로고    scopus 로고
    • Selenium Nanoparticles as a Carrier of 5-fluorouracil to Achieve Anticancer Synergism
    • Liu, W.; Li, X.; Wong, Y. S.; Zheng, W.; Zhang, Y.; Cao, W.; Chen, T. Selenium Nanoparticles as a Carrier of 5-fluorouracil to Achieve Anticancer Synergism ACS Nano 2012, 6, 6578-6591 10.1021/nn202452c
    • (2012) ACS Nano , vol.6 , pp. 6578-6591
    • Liu, W.1    Li, X.2    Wong, Y.S.3    Zheng, W.4    Zhang, Y.5    Cao, W.6    Chen, T.7
  • 42
    • 84924911894 scopus 로고    scopus 로고
    • Dual-Function Nanosystem for Synergetic Cancer Chemo-/Radiotherapy through ROS-Mediated Signaling Pathways
    • He, L.; Lai, H.; Chen, T. Dual-Function Nanosystem for Synergetic Cancer Chemo-/Radiotherapy through ROS-Mediated Signaling Pathways Biomaterials 2015, 51, 30-42 10.1016/j.biomaterials.2015.01.063
    • (2015) Biomaterials , vol.51 , pp. 30-42
    • He, L.1    Lai, H.2    Chen, T.3
  • 43
    • 51349139834 scopus 로고    scopus 로고
    • Selenocystine Induces Apoptosis of A375 Human Melanoma Cells by Activating ROS-Mediated Mitochondrial Pathway and p53 Phosphorylation
    • Chen, T.; Wong, Y. S. Selenocystine Induces Apoptosis of A375 Human Melanoma Cells by Activating ROS-Mediated Mitochondrial Pathway and p53 Phosphorylation Cell. Mol. Life Sci. 2008, 65, 2763-2775 10.1007/s00018-008-8329-2
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 2763-2775
    • Chen, T.1    Wong, Y.S.2
  • 44
    • 58949088847 scopus 로고    scopus 로고
    • Selenocystine Induces Reactive Oxygen Species-Mediated Apoptosis in Human Cancer Cells
    • Chen, T.; Wong, Y. S. Selenocystine Induces Reactive Oxygen Species-Mediated Apoptosis in Human Cancer Cells Biomed. Pharmacother. 2009, 63, 105-113 10.1016/j.biopha.2008.03.009
    • (2009) Biomed. Pharmacother. , vol.63 , pp. 105-113
    • Chen, T.1    Wong, Y.S.2
  • 45
    • 57849084052 scopus 로고    scopus 로고
    • Selenocystine Induces S-Phase Arrest and Apoptosis in Human Breast Adenocarcinoma MCF-7 Cells by Modulating ERK and Akt Phosphorylation
    • Chen, T.; Wong, Y. S. Selenocystine Induces S-Phase Arrest and Apoptosis in Human Breast Adenocarcinoma MCF-7 Cells by Modulating ERK and Akt Phosphorylation J. Agric. Food Chem. 2008, 56, 10574-10581 10.1021/jf802125t
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 10574-10581
    • Chen, T.1    Wong, Y.S.2
  • 47
    • 84960433266 scopus 로고    scopus 로고
    • Strategies to Improve Delivery of Anticancer Drugs Across the Blood-Brain Barrier to Treat Glioblastoma
    • Oberoi, R. K.; Parrish, K. E.; Sio, T. T.; Mittapalli, R. K.; Elmquist, W. F.; Sarkaria, J. N. Strategies to Improve Delivery of Anticancer Drugs Across the Blood-Brain Barrier to Treat Glioblastoma Neuro Oncol. 2016, 18, 27-36 10.1093/neuonc/nov164
    • (2016) Neuro Oncol. , vol.18 , pp. 27-36
    • Oberoi, R.K.1    Parrish, K.E.2    Sio, T.T.3    Mittapalli, R.K.4    Elmquist, W.F.5    Sarkaria, J.N.6
  • 48
    • 84864456950 scopus 로고    scopus 로고
    • Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug
    • Lee, M. H.; Kim, J. Y.; Han, J. H.; Bhuniya, S.; Sessler, J. L.; Kang, C.; Kim, J. S. Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug J. Am. Chem. Soc. 2012, 134, 12668-12674 10.1021/ja303998y
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 12668-12674
    • Lee, M.H.1    Kim, J.Y.2    Han, J.H.3    Bhuniya, S.4    Sessler, J.L.5    Kang, C.6    Kim, J.S.7
  • 49
    • 84950121603 scopus 로고    scopus 로고
    • Endocytosis of Ligand Activated Sphingosine 1-Phosphate Receptor 1 Mediated by the Clathrin-pathway
    • Reeves, P. M.; Kang, Y. L.; Kirchhausen, T. Endocytosis of Ligand Activated Sphingosine 1-Phosphate Receptor 1 Mediated by the Clathrin-pathway Traffic 2016, 17, 40-52 10.1111/tra.12343
    • (2016) Traffic , vol.17 , pp. 40-52
    • Reeves, P.M.1    Kang, Y.L.2    Kirchhausen, T.3
  • 50
    • 84880994920 scopus 로고    scopus 로고
    • Selenocystine PotentiatesCancer Cell Apoptosis Induced by 5-Fluorouracil by Triggering Reactive Oxygen Species-Mediated DNA Damage and Inactivation of the ERK Pathway
    • Fan, C.; Chen, J.; Wang, Y.; Wong, Y. S.; Zhang, Y.; Zheng, W.; Cao, W.; Chen, T. Selenocystine PotentiatesCancer Cell Apoptosis Induced by 5-Fluorouracil by Triggering Reactive Oxygen Species-Mediated DNA Damage and Inactivation of the ERK Pathway Free Radical Biol. Med. 2013, 65, 305-316 10.1016/j.freeradbiomed.2013.07.002
    • (2013) Free Radical Biol. Med. , vol.65 , pp. 305-316
    • Fan, C.1    Chen, J.2    Wang, Y.3    Wong, Y.S.4    Zhang, Y.5    Zheng, W.6    Cao, W.7    Chen, T.8


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