Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior

Arthritis and Rheumatology

Volumn 68, Issue 4, 2016, Pages 857-867

  Driscoll, Clare ^a   Chanalaris, Anastasios ^a   Knights, Chancie ^b   Ismail, Heba ^a   Sacitharan, Pradeep K ^a   Gentry, Clive ^b   Bevan, Stuart ^b   Vincent, Tonia L ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; CD14 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR7; FIBROBLAST GROWTH FACTOR 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6 RECEPTOR ALPHA; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MYELOID DIFFERENTIATION FACTOR 88; NERVE GROWTH FACTOR; PHOSPHOTRANSFERASE; PROTEIN P75; RNA; SRC KINASE; TACHYKININ; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR 1; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NEUROKININ 1 RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BEHAVIOR ASSESSMENT; BIOMECHANICS; CARTILAGE INJURY; COLD PLATE TEST; COLD SENSITIVITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FORCED FLEXION TESTING; GENE EXPRESSION; INCAPACITANCE TESTING; JOINT INJURY; JOINT INSTABILITY; JOINT TISSUE DAMAGE; KNEE MENISCUS; LEUKOCYTE ACTIVATION; MALE; MECHANICAL HYPERALGESIA; MENISCECTOMY; MOUSE; NOCICEPTION; NONHUMAN; OSTEOARTHRITIS; PAIN; PIG; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SRC HOMOLOGY DOMAIN; VON FREY TEST; ANIMAL; BONE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; INJURIES; KNEE OSTEOARTHRITIS; METABOLISM; NOCICEPTIVE PAIN;

ANIMALS; BEHAVIOR, ANIMAL; BONE AND BONES; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; MAP KINASE KINASE KINASES; MENISCI, TIBIAL; MICE; NERVE GROWTH FACTOR; NOCICEPTIVE PAIN; OSTEOARTHRITIS, KNEE; PAIN; RECEPTOR, BRADYKININ B1; RECEPTOR, BRADYKININ B2; RECEPTORS, NEUROKININ-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SRC-FAMILY KINASES; SWINE; TACHYKININS;

EID: 84962045510     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39523     Document Type: Article

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