-
1
-
-
84870688010
-
Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
-
Orsenigo F, Giampietro C, Ferrari A, Corada M, Galaup A, et al (2012) Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat Commun 3: 1208.
-
(2012)
Nat Commun
, vol.3
, pp. 1208
-
-
Orsenigo, F.1
Giampietro, C.2
Ferrari, A.3
Corada, M.4
Galaup, A.5
-
2
-
-
84855876062
-
Bradykinin receptor 2 extends inflammatory cell recruitment in a model of acute gouty arthritis
-
Shaw OM, Harper JL (2011) Bradykinin receptor 2 extends inflammatory cell recruitment in a model of acute gouty arthritis. Biochem Biophys Res Commun 416: 266-9.
-
(2011)
Biochem Biophys Res Commun
, vol.416
, pp. 266-269
-
-
Shaw, O.M.1
Harper, J.L.2
-
3
-
-
17144475047
-
Bradykinin antagonists in human systems: Correlation between receptor binding, calcium signalling in isolated cells, and functional activity in isolated ileum
-
DOI 10.1016/S0006-2952(97)00186-X, PII S000629529700186X
-
Wieczorek M, Pilyawskaya A, Burkard M, Zuzack JS, Jones SW, et al (1997). Bradykinin Antagonists in human systems: correlation between receptor binding, calcium signalling in isolated cells, and functional activity in isolated ileum. Biochemical Pharmacology 54: 283-291. (Pubitemid 27357005)
-
(1997)
Biochemical Pharmacology
, vol.54
, Issue.2
, pp. 283-291
-
-
Wieczorek, M.1
Pilyavskaya, A.2
Burkard, M.3
Zuzack, J.S.4
Jones, S.W.5
Francis, M.D.6
Beckey, V.E.7
Ross, S.E.8
Goodfellow, V.S.9
Fitzpatrick, T.D.10
Marathe, M.V.11
Gyorkos, A.12
Spruce, L.W.13
Selig, W.M.14
Stewart, J.M.15
Gera, L.16
Whalley, E.T.17
-
4
-
-
0031874006
-
B1 receptor involvement in the effect of bradykinin on venular endothelial cell proliferation and potentiation of FGF-2 effects
-
DOI 10.1038/sj.bjp.0701943
-
Morbidelli L, Parenti A, Giovannelli L, Granger HJ, Ledda F, et al (1998) B1 receptor involvement in the effect of bradykinin on venular endothelial cell proliferation and potentiation of FGF-2 effects. Br J Pharmacol 124: 1286-1292. (Pubitemid 28333954)
-
(1998)
British Journal of Pharmacology
, vol.124
, Issue.6
, pp. 1286-1292
-
-
Morbidelli, L.1
Parenti, A.2
Giovannelli, L.3
Granger, H.J.4
Ledda, F.5
Ziche, M.6
-
5
-
-
0035379715
-
The bradykinin/B1 receptor promotes angiogenesis by up-regulation of endogenous FGF-2 in endothelium via the nitric oxide synthase pathway
-
Parenti A, Morbidelli L, Ledda F, Granger HJ, Ziche M (2001) The bradykinin/B1 receptor promotes angiogenesis by up-regulation of endogenous FGF-2 in endothelium via the nitric oxide synthase pathway. FASEB J 15: 1487-98.
-
(2001)
FASEB J
, vol.15
, pp. 1487-1498
-
-
Parenti, A.1
Morbidelli, L.2
Ledda, F.3
Granger, H.J.4
Ziche, M.5
-
6
-
-
0035986330
-
2 antagonists and bradykinin-induced blood flow in rat skin inflammation
-
Cao T, Brain SD, Khodr B, Khalil Z (2002) B1 and B2 antagonists and bradykinin-induced blood flow in rat skin inflammation. Inflamm Res 51: 295-9. (Pubitemid 34628032)
-
(2002)
Inflammation Research
, vol.51
, Issue.6
, pp. 295-299
-
-
Cao, T.1
Brain, S.D.2
Khodr, B.3
Khalil, Z.4
-
7
-
-
84869834694
-
Clinical efficacy of icatibant in the treatment of acute hereditary angioedema during the FAST-3 trial
-
Bas M (2012) Clinical efficacy of icatibant in the treatment of acute hereditary angioedema during the FAST-3 trial. Expert Rev Clin Immunol 8: 707-17.
-
(2012)
Expert Rev Clin Immunol
, vol.8
, pp. 707-717
-
-
Bas, M.1
-
8
-
-
0030805903
-
Generation of kinins in synovial fluid from patients with arthropathy
-
DOI 10.1016/S0162-3109(97)00023-4, PII S0162310997000234
-
Bond AP, Lemon M, Dieppe PA, Bhoola KD (1997) Generation of kinins in synovial fluid from patients with arthropathy. Immunopharmacol 36: 209-216. (Pubitemid 27286323)
-
(1997)
Immunopharmacology
, vol.36
, Issue.2-3
, pp. 209-216
-
-
Bond, A.P.1
Lemon, M.2
Dieppe, P.A.3
Bhoola, K.D.4
-
9
-
-
51749089329
-
Knee osteoarthritis: A role for bradykinin?
-
Meini S, Maggi CA (2008) Knee osteoarthritis: a role for bradykinin? Inflamm Res 57: 351-61.
-
(2008)
Inflamm Res
, vol.57
, pp. 351-361
-
-
Meini, S.1
Maggi, C.A.2
-
10
-
-
71749085325
-
Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts
-
Bellucci F, Cucchi P, Catalani C, Giuliani S, Meini S, et al (2009) Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts. Br J Pharmacol 158: 1996-2004.
-
(2009)
Br J Pharmacol
, vol.158
, pp. 1996-2004
-
-
Bellucci, F.1
Cucchi, P.2
Catalani, C.3
Giuliani, S.4
Meini, S.5
-
11
-
-
78651458938
-
Bradykinin and B(2) receptor antagonism in rat and human articular chondrocytes
-
Meini S, Cucchi P, Catalani C, Bellucci F, Giuliani S, et al (2011a) Bradykinin and B(2) receptor antagonism in rat and human articular chondrocytes. Br J Pharmacol 162: 611-622.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 611-622
-
-
Meini, S.1
Cucchi, P.2
Catalani, C.3
Bellucci, F.4
Giuliani, S.5
-
12
-
-
14144251086
-
International union of pharmacology. XLV. Classification of the kinin receptor family: From molecular mechanisms to pathophysiological consequences
-
DOI 10.1124/pr.57.1.2
-
Leeb-Lundberg LM, Marceau F, Muller-Esterl W, Pettibone DJ, Zuraw BL (2005) International union of pharmacology XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev 57: 27-77. (Pubitemid 40283969)
-
(2005)
Pharmacological Reviews
, vol.57
, Issue.1
, pp. 27-77
-
-
Leeb-Lundberg, L.M.F.1
Marceau, F.2
Muller-Esterl, W.3
Pettibone, D.J.4
Zuraw, B.L.5
-
13
-
-
67650422046
-
Bradykinin receptor antagonists-a review of the patent literature 2005-2008
-
Fincham CI, Bressan A, Paris M, Rossi C, Fattori D (2009) Bradykinin receptor antagonists-a review of the patent literature 2005-2008. Expert Opin Ther Pat 19: 919-41.
-
(2009)
Expert Opin Ther Pat
, vol.19
, pp. 919-941
-
-
Fincham, C.I.1
Bressan, A.2
Paris, M.3
Rossi, C.4
Fattori, D.5
-
14
-
-
84866486488
-
Icatibant, the bradykinin B2 receptor antagonist with target to the interconnected kinin systems
-
Charignon D, Späth P, Martin L, Drouet C (2012) Icatibant, the bradykinin B2 receptor antagonist with target to the interconnected kinin systems. Expert Opin Pharmacother 13: 2233-47.
-
(2012)
Expert Opin Pharmacother
, vol.13
, pp. 2233-2247
-
-
Charignon, D.1
Späth, P.2
Martin, L.3
Drouet, C.4
-
15
-
-
28844459058
-
2 receptor. In vitro pharmacology and molecular characterization
-
DOI 10.1016/j.ejphar.2005.10.014, PII S0014299905010721
-
Cucchi P, Meini S, Bressan A, Catalani C, Bellucci F, et al (2005) MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology andmolecular characterization. Eur J Pharmacol 528:7-16. (Pubitemid 41773646)
-
(2005)
European Journal of Pharmacology
, vol.528
, Issue.1-3
, pp. 7-16
-
-
Cucchi, P.1
Meini, S.2
Bressan, A.3
Catalani, C.4
Bellucci, F.5
Santicioli, P.6
Lecci, A.7
Faiella, A.8
Rotondaro, L.9
Giuliani, S.10
Giolitti, A.11
Quartara, L.12
Maggi, C.A.13
-
16
-
-
33846874995
-
2 receptor: Radioligand binding and smooth muscle contractility studies
-
DOI 10.1038/sj.bjp.0706995, PII 0706995
-
Meini S, Cucchi P, Bellucci F, Catalani C, Giuliani S, et al (2007) Comparative antagonist pharmacology at the native mouse bradykinin B2 receptor: radioligand binding and smooth muscle contractility studies. Br J Pharmacol 150: 313-20. (Pubitemid 46221040)
-
(2007)
British Journal of Pharmacology
, vol.150
, Issue.3
, pp. 313-320
-
-
Meini, S.1
Cucchi, P.2
Bellucci, F.3
Catalani, C.4
Giuliani, S.5
Santicioli, P.6
Maggi, C.A.7
-
17
-
-
67449155882
-
Pharmacological characterization of the bradykinin B2 receptor antagonist MEN16132 in rat in vitro bioassays
-
Meini S, Cucchi P, Catalani C, Bellucci F, Giuliani S, P etal (2009) Pharmacological characterization of the bradykinin B2 receptor antagonist MEN16132 in rat in vitro bioassays. Eur J Pharmacol 615: 10-6.
-
(2009)
Eur J Pharmacol
, vol.615
, pp. 10-16
-
-
Meini, S.1
Cucchi, P.2
Catalani, C.3
Bellucci, F.4
Giuliani, S.P.E.5
-
18
-
-
77952322087
-
Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle
-
Meini S, Cucchi P, Catalani C, Bellucci F, Santicioli P, et al (2010) Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle. Eur J Pharmacol 635: 34-9.
-
(2010)
Eur J Pharmacol
, vol.635
, pp. 34-39
-
-
Meini, S.1
Cucchi, P.2
Catalani, C.3
Bellucci, F.4
Santicioli, P.5
-
19
-
-
37649008332
-
MEN16132, a kinin B2 receptor antagonist, prevents the endogenous bradykinin effects in guinea-pig airways
-
Valenti C, Cialdai C, Giuliani S, Tramontana M, Quartara L, et al (2008) MEN16132, a kinin B2 receptor antagonist, prevents the endogenous bradykinin effects in guinea-pig airways. Eur J Pharmacol 579: 350-6.
-
(2008)
Eur J Pharmacol
, vol.579
, pp. 350-356
-
-
Valenti, C.1
Cialdai, C.2
Giuliani, S.3
Tramontana, M.4
Quartara, L.5
-
20
-
-
78149399009
-
Anti-inflammatory synergy of MEN16132, a kinin B2 receptor antagonist, and dexamethasone in carrageenan-induced knee joint arthritis in rats
-
Valenti C, Giuliani S, Cialdai C, Tramontana M, Maggi CA (2010) Anti-inflammatory synergy of MEN16132, a kinin B2 receptor antagonist, and dexamethasone in carrageenan-induced knee joint arthritis in rats. Br J Pharmacol 161: 1616-27.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 1616-1627
-
-
Valenti, C.1
Giuliani, S.2
Cialdai, C.3
Tramontana, M.4
Maggi, C.A.5
-
21
-
-
73349129369
-
Effect of Intra-articular4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4- dimethyl-8-quinolyloxymethyl) phenylsulfo namido]-tetrahydro-2H-4- pyranylcarbonyl piperazino)-5-oxopentyl(trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats
-
Cialdai C, Giuliani S, Valenti C, Tramontana M, Maggi CA (2009) Effect of Intra-articular4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8- quinolyloxymethyl) phenylsulfo namido]-tetrahydro-2H-4-pyranylcarbonyl] piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats. J Pharmacol Exp Ther 331: 1025-32.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 1025-1032
-
-
Cialdai, C.1
Giuliani, S.2
Valenti, C.3
Tramontana, M.4
Maggi, C.A.5
-
22
-
-
84882733403
-
Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant
-
Gomis A, Meini S, Miralles A, Valenti C, Giuliani S, et al, (2013) Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant. Osteoarthritis Cartilage 21: 1346-1354.
-
(2013)
Osteoarthritis Cartilage
, vol.21
, pp. 1346-1354
-
-
Gomis, A.1
Meini, S.2
Miralles, A.3
Valenti, C.4
Giuliani, S.5
-
24
-
-
0043074681
-
Inflammation and angiogenesis in osteoarthritis
-
DOI 10.1002/art.11094
-
Haywood L, McWilliams DF, Pearson CI, Gill SE, Ganesan A, et al (2003) Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum 48: 2173-7. (Pubitemid 36959197)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.8
, pp. 2173-2177
-
-
Haywood, L.1
McWilliams, D.F.2
Pearson, C.I.3
Gill, S.E.4
Ganesan, A.5
Wilson, D.6
Walsh, D.A.7
-
25
-
-
34250212488
-
Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis
-
DOI 10.1016/j.joca.2007.01.020, PII S1063458407000581
-
Walsh DA, Bonnet CS, Turner EL, Wilson D, Situ M, et al (2007) Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis. Osteoarthritis Cartilage 15: 743-51. (Pubitemid 46893968)
-
(2007)
Osteoarthritis and Cartilage
, vol.15
, Issue.7
, pp. 743-751
-
-
Walsh, D.A.1
Bonnet, C.S.2
Turner, E.L.3
Wilson, D.4
Situ, M.5
McWilliams, D.F.6
-
26
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407: 249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
27
-
-
79751535384
-
Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells
-
Spinetti G, Fortunato O, Cordella D, Portararo P, Kränkel N, et al (2011) Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells. Circ Res 108: 284-93.
-
(2011)
Circ Res
, vol.108
, pp. 284-293
-
-
Spinetti, G.1
Fortunato, O.2
Cordella, D.3
Portararo, P.4
Kränkel, N.5
-
28
-
-
0342903238
-
Wound healing following myocardial infarction in the rat: Role for bradykinin and prostaglandins
-
Frimm Cde, Sun Y, Weber KT (1996) Wound healing following myocardial infarction in the rat: role for bradykinin and prostaglandins. J. Mol. Cell Cardiol. 28: 1279-1285.
-
(1996)
J. Mol. Cell Cardiol.
, vol.28
, pp. 1279-1285
-
-
Cde, F.1
Sun, Y.2
Weber, K.T.3
-
29
-
-
25644449640
-
Pathophysiological consequences of VEGF-induced vascular permeability
-
DOI 10.1038/nature03987, PII N03987
-
Weis SM, Cheresh DA (2005) Pathophysiological consequences of VEGF-induced vascular permeability. Nature 437: 497-504. (Pubitemid 41613541)
-
(2005)
Nature
, vol.437
, Issue.7058
, pp. 497-504
-
-
Weis, S.M.1
Cheresh, D.A.2
-
30
-
-
48649101326
-
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
-
Taddei A, Giampietro C, Conti A, Orsenigo F, Breviario F, et al (2008) Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Nat Cell Biol 10: 923-34.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 923-934
-
-
Taddei, A.1
Giampietro, C.2
Conti, A.3
Orsenigo, F.4
Breviario, F.5
-
31
-
-
34748914299
-
Evolving functions of endothelial cells in inflammation
-
DOI 10.1038/nri2171, PII NRI2171
-
Pober JS, Sessa WC (2007) Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7: 803-15. (Pubitemid 47480307)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 803-815
-
-
Pober, J.S.1
Sessa, W.C.2
-
32
-
-
70349682610
-
Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway
-
Finetti F, Donnini S, Giachetti A, Morbidelli L, Ziche M (2009) Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway. Circ Res 105: 657-66.
-
(2009)
Circ Res
, vol.105
, pp. 657-666
-
-
Finetti, F.1
Donnini, S.2
Giachetti, A.3
Morbidelli, L.4
Ziche, M.5
-
33
-
-
79551503731
-
Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B2 receptor
-
Meini S, Bellucci F, Catalani C, Cucchi P, Giolitti A, et al (2011b) Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B2 receptor. Br J Pharmacol 162: 1202-1212.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 1202-1212
-
-
Meini, S.1
Bellucci, F.2
Catalani, C.3
Cucchi, P.4
Giolitti, A.5
-
34
-
-
0030615201
-
Nuclear factor-kappaB - A pivotal transcription factor in chronic inflammatory diseases
-
DOI 10.1056/NEJM199704103361506
-
Barnes PJ, Karin M (1997) Nuclear factor-kappa B: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336: 1066-1071. (Pubitemid 27163860)
-
(1997)
New England Journal of Medicine
, vol.336
, Issue.15
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
36
-
-
84870170090
-
Endothelial nuclear factor-kB-dependent regulation of arteriogenesis and branching
-
Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, et al (2012) Endothelial nuclear factor-kB-dependent regulation of arteriogenesis and branching. Circulation 126: 2589-600.
-
(2012)
Circulation
, vol.126
, pp. 2589-2600
-
-
Tirziu, D.1
Jaba, I.M.2
Yu, P.3
Larrivée, B.4
Coon, B.G.5
-
37
-
-
0030614336
-
1 kinin receptor expression and pharmacology in endothelial cells of different origins and species
-
Wohlfart P, Dedio J, Wirth K, Schölkens BA, Wiemer G (1997) Different B1 kinin receptor expression and pharmacology in endothelial cells of different origins and species. J Pharmacol Exp Ther 280: 1109-16. (Pubitemid 27171379)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.280
, Issue.2
, pp. 1109-1116
-
-
Wohlfart, P.1
Dedio, J.2
Wirth, K.3
Scholkens, B.A.4
Wiemer, G.5
-
38
-
-
77954446968
-
Abeta peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis
-
Donnini S, Solito R, Cetti E, Corti F, Giachetti A, et al (2010) Abeta peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis. FASEB J 24: 2385-95.
-
(2010)
FASEB J
, vol.24
, pp. 2385-2395
-
-
Donnini, S.1
Solito, R.2
Cetti, E.3
Corti, F.4
Giachetti, A.5
|