Enantiodivergent Fluorination of Allylic Alcohols: Data Set Design Reveals Structural Interplay between Achiral Directing Group and Chiral Anion

Journal of the American Chemical Society

Volumn 138, Issue 11, 2016, Pages 3863-3875

  Neel, Andrew J ^a   Milo, Anat ^b,c   Sigman, Matthew S ^b   Toste, F Dean ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; ENANTIOSELECTIVITY; FLUORINATION; FLUORINE; FREE ENERGY; HALOGENATION; PHOSPHORIC ACID; STATISTICS; SUBSTRATES;

ARYL BORONIC ACIDS; ENANTIOSELECTION; ENERGY RELATIONSHIPS; HIGH ENANTIOSELECTIVITY; MECHANISTIC STUDIES; MULTIVARIATE CORRELATION; STRUCTURAL FEATURE; STRUCTURAL ORIGIN;

ENANTIOMERS;

ALCOHOL DERIVATIVE; ALLYL COMPOUND; BORONIC ACID DERIVATIVE; PHOSPHORIC ACID; ALLYL ALCOHOL; ANION; FLUORINATED HYDROCARBON; PROPANOL;

ARTICLE; CATALYST; CHIRALITY; COLUMN CHROMATOGRAPHY; ENANTIOSELECTIVITY; EQUILIBRIUM CONSTANT; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL MODEL; NONLINEAR SYSTEM; NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THIN LAYER CHROMATOGRAPHY; CHEMISTRY; INFORMATION PROCESSING; MOLECULAR MODEL; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

ANIONS; DATASETS AS TOPIC; HYDROCARBONS, FLUORINATED; MODELS, MOLECULAR; PROPANOLS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84962045450     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b00356     Document Type: Article

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