"True" chirality transfer from silicon to carbon: Asymmetric amplification in a reagent-controlled palladium-catalyzed hydrosilylation

Angewandte Chemie - International Edition

Volumn 44, Issue 11, 2005, Pages 1661-1664

  Oestreich, Martin ^a   Rendler, Sebastian ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Asymmetric amplification; Asymmetric catalysis; Hydrosilylation; Palladium; Silicon

Indexed keywords

CARBON; CATALYSIS; CATALYSTS; MOLECULAR STRUCTURE; OLEFINS; PALLADIUM; STEREOCHEMISTRY;

CHIRALITY TRANSFER; HYDROSYLATION; PROCHIRAL ALKENES;

SILICON;

EID: 17044375112     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200462355     Document Type: Article

References (38)

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34. [8]
35. a) Not suprisingly, all attempts directed towards chemical correlation of tBu-substituted cyclic silanes 8 and 10 by oxidative degradation have failed so far. Although the ROESY NMR experiments were not completely conclusive, we assigned the relative configurations of 10 and 8 (see Supporting Information for details). Based on these measurements, we suggest the relative configurations as depicted;
36. b) HPLC analysis using two coupled Daicel Chiralcel OD-H columns (n-heptane at 0°C) for 7 provided baseline separation of enantiomers (see also Table 1).
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