Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

Oncotarget

Volumn 7, Issue 10, 2016, Pages 11094-11112

  Kim, Sinae ^a   Song, Jin Hoi ^b   Kim, Seokho ^b   Qu, Peng ^d   Martin, Betty K ^d   Sehareen, Waheed S ^d   Haines, Diana C ^c   Lin, Pengnian C ^d   Sharan, Shyam K ^d   Chang, Suhwan ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Breast cancer; C EBP beta; Cytokine; MDSC; miR 155

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; MICRORNA 155; MICRORNA; MIRN155 MICRORNA, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST CARCINOGENESIS; CANCER SURVIVAL; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; DISEASE ASSOCIATION; EFFECTOR CELL; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE LOSS; GENETIC ASSOCIATION; IN VIVO STUDY; MICROARRAY ANALYSIS; MOLECULAR DYNAMICS; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUPPRESSOR CELL; SURVIVAL RATE; SURVIVAL TIME; TUMOR FREE SURVIVAL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; GENE SILENCING; IMMUNOLOGY; METABOLISM; MUTANT MOUSE STRAIN; MYELOID-DERIVED SUPPRESSOR CELL; ONCOGENE; PATHOLOGY;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; FEMALE; GENE KNOCKDOWN TECHNIQUES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, MUTANT STRAINS; MICRORNAS; MYELOID-DERIVED SUPPRESSOR CELLS; ONCOGENES; TUMOR MICROENVIRONMENT;

EID: 84962026496     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7150     Document Type: Article

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