Role of miR-155 in the regulation of lymphocyte immune function and disease

Immunology

Volumn 142, Issue 1, 2014, Pages 32-38

  Seddiki, Nabila ^a,b   Brezar, Vedran ^a,b   Ruffin, Nicolas ^a,b   Lévy, Yves ^a,b,c   Swaminathan, Sanjay ^d,e  

^a INSERM U955   (France)

^b UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^c HENRI MONDOR HOSPITAL   (France)

^d BLACKTOWN HOSPITAL   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Experimental autoimmune encephalomyelitis multiple sclerosis; Regulatory T cells; T cells; T helper type 1 type2 cells

Indexed keywords

CYTOKINE; MICRORNA 155;

ADAPTIVE IMMUNITY; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CYTOLOGY; HEMATOLOGIC MALIGNANCY; HUMAN; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOPATHOLOGY; IMMUNOREGULATION; INFLAMMATION; LYMPHOCYTE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; VIRUS INFECTION;

EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS/MULTIPLE SCLEROSIS; REGULATORY T CELLS; T CELLS; T HELPER TYPE 1/TYPE2 CELLS;

ADAPTIVE IMMUNITY; ANIMALS; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTE SUBSETS; MICRORNAS; NEOPLASMS; TRANSCRIPTOME; VIRUS DISEASES;

EID: 84897997599     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12227     Document Type: Article

References (61)

1. Baltimore D, Boldin MP, O'Connell RM, Rao DS, Taganov KD. MicroRNAs: new regulators of immune cell development and function. Nat Immunol 2008; 9:839-45.
2. O'Connell RM, Kahn D, Gibson WS etal. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 2010; 33:607-19.
3. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136:215-33.
4. Loeb GB, Khan AA, Canner D, Hiatt JB, Shendure J, Darnell RB, Leslie CS, Rudensky AY. Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. Mol Cell 2012; 48:760-70.
5. Rodriguez A, Vigorito E, Clare S etal. Requirement of bic/microRNA-155 for normal immune function. Science 2007; 316:608-11.
6. Vigorito E, Perks KL, Abreu-Goodger C etal. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 2007; 27:847-59.
7. Kohlhaas S, Garden OA, Scudamore C, Turner M, Okkenhaug K, Vigorito E. Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells. J Immunol 2009; 182:2578-82.
8. Lu LF, Thai TH, Calado DP etal. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity 2009; 30:80-91.
9. + T cell responses to acute viral and intracellular bacterial challenges. J Immunol 2013; 190:1210-6.
10. Tsai CY, Allie SR, Zhang W, Usherwood EJ. MicroRNA miR-155 affects antiviral effector and effector Memory CD8 T cell differentiation. J Virol 2013; 87:2348-51.
11. Thai TH, Calado DP, Casola S etal. Regulation of the germinal center response by microRNA-155. Science 2007; 316:604-8.
12. Landgraf P, Rusu M, Sheridan R etal. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007; 129:1401-14.
13. Martin MM, Lee EJ, Buckenberger JA, Schmittgen TD, Elton TS. MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. J Biol Chem 2006; 281:18277-84.
14. + hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc Natl Acad Sci U S A. 2007; 104:2750-5.
15. Masaki S, Ohtsuka R, Abe Y, Muta K, Umemura T. Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis. Biochem Biophys Res Commun 2007; 364:509-14.
16. O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J, Paquette RL, Baltimore D. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 2008; 205:585-94.
17. Grigoryev YA, Kurian SM, Hart T etal. MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes. J Immunol 2011; 187:2233-43.
18. van den Berg A, Kroesen BJ, Kooistra K etal. High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma. Genes Chromosom Cancer 2003; 37:20-8.
19. Haasch D, Chen YW, Reilly RM etal. T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene BIC. Cell Immunol 2002; 217:78-86.
20. Dorsett Y, McBride KM, Jankovic M etal. MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity 2008; 28:630-8.
21. + T cell responses by regulating interferon signaling. Nat Immunol 2013; 14:593-602.
22. Bach EA, Szabo SJ, Dighe AS, Ashkenazi A, Aguet M, Murphy KM, Schreiber RD. Ligand-induced autoregulation of IFN-γ receptor β chain expression in T helper cell subsets. Science 1995; 270:1215-8.
23. Tau GZ, von der Weid T, Lu B etal. Interferon γ signaling alters the function of T helper type 1 cells. J Exp Med 2000; 192:977-86.
24. + T cells. Eur J Immunol 2010; 40:225-31.
25. O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci U S A. 2009; 106:7113-8.
26. Huffaker TB, Hu R, Runtsch MC etal. Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep 2012; 2:1697-709.
27. Bluml S, Bonelli M, Niederreiter B etal. Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice. Arthritis Rheum 2011; 63:1281-8.
28. Hu R, Huffaker TB, Kagele DA, Runtsch MC, Bake E, Chaudhuri AA, Round JL, O'Connell RM. MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expression. J Immunol 2013; 190:5972-80.
29. Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL. Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol 2011; 187:2213-21.
30. Yao R, Ma YL, Liang W, Li HH, Ma ZJ, Yu X, Liao YH. MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS ONE 2012; 7:e46082.
31. Das LM, Torres-Castillo MD, Gill T, Levine AD. TGF-β conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA. Mucosal Immunol 2013; 6:167-76.
32. Seddiki N, Santner-Nanan B, Martinson J etal. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203:1693-700.
33. + regulatory T cells in adult life. Blood 2006; 107:2830-8.
34. Eis PS, Tam W, Sun L, Chadburn A, Li Z, Gomez MF, Lund E, Dahlberg JE. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 2005; 102:3627-32.
35. Garzon R, Croce CM. MicroRNAs in normal and malignant hematopoiesis. Curr Opin Hematol 2008; 15:352-8.
36. Kluiver J, Poppema S, de Jong D, Blokzijl T, Harms G, Jacobs S, Kroesen BJ, van den Berg A. BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J Pathol 2005; 207:243-9.
37. Metzler M, Wilda M, Busch K, Viehmann S, Borkhardt A. High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosom Cancer 2004; 39:167-9.
38. Vigorito E, Kohlhaas S, Lu D, Leyland R. miR-155: an ancient regulator of the immune system. Immunol Rev 2013; 253:146-57.
39. Costinean S, Zanesi N, Pekarsky Y, Tili E, Volinia S, Heerema N, Croce CM. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci USA 2006; 103:7024-9.
40. Babar IA, Cheng CJ, Booth CJ, Liang X, Weidhaas JB, Saltzman WM, Slack FJ. Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proc Natl Acad Sci USA 2012; 109:E1695-704.
41. Calin GA, Ferracin M, Cimmino A etal. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005; 353:1793-801.
42. Lawrie CH. MicroRNAs and lymphomagenesis: a functional review. Br J Haematol 2013; 160:571-81.
43. Czyzyk-Krzeska MF, Zhang X. MiR-155 at the heart of oncogenic pathways. Oncogene 2013; doi: 10.1038/onc.2013.26.
44. Gironella M, Seux M, Xie MJ etal. Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc Natl Acad Sci USA 2007; 104:16170-5.
45. Nikiforova MN, Tseng GC, Steward D, Diorio D, Nikiforov YE. MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. J Clin Endocrinol Metab 2008; 93:1600-8.
46. Volinia S, Calin GA, Liu CG etal. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103:2257-61.
47. + T cell responses to virus infection and cancer. Immunity 2013; 38:742-53.
48. Zonari E, Pucci F, Saini M, Mazzieri R, Politi LS, Gentner B, Naldini L. A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice. Blood 2013; 122:243-52.
49. Cubillos-Ruiz JR, Baird JR, Tesone AJ etal. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Res 2012; 72:1683-93.
50. + T lymphocyte miRNA expression after exposure to HIV-1. Blood 2012; 119:6259-67.
51. Witwer KW, Clements JE. Evidence for miRNA expression differences of HIV-1-positive, treatment-naive patients and elite suppressors: a re-analysis. Blood 2012; 119:6395-6.
52. Seddiki N, Swaminathan S, Phetsouphanh C, Kelleher AD. miR-155 is differentially expressed in Treg subsets, which may explain expression level differences of miR-155 in HIV-1 infected patients. Blood 2012; 119:6396-7.
53. Su C, Hou Z, Zhang C, Tian Z, Zhang J. Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cells. Virol J 2011; 8:354.
54. Bala S, Tilahun Y, Taha O, Alao H, Kodys K, Catalano D, Szabo G. Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection. J Transl Med 2012; 10:151.
55. Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther 2008; 10:R101.
56. Leah E. Rheumatoid arthritis: miR-155 mediates inflammation. Nat Rev Rheumatol 2011; 7:437.
57. Leng RX, Pan HF, Qin WZ, Chen GM, Ye DQ. Role of microRNA-155 in autoimmunity. Cytokine Growth Factor Rev 2011; 22:141-7.
58. Spoerl D, Duroux-Richard I, Louis-Plence P, Jorgensen C. The role of miR-155 in regulatory T cells and rheumatoid arthritis. Clin Immunol 2013; 148:56-65.
59. Paraboschi EM, Solda G, Gemmati D etal. Genetic association and altered gene expression of mir-155 in multiple sclerosis patients. Int J Mol Sci 2011; 12:8695-712.
60. Junker A, Krumbholz M, Eisele S etal. MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 2009; 132(Pt 12):3342-52.
61. Cardoso AL, Guedes JR, Pereira de Almeida L, Pedroso de Lima MC. miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology 2012;135:73-88.