Targeted allelic expression profiling in human islets identifies cis-regulatory effects for multiple variants identified by type 2 diabetes genome-wide association studies

Diabetes

Volumn 64, Issue 4, 2015, Pages 1484-1491

  Locke, Jonathan M ^a   Hysenaj, Gerald ^a   Wood, Andrew R ^a   Weedon, Michael N ^a   Harries, Lorna W ^a  

^a UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANK1 PROTEIN; ANPEP PROTEIN; ARAP1 PROTEIN; CAMK2B PROTEIN; CRK ASSOCIATED SUBSTRATE PROTEIN; DNA; GENOMIC DNA; HAPLN4 PROTEIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HMG20A PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; MESSENGER RNA; NCR3LG1 PROTEIN; NOTCH2 RECEPTOR; RNA; SLC30A8 PROTEIN; SODIUM PHOSPHATE COTRANSPORTER; THADA PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; DISEASE PREDISPOSITION; EXON; GENE EXPRESSION PROFILING; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ALLELIC IMBALANCE; GENE LOCUS; GENETICS; GENOME-WIDE ASSOCIATION STUDY; REGULATORY SEQUENCE;

ALLELES; ALLELIC IMBALANCE; DIABETES MELLITUS, TYPE 2; EXONS; GENE EXPRESSION PROFILING; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; HUMANS; REGULATORY ELEMENTS, TRANSCRIPTIONAL;

EID: 84961999748     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0957     Document Type: Article

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