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Volumn 196, Issue 5, 2016, Pages 2109-2118

Treatment of uveitis by in situ administration of ex vivo-activated polyclonal regulatory T cells

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; REACTIVE OXYGEN METABOLITE;

EID: 84961994310     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1501723     Document Type: Article
Times cited : (22)

References (58)
  • 3
    • 47249124078 scopus 로고    scopus 로고
    • Human regulatory T cells: Role in autoimmune disease and therapeutic opportunities
    • Brusko, T. M., A. L. Putnam, and J. A. Bluestone. 2008. Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunol. Rev. 223: 371-390
    • (2008) Immunol. Rev. , vol.223 , pp. 371-390
    • Brusko, T.M.1    Putnam, A.L.2    Bluestone, J.A.3
  • 9
    • 0031647622 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi, T., Y. Kuniyasu, M. Toda, N. Sakaguchi, M. Itoh, M. Iwata, J. Shimizu, and S. Sakaguchi. 1998. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10: 1969-1980
    • (1998) Int. Immunol. , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6    Shimizu, J.7    Sakaguchi, S.8
  • 10
    • 0033985780 scopus 로고    scopus 로고
    • +CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton, A. M., and E. M. Shevach. 2000. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J. Immunol. 164: 183-190
    • (2000) J. Immunol. , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 11
    • 34547150491 scopus 로고    scopus 로고
    • What does the future hold for cell-based tolerogenic therapy? Nat
    • Bluestone, J. A., A. W. Thomson, E. M. Shevach, and H. L. Weiner. 2007. What does the future hold for cell-based tolerogenic therapy? Nat. Rev. Immunol. 7: 650-654
    • (2007) Rev. Immunol. , vol.7 , pp. 650-654
    • Bluestone, J.A.1    Thomson, A.W.2    Shevach, E.M.3    Weiner, H.L.4
  • 12
    • 0028359368 scopus 로고
    • Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor
    • Kirberg, J., A. Baron, S. Jakob, A. Rolink, K. Karjalainen, and H. von Boehmer. 1994. Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor. J. Exp. Med. 180: 25-34
    • (1994) J. Exp. Med. , vol.180 , pp. 25-34
    • Kirberg, J.1    Baron, A.2    Jakob, S.3    Rolink, A.4    Karjalainen, K.5    Von Boehmer, H.6
  • 13
    • 33744933703 scopus 로고    scopus 로고
    • Regulatory T cells control uveoretinitis induced by pathogenic Th1 cells reacting to a specific retinal neoantigen
    • Terrada, C., S. Fisson, Y. De Kozak, M. Kaddouri, P. Lehoang, D. Klatzmann, B. L. Salomon, and B. Bodaghi. 2006. Regulatory T cells control uveoretinitis induced by pathogenic Th1 cells reacting to a specific retinal neoantigen. J. Immunol. 176: 7171-7179
    • (2006) J. Immunol. , vol.176 , pp. 7171-7179
    • Terrada, C.1    Fisson, S.2    De Kozak, Y.3    Kaddouri, M.4    Lehoang, P.5    Klatzmann, D.6    Salomon, B.L.7    Bodaghi, B.8
  • 14
    • 44649146027 scopus 로고    scopus 로고
    • Experimental autoimmune uveoretinitis in the rat and mouse
    • Chapter 15: Unit 15.16
    • Caspi, R. R. 2003. Experimental autoimmune uveoretinitis in the rat and mouse. Curr. Protoc. Immunol. Chapter 15: Unit 15.16
    • (2003) Curr. Protoc. Immunol
    • Caspi, R.R.1
  • 16
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
    • Tang, Q., and J. A. Bluestone. 2008. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 9: 239-244
    • (2008) Nat. Immunol. , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 17
    • 82755184094 scopus 로고    scopus 로고
    • Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or noninflammatory conditions
    • Yamaguchi, T., J. B. Wing, and S. Sakaguchi. 2011. Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or noninflammatory conditions. Semin. Immunol. 23: 424-430
    • (2011) Semin. Immunol. , vol.23 , pp. 424-430
    • Yamaguchi, T.1    Wing, J.B.2    Sakaguchi, S.3
  • 18
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • Josefowicz, S. Z., L. F. Lu, and A. Y. Rudensky. 2012. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30: 531-564
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.F.2    Rudensky, A.Y.3
  • 20
    • 42249084849 scopus 로고    scopus 로고
    • Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
    • Luger, D., P. B. Silver, J. Tang, D. Cua, Z. Chen, Y. Iwakura, E. P. Bowman, N. M. Sgambellone, C. C. Chan, and R. R. Caspi. 2008. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J. Exp. Med. 205: 799-810
    • (2008) J. Exp. Med. , vol.205 , pp. 799-810
    • Luger, D.1    Silver, P.B.2    Tang, J.3    Cua, D.4    Chen, Z.5    Iwakura, Y.6    Bowman, E.P.7    Sgambellone, N.M.8    Chan, C.C.9    Caspi, R.R.10
  • 21
    • 84869111825 scopus 로고    scopus 로고
    • Dynamics of intraocular IFN-γ, IL-17 and IL-10-producing cell populations during relapsing and monophasic rat experimental autoimmune uveitis
    • Kaufmann, U., M. Diedrichs-Möhring, and G. Wildner. 2012. Dynamics of intraocular IFN-γ, IL-17 and IL-10-producing cell populations during relapsing and monophasic rat experimental autoimmune uveitis. PLoS One 7: e49008
    • (2012) PLoS One , vol.7 , pp. e49008
    • Kaufmann, U.1    Diedrichs-Möhring, M.2    Wildner, G.3
  • 23
    • 79961008060 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis
    • Haruta, H., N. Ohguro, M. Fujimoto, S. Hohki, F. Terabe, S. Serada, S. Nomura, K. Nishida, T. Kishimoto, and T. Naka. 2011. Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis. Invest. Ophthalmol. Vis. Sci. 52: 3264-3271
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 3264-3271
    • Haruta, H.1    Ohguro, N.2    Fujimoto, M.3    Hohki, S.4    Terabe, F.5    Serada, S.6    Nomura, S.7    Nishida, K.8    Kishimoto, T.9    Naka, T.10
  • 24
    • 0029821210 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming
    • Sartani, G., P. B. Silver, L. V. Rizzo, C. C. Chan, B. Wiggert, G. Mastorakos, and R. R. Caspi. 1996. Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming. Invest. Ophthalmol. Vis. Sci. 37: 2211-2218
    • (1996) Invest. Ophthalmol. Vis. Sci. , vol.37 , pp. 2211-2218
    • Sartani, G.1    Silver, P.B.2    Rizzo, L.V.3    Chan, C.C.4    Wiggert, B.5    Mastorakos, G.6    Caspi, R.R.7
  • 25
    • 84879518149 scopus 로고    scopus 로고
    • Systematic review of antitumor necrosis factor-a therapy for treatment of immune-mediated uveitis
    • Cordero-Coma, M., T. Yilmaz, and S. Onal. 2013. Systematic review of antitumor necrosis factor-a therapy for treatment of immune-mediated uveitis. Ocul. Immunol. Inflamm. 21: 19-27
    • (2013) Ocul. Immunol. Inflamm. , vol.21 , pp. 19-27
    • Cordero-Coma, M.1    Yilmaz, T.2    Onal, S.3
  • 30
    • 33845630668 scopus 로고    scopus 로고
    • Anti-inflammatory effect of interleukin-10 on human neutrophil respiratory burst involves inhibition of GM-CSF-induced p47PHOX phosphorylation through a decrease in ERK1/2 activity
    • Dang, P. M., C. Elbim, J. C. Marie, M. Chiandotto, M. A. Gougerot-Pocidalo, and J. El-Benna. 2006. Anti-inflammatory effect of interleukin-10 on human neutrophil respiratory burst involves inhibition of GM-CSF-induced p47PHOX phosphorylation through a decrease in ERK1/2 activity. FASEB J. 20: 1504-1506
    • (2006) FASEB J. , vol.20 , pp. 1504-1506
    • Dang, P.M.1    Elbim, C.2    Marie, J.C.3    Chiandotto, M.4    Gougerot-Pocidalo, M.A.5    El-Benna, J.6
  • 31
    • 84902588276 scopus 로고    scopus 로고
    • IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis
    • Li, B., R. Alli, P. Vogel, and T. L. Geiger. 2014. IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis. Mucosal Immunol. 7: 869-878
    • (2014) Mucosal Immunol. , vol.7 , pp. 869-878
    • Li, B.1    Alli, R.2    Vogel, P.3    Geiger, T.L.4
  • 32
    • 84876931396 scopus 로고    scopus 로고
    • Beyond oxidative stress: An immunologist's guide to reactive oxygen species
    • Nathan, C., and A. Cunningham-Bussel. 2013. Beyond oxidative stress: an immunologist's guide to reactive oxygen species. Nat. Rev. Immunol. 13: 349-361
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 349-361
    • Nathan, C.1    Cunningham-Bussel, A.2
  • 33
    • 0033579875 scopus 로고    scopus 로고
    • Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
    • Höglund, P., J. Mintern, C. Waltzinger, W. Heath, C. Benoist, and D. Mathis. 1999. Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes. J. Exp. Med. 189: 331-339
    • (1999) J. Exp. Med. , vol.189 , pp. 331-339
    • Höglund, P.1    Mintern, J.2    Waltzinger, C.3    Heath, W.4    Benoist, C.5    Mathis, D.6
  • 34
    • 0037025990 scopus 로고    scopus 로고
    • Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice
    • Gagnerault, M. C., J. J. Luan, C. Lotton, and F. Lepault. 2002. Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice. J. Exp. Med. 196: 369-377
    • (2002) J. Exp. Med. , vol.196 , pp. 369-377
    • Gagnerault, M.C.1    Luan, J.J.2    Lotton, C.3    Lepault, F.4
  • 35
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • McMahon, E. J., S. L. Bailey, C. V. Castenada, H. Waldner, and S. D. Miller. 2005. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat. Med. 11: 335-339
    • (2005) Nat. Med. , vol.11 , pp. 335-339
    • McMahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3    Waldner, H.4    Miller, S.D.5
  • 36
    • 33846472053 scopus 로고    scopus 로고
    • + T (H)-17 cells in relapsing EAE
    • Bailey, S. L., B. Schreiner, E. J. McMahon, and S. D. Miller. 2007. CNS myeloid DCs presenting endogenous myelin peptides "preferentially" polarize CD4+ T (H)-17 cells in relapsing EAE. Nat. Immunol. 8: 172-180
    • (2007) Nat. Immunol. , vol.8 , pp. 172-180
    • Bailey, S.L.1    Schreiner, B.2    McMahon, E.J.3    Miller, S.D.4
  • 38
    • 65449122461 scopus 로고    scopus 로고
    • Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg
    • Stephens, L. A., K. H. Malpass, and S. M. Anderton. 2009. Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg. Eur. J. Immunol. 39: 1108-1117
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1108-1117
    • Stephens, L.A.1    Malpass, K.H.2    Anderton, S.M.3
  • 39
    • 0036851922 scopus 로고    scopus 로고
    • Induction of regulatory T cells by the immunomodulating cytokines a-melanocyte-stimulating hormone and transforming growth factor-b2
    • Namba, K., N. Kitaichi, T. Nishida, and A. W. Taylor. 2002. Induction of regulatory T cells by the immunomodulating cytokines a-melanocyte-stimulating hormone and transforming growth factor-b2. J. Leukoc. Biol. 72: 946-952
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 946-952
    • Namba, K.1    Kitaichi, N.2    Nishida, T.3    Taylor, A.W.4
  • 40
    • 33645863161 scopus 로고    scopus 로고
    • +CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity
    • Grajewski, R. S., P. B. Silver, R. K. Agarwal, S. B. Su, C. C. Chan, G. I. Liou, and R. R. Caspi. 2006. Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity. J. Exp. Med. 203: 851-856
    • (2006) J. Exp. Med. , vol.203 , pp. 851-856
    • Grajewski, R.S.1    Silver, P.B.2    Agarwal, R.K.3    Su, S.B.4    Chan, C.C.5    Liou, G.I.6    Caspi, R.R.7
  • 41
    • 33847122930 scopus 로고    scopus 로고
    • +CD25+ T regulatory cells induced by LPS-activated bone marrow dendritic cells suppress experimental autoimmune uveoretinitis in vivo
    • Siepmann, K., S. Biester, J. Plsková, E. Muckersie, L. Duncan, and J. V. Forrester. 2007. CD4+CD25+ T regulatory cells induced by LPS-activated bone marrow dendritic cells suppress experimental autoimmune uveoretinitis in vivo. Graefes Arch. Clin. Exp. Ophthalmol. 245: 221-229
    • (2007) Graefes Arch. Clin. Exp. Ophthalmol. , vol.245 , pp. 221-229
    • Siepmann, K.1    Biester, S.2    Plsková, J.3    Muckersie, E.4    Duncan, L.5    Forrester, J.V.6
  • 42
    • 75749096344 scopus 로고    scopus 로고
    • +CD25+ T cells to the regression phase of experimental autoimmune uveoretinitis
    • Sun, M., P. Yang, L. Du, H. Zhou, X. Ren, and A. Kijlstra. 2010. Contribution of CD4+CD25+ T cells to the regression phase of experimental autoimmune uveoretinitis. Invest. Ophthalmol. Vis. Sci. 51: 383-389
    • Invest Ophthalmol. Vis. Sci. , vol.51 , pp. 383-389
    • Sun, M.1    Yang, P.2    Du, L.3    Zhou, H.4    Ren, X.5    Kijlstra, A.6
  • 43
    • 65449125930 scopus 로고    scopus 로고
    • Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
    • Duarte, J. H., S. Zelenay, M. L. Bergman, A. C. Martins, and J. Demengeot. 2009. Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. Eur. J. Immunol. 39: 948-955
    • (2009) Eur. J. Immunol. , vol.39 , pp. 948-955
    • Duarte, J.H.1    Zelenay, S.2    Bergman, M.L.3    Martins, A.C.4    Demengeot, J.5
  • 46
    • 70249094359 scopus 로고    scopus 로고
    • Peripheral induction of tolerance by retinal antigen expression
    • Gregerson, D. S., N. D. Heuss, U. Lehmann, and S. W. McPherson. 2009. Peripheral induction of tolerance by retinal antigen expression. J. Immunol. 183: 814-822
    • (2009) J. Immunol. , vol.183 , pp. 814-822
    • Gregerson, D.S.1    Heuss, N.D.2    Lehmann, U.3    McPherson, S.W.4
  • 48
    • 56549105942 scopus 로고    scopus 로고
    • Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations
    • Kerr, E. C., B. J. Raveney, D. A. Copland, A. D. Dick, and L. B. Nicholson. 2008. Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. J. Autoimmun. 31: 354-361
    • (2008) J. Autoimmun. , vol.31 , pp. 354-361
    • Kerr, E.C.1    Raveney, B.J.2    Copland, D.A.3    Dick, A.D.4    Nicholson, L.B.5
  • 49
    • 49049113716 scopus 로고    scopus 로고
    • +CD25high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome
    • Chen, L., P. Yang, H. Zhou, H. He, X. Ren, W. Chi, L. Wang, and A. Kijlstra. 2008. Diminished frequency and function of CD4+CD25high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome. Invest. Ophthalmol. Vis. Sci. 49: 3475-3482
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3475-3482
    • Chen, L.1    Yang, P.2    Zhou, H.3    He, H.4    Ren, X.5    Chi, W.6    Wang, L.7    Kijlstra, A.8
  • 58
    • 84914670823 scopus 로고    scopus 로고
    • Review of systemic immunosuppression for autoimmune uveitis
    • Castiblanco, C., and C. S. Foster. 2014. Review of systemic immunosuppression for autoimmune uveitis. Ophthalmol. Ther. 3: 17-36
    • (2014) Ophthalmol. Ther. , vol.3 , pp. 17-36
    • Castiblanco, C.1    Foster, C.S.2


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