Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells

Epigenetics

Volumn 10, Issue 11, 2015, Pages 1006-1013

  Jin, Chunlei ^a,b   Qin, Taichun ^b   Barton, Michelle Craig ^b   Jelinek, Jaroslav ^a   Issa, Jean Pierre J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Base excision repair; DNA damage; DNA demethylation pathway; DNA replication; TET genes

Indexed keywords

BISULFITE; CHECKPOINT KINASE 2; COMPLEMENTARY DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DOXYCYCLINE; HISTONE H2AX; LENTIVIRUS VECTOR; PROTEIN P53; REDOX EFFECTOR FACTOR 1; SMALL INTERFERING RNA; THYMINE DNA GLYCOSYLASE; XRCC1 PROTEIN; APEX1 PROTEIN, HUMAN; MIXED FUNCTION OXIDASE; ONCOPROTEIN; TET1 PROTEIN, HUMAN;

ARTICLE; CELL CYCLE ARREST; CELL GROWTH; CONTROLLED STUDY; DNA DAMAGE; DNA DEMETHYLATION; DNA METHYLATION; DNA REPLICATION; DOT HYBRIDIZATION; EXCISION REPAIR; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; OPEN READING FRAME; PROTEIN PHOSPHORYLATION; PYROSEQUENCING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEN ELEVEN TRANSLOCATION GENE; UPREGULATION; WESTERN BLOTTING; CELL PROLIFERATION; DEFICIENCY; DNA REPAIR; METABOLISM;

CELL PROLIFERATION; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HEK293 CELLS; HUMANS; MIXED FUNCTION OXYGENASES; PROTO-ONCOGENE PROTEINS; THYMINE DNA GLYCOSYLASE;

EID: 84961992325     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1091145     Document Type: Article

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