Loss of B cells in patients with heterozygous mutations in IKAROS

New England Journal of Medicine

Volumn 374, Issue 11, 2016, Pages 1032-1043

  Kuehn, Hye Sun ^a   Boisson, Bertrand ^c   Cunningham Rundles, Charlotte ^e   Reichenbach, Janine ^g,h,i   Stray Pedersen, Asbjørg ^j,k   Gelfand, Erwin W ^m   Maffucci, Patrick ^e   Pierce, Keith R ^l   Abbott, Jordan K ^m   Voelkerding, Karl V ⁿ   South, Sarah T ⁿ   Augustine, Nancy H ⁿ   Bush, Jeana S ^p   Dolen, William K ^p   Wray, Betty B ^p   Itan, Yuval ^c   Cobat, Aurelie ^c,f   Sorte, Hanne Sørmo ^k   Ganesan, Sundar ^b   Prader, Seraina ^g,h   Martins, Thomas B ^n,o   Lawrence, Monica G ^q   Orange, Jordan S ^j   Calvo, Katherine R ^a   Niemela, Julie E ^a   Casanova, Jean Laurent ^c,d,f   Fleisher, Thomas A ^a   Hill, Harry R ⁿ   Kumánovics, Attila ⁿ   Conley, Mary Ellen ^c   Rosenzweig, Sergio D ^a,b   more..

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f IMAGINE INSTITUTE   (France)

^g UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^h Children's Research Center   (Switzerland)

ⁱ UNIVERSITY OF ZURICH   (Switzerland)

^j BAYLOR COLLEGE OF MEDICINE   (United States)

^k OSLO UNIVERSITY HOSPITAL   (Norway)

^l UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^m DEPARTMENT OF MEDICINE   (United States)

ⁿ UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^o ARUP INSTITUTE FOR CLINICAL AND EXPERIMENTAL PATHOLOGY   (United States)

^p MEDICAL COLLEGE OF GEORGIA   (United States)

^q UNIVERSITY OF VIRGINIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A13; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; IKAROS TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; IKZF1 PROTEIN, HUMAN; IMMUNOGLOBULIN G; LEUKOCYTE ANTIGEN;

ABCA13 GENE; ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; B LYMPHOCYTE; C7ORF7 GENE; CDC14C GENE; CELL LOSS; CHILD; CLINICAL ARTICLE; COBL GENE; COMMON VARIABLE IMMUNODEFICIENCY; COMPARATIVE GENOMIC HYBRIDIZATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CTLA4 GENE; DDC GENE; DNA BINDING; DNA SEQUENCE; EXOME; FEMALE; FIGNL1 GENE; FLOW CYTOMETRY; GATA2 GENE; GEL MOBILITY SHIFT ASSAY; GENE; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; GRB10 GENE; HETEROZYGOSITY; HUMAN; IKZF1 GENE; INFANT; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MISSENSE MUTATION; MUTATIONAL ANALYSIS; POM121L12 GENE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEQUENCE ANALYSIS; TNFRS13B GENE; TRANSCRIPTION REGULATION; VWC2 GENE; YOUNG ADULT; ZPBP GENE; BLOOD; BONE MARROW; BONE MARROW EXAMINATION; CHROMOSOME 7; GENETICS; HETEROZYGOTE; IMMUNOLOGY; MUTATION; PEDIGREE; PROCEDURES;

ADOLESCENT; ADULT; ANTIGENS, CD; B-LYMPHOCYTES; BONE MARROW; BONE MARROW EXAMINATION; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 7; COMMON VARIABLE IMMUNODEFICIENCY; EXOME; FEMALE; HETEROZYGOTE; HUMANS; IKAROS TRANSCRIPTION FACTOR; IMMUNOGLOBULIN G; LYMPHOCYTE COUNT; MALE; MUTATION; PEDIGREE; SEQUENCE ANALYSIS, DNA;

EID: 84961859429     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1512234     Document Type: Article

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