Curcumin Rescues a PINK1 Knock Down SH-SY5Y Cellular Model of Parkinson’s Disease from Mitochondrial Dysfunction and Cell Death

Molecular Neurobiology

Volumn 54, Issue 4, 2017, Pages 2752-2762

  van der Merwe, Celia ^a   van Dyk, Hayley Christy ^b   Engelbrecht, Lize ^c   van der Westhuizen, Francois Hendrikus ^b   Kinnear, Craig ^a,c   Loos, Ben ^c   Bardien, Soraya ^a  

^a UNIVERSITY OF STELLENBOSCH   (South Africa)

^b NORTH WEST UNIVERSITY   (South Africa)

^c STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Apoptosis; Curcumin; Mitochondrial dysfunction; Parkinson s disease; PINK1

Indexed keywords

ADENOSINE TRIPHOSPHATE; CURCUMIN; PARAQUAT; SMALL INTERFERING RNA; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME SYNTHESIS; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; LIMIT OF QUANTITATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PINK1 GENE; BIOLOGICAL MODEL; CELL DEATH; CELL FUSION; CELL RESPIRATION; CELL SURVIVAL; DRUG EFFECTS; ELECTRON TRANSPORT; ENZYMOLOGY; GENE SILENCING; HUMAN; METABOLISM; OXYGEN CONSUMPTION; PATHOLOGY; TUMOR CELL LINE;

CELL DEATH; CELL FUSION; CELL LINE, TUMOR; CELL RESPIRATION; CELL SURVIVAL; CURCUMIN; ELECTRON TRANSPORT; GENE KNOCKDOWN TECHNIQUES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; OXYGEN CONSUMPTION; PARAQUAT; PARKINSON DISEASE; PROTEIN KINASES; RNA, SMALL INTERFERING;

EID: 84961842084     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9843-0     Document Type: Article

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