Glutamoyl diester of the dietary polyphenol curcumin offers improved protection against peroxynitrite-mediated nitrosative stress and damage of brain mitochondria in vitro: Implications for Parkinson's disease

Molecular and Cellular Biochemistry

Volumn 347, Issue 1-2, 2011, Pages 135-143

  Mythri, Rajeswara Babu ^a   Harish, G ^a   Dubey, Shiv Kumar ^b,d   Misra, Krishna ^c   Srinivas Bharath, M M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b UNIVERSITY OF ALLAHABAD   (India)

^c INDIAN INSTITUTE OF INFORMATION TECHNOLOGY   (India)

^d UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

Bioconjugates; Curcumin; Mitochondria; Neurodegeneration; Nitrosative stress; Protein nitration

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CURCUMIN; PEROXYNITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMICAL COMPOSITION; BRAIN MITOCHONDRION; CELL DEATH; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NITRATION; NITROSATIVE STRESS; NONHUMAN; PARKINSON DISEASE; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; BRAIN; CURCUMIN; DIET; ELECTRON TRANSPORT COMPLEX I; ESTERS; FLAVONOIDS; GLUTAMATES; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOCHONDRIAL SWELLING; PARKINSON DISEASE; PEROXYNITROUS ACID; PHENOLS; PROTECTIVE AGENTS; TYROSINE;

EID: 78651280379     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0621-4     Document Type: Article

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