메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Abrupt suspension of probiotics administration may increase host pathogen susceptibility by inducing gut dysbiosis

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BILE ACID; PROBIOTIC AGENT;

EID: 84961778408     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23214     Document Type: Article
Times cited : (58)

References (60)
  • 1
    • 79955935457 scopus 로고    scopus 로고
    • Intestinal microbiota in inflammatory bowel disease friend of foe
    • Fava, F., Danese, S. Intestinal microbiota in inflammatory bowel disease: friend of foe World J Gastroenterol 17, 557 (2011).
    • (2011) World J Gastroenterol , vol.17 , pp. 557
    • Fava, F.1    Danese, S.2
  • 2
    • 38049186826 scopus 로고    scopus 로고
    • Insulin signaling and the heat shock response modulate protein homeostasis in the Caenorhabditis elegans intestine during infection
    • Mohri-Shiomi, A., Garsin, D. A. Insulin signaling and the heat shock response modulate protein homeostasis in the Caenorhabditis elegans intestine during infection. J Biol Chem 283, 194-201 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 194-201
    • Mohri-Shiomi, A.1    Garsin, D.A.2
  • 3
    • 0035843993 scopus 로고    scopus 로고
    • Commensal host-bacterial relationships in the gut
    • Hooper, L. V., Gordon, J. I. Commensal host-bacterial relationships in the gut. Science 292, 1115-1118 (2001).
    • (2001) Science , vol.292 , pp. 1115-1118
    • Hooper, L.V.1    Gordon, J.I.2
  • 4
    • 69949088176 scopus 로고    scopus 로고
    • Better living through microbial action: The benefits of the mammalian gastrointestinal microbiota on the host
    • Leser, T. D., Molbak, L. Better living through microbial action: the benefits of the mammalian gastrointestinal microbiota on the host. Environ Microbiol 11, 2194-2206 (2009).
    • (2009) Environ Microbiol , vol.11 , pp. 2194-2206
    • Leser, T.D.1    Molbak, L.2
  • 5
    • 77950353786 scopus 로고    scopus 로고
    • Homeostasis and inflammation in the intestine
    • Garrett, W. S., Gordon, J. I., Glimcher, L. H. Homeostasis and inflammation in the intestine. Cell 140, 859-870 (2010).
    • (2010) Cell , vol.140 , pp. 859-870
    • Garrett, W.S.1    Gordon, J.I.2    Glimcher, L.H.3
  • 6
    • 77955655862 scopus 로고    scopus 로고
    • Microbiota-stimulated immune mechanisms to maintain gut homeostasis
    • Chung, H., Kasper, D. L. Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Curr Opin Immunol 22, 455-460 (2010).
    • (2010) Curr Opin Immunol , vol.22 , pp. 455-460
    • Chung, H.1    Kasper, D.L.2
  • 8
    • 84870016400 scopus 로고    scopus 로고
    • Host-microbial interactions and regulation of intestinal epithelial barrier function: From physiology to pathology
    • Yu, L. C. H., Wang, J. T., Wei, S. C., Ni, Y. H. Host-microbial interactions and regulation of intestinal epithelial barrier function: From physiology to pathology. World J Gastrointest Pathophysiol 3, 27 (2012).
    • (2012) World J Gastrointest Pathophysiol , vol.3 , pp. 27
    • Yu, L.C.H.1    Wang, J.T.2    Wei, S.C.3    Ni, Y.H.4
  • 9
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A., Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nat Immuno 5, 987-995 (2004).
    • (2004) Nat Immuno , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 10
    • 84912143763 scopus 로고    scopus 로고
    • Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity
    • Estaki, M., DeCoffe, D., Gibson, D. L. Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity. World J Gastroenterol 20, 15650-15656 (2014).
    • (2014) World J Gastroenterol , vol.20 , pp. 15650-15656
    • Estaki, M.1    DeCoffe, D.2    Gibson, D.L.3
  • 11
    • 84956681881 scopus 로고    scopus 로고
    • Heat shock proteins: Intestinal gatekeepers that are influenced by dietary components and the gut microbiota
    • Liu, H., Dicksved, J., Lundh, T., Lindberg, J. E. Heat shock proteins: intestinal gatekeepers that are influenced by dietary components and the gut microbiota. Pathogens 3, 187-210 (2014).
    • (2014) Pathogens , vol.3 , pp. 187-210
    • Liu, H.1    Dicksved, J.2    Lundh, T.3    Lindberg, J.E.4
  • 12
    • 79955018521 scopus 로고    scopus 로고
    • Amino acid metabolism in intestinal bacteria: Links between gut ecology and host health
    • Dai, Z. L., Wu, G., Zhu, W. Y. Amino acid metabolism in intestinal bacteria: links between gut ecology and host health. Front Biosci (Landmark Ed), 1768-1786 (2011).
    • (2011) Front Biosci (Landmark Ed , pp. 1768-1786
    • Dai, Z.L.1    Wu, G.2    Zhu, W.Y.3
  • 13
    • 84903720102 scopus 로고    scopus 로고
    • Metabolic effects of bile acids in the gut in health and disease
    • Boesjes, M., Brufau, G. Metabolic effects of bile acids in the gut in health and disease. Curr Med Chem 21, 2822-2829 (2014).
    • (2014) Curr Med Chem , vol.21 , pp. 2822-2829
    • Boesjes, M.1    Brufau, G.2
  • 14
    • 80555143077 scopus 로고    scopus 로고
    • Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling
    • Shin, S. C. et al. Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. Science 334, 670-674 (2011).
    • (2011) Science , vol.334 , pp. 670-674
    • Shin, S.C.1
  • 15
    • 84929717524 scopus 로고    scopus 로고
    • Amino acid metabolism in intestinal bacteria and its potential implications for mammalian reproduction
    • Dai, Z., Wu, Z., Hang, S., Zhu, W., Wu, G. Amino acid metabolism in intestinal bacteria and its potential implications for mammalian reproduction. Mol Hum Reprod 21, 389-409 (2015).
    • (2015) Mol Hum Reprod , vol.21 , pp. 389-409
    • Dai, Z.1    Wu, Z.2    Hang, S.3    Zhu, W.4    Wu, G.5
  • 17
    • 84947552418 scopus 로고    scopus 로고
    • Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks
    • gutjnl-2014-308820
    • Morgun, A. et al. Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks. Gut, gutjnl-2014-308820 (2015).
    • (2015) Gut
    • Morgun, A.1
  • 18
    • 84949313802 scopus 로고    scopus 로고
    • Scientific evidence for health effects attributed to the consumption of probiotics and prebiotics: An update for current perspectives and future challenges
    • Martinez, R. C. R., Bedani, R., Saad, S. M. I. Scientific evidence for health effects attributed to the consumption of probiotics and prebiotics: an update for current perspectives and future challenges. Brit J Nutr 114, 1993-2015 (2015).
    • (2015) Brit J Nutr , vol.114 , pp. 1993-2015
    • Martinez, R.C.R.1    Bedani, R.2    Saad, S.M.I.3
  • 19
    • 0032421155 scopus 로고    scopus 로고
    • Lactobacillus species as opportunistic pathogens in immunocompromised patients
    • Schlegel, L., Lemerle, S., Geslin, P. Lactobacillus species as opportunistic pathogens in immunocompromised patients. Eur J Clin Microbiol 17, 887-888 (1998).
    • (1998) Eur J Clin Microbiol , vol.17 , pp. 887-888
    • Schlegel, L.1    Lemerle, S.2    Geslin, P.3
  • 20
    • 0033061526 scopus 로고    scopus 로고
    • Safety of industrial lactic acid bacteria
    • Adams, M. Safety of industrial lactic acid bacteria. J Biotechnol 68, 171-178 (1999).
    • (1999) J Biotechnol , vol.68 , pp. 171-178
    • Adams, M.1
  • 21
    • 0037443844 scopus 로고    scopus 로고
    • Safety of probiotics that contain lactobacilli or bifidobacteria
    • Borriello, S. et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 36, 775-780 (2003).
    • (2003) Clin Infect Dis , vol.36 , pp. 775-780
    • Borriello, S.1
  • 22
    • 33646229795 scopus 로고    scopus 로고
    • The role of probiotics in the management of allergic disease
    • Boyle, R., Tang, M. The role of probiotics in the management of allergic disease. Clini Exp Allergy 36, 568-576 (2006).
    • (2006) Clini Exp Allergy , vol.36 , pp. 568-576
    • Boyle, R.1    Tang, M.2
  • 23
    • 84904069723 scopus 로고    scopus 로고
    • Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice
    • Ji, Y. et al. Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. Cell Rep 8, 137-149 (2014).
    • (2014) Cell Rep , vol.8 , pp. 137-149
    • Ji, Y.1
  • 25
    • 0242364218 scopus 로고    scopus 로고
    • Fish immune system. A crossroads between innate and adaptive responses
    • Tort, L., Balasch, J., Mackenzie, S. Fish immune system. A crossroads between innate and adaptive responses. Inmunolog 22, 277-286 (2003).
    • (2003) Inmunolog , vol.22 , pp. 277-286
    • Tort, L.1    Balasch, J.2    MacKenzie, S.3
  • 26
    • 84878494915 scopus 로고    scopus 로고
    • Lactobacillus planarum subsp. Plantarum JCM 1149 vs. Aeromonas hydrophila NJ-1 in the anterior intestine and posterior intestine of hybrid tilapia Oreochromis niloticus Oreochromis aureus : An ex vivo study
    • Ren, P. et al. Lactobacillus planarum subsp. plantarum JCM 1149 vs. Aeromonas hydrophila NJ-1 in the anterior intestine and posterior intestine of hybrid tilapia Oreochromis niloticus Oreochromis aureus : An ex vivo study. Fish Shellfish Immunol 35, 146-153 (2013).
    • (2013) Fish Shellfish Immunol , vol.35 , pp. 146-153
    • Ren, P.1
  • 27
    • 84878485703 scopus 로고    scopus 로고
    • Comparison of adhesive gut bacteria composition, immunity, and disease resistance in juvenile hybrid tilapia fed two different Lactobacillus strains
    • Liu, W. et al. Comparison of adhesive gut bacteria composition, immunity, and disease resistance in juvenile hybrid tilapia fed two different Lactobacillus strains. Fish Shellfish Immunol 35, 54-62 (2013).
    • (2013) Fish Shellfish Immunol , vol.35 , pp. 54-62
    • Liu, W.1
  • 28
    • 36749024487 scopus 로고    scopus 로고
    • Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
    • Bates, J. M., Akerlund, J., Mittge, E., Guillemin, K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe 2, 371-382 (2007).
    • (2007) Cell Host Microbe , vol.2 , pp. 371-382
    • Bates, J.M.1    Akerlund, J.2    Mittge, E.3    Guillemin, K.4
  • 29
    • 84883285752 scopus 로고    scopus 로고
    • The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport 1
    • Lomasney, K. W., Hyland, N. P. The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport 1. Can J Physiol Pharmacol 91, 663-670 (2013).
    • (2013) Can J Physiol Pharmacol , vol.91 , pp. 663-670
    • Lomasney, K.W.1    Hyland, N.P.2
  • 30
    • 79953170241 scopus 로고    scopus 로고
    • Effect of antibiotic treatment on the intestinal metabolome
    • Antunes, L. C. M. et al. Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother 55, 1494-1503 (2011).
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1494-1503
    • Antunes, L.C.M.1
  • 31
    • 84925522956 scopus 로고    scopus 로고
    • The main Aeromonas pathogenic factors
    • Tomas, J. The main Aeromonas pathogenic factors. ISRN Microbiology 2012 (2012).
    • (2012) ISRN Microbiology 2012
    • Tomas, J.1
  • 32
    • 84930580146 scopus 로고    scopus 로고
    • Gut Microbiota cirrhosis, and alcohol regulate bile acid metabolism in the gut
    • Ridlon, J. M., Kang, D. J., Hylemon, P. B., Bajaj, J. S. Gut Microbiota, cirrhosis, and alcohol regulate bile acid metabolism in the gut. Dig Dis 33, 338-345 (2015).
    • (2015) Dig Dis , vol.33 , pp. 338-345
    • Ridlon, J.M.1    Kang, D.J.2    Hylemon, P.B.3    Bajaj, J.S.4
  • 33
    • 84983110883 scopus 로고    scopus 로고
    • Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4
    • Out, C. et al. Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4. J Hepatol (2015).
    • (2015) J Hepatol
    • Out, C.1
  • 34
    • 51649086648 scopus 로고    scopus 로고
    • Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome
    • Jones, B. V., Begley, M., Hill, C., Gahan, C. G., Marchesi, J. R. Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc Natl Acad Sci USA 105, 13580-13585 (2008).
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13580-13585
    • Jones, B.V.1    Begley, M.2    Hill, C.3    Gahan, C.G.4    Marchesi, J.R.5
  • 35
    • 84896118845 scopus 로고    scopus 로고
    • The human microbiome and bile acid metabolism: Dysbiosis, dysmetabolism, disease and intervention
    • Jones, M. L., Martoni, C. J., Ganopolsky, J. G., Labbe, A., Prakash, S. The human microbiome and bile acid metabolism: dysbiosis, dysmetabolism, disease and intervention. Expert Opin Biol Ther 14, 467-482 (2014).
    • (2014) Expert Opin Biol Ther , vol.14 , pp. 467-482
    • Jones, M.L.1    Martoni, C.J.2    Ganopolsky, J.G.3    Labbe, A.4    Prakash, S.5
  • 36
    • 84873342775 scopus 로고    scopus 로고
    • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
    • Sayin, S. I. et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab 17, 225-235 (2013).
    • (2013) Cell Metab , vol.17 , pp. 225-235
    • Sayin, S.I.1
  • 37
    • 65249154282 scopus 로고    scopus 로고
    • Panorganismal gut microbiome host metabolic crosstalk
    • Martin, F. P. J. et al. Panorganismal gut microbiome host metabolic crosstalk. J Proteome Res 8, 2090-2105 (2009).
    • (2009) J Proteome Res , vol.8 , pp. 2090-2105
    • Martin, F.P.J.1
  • 38
    • 34248206714 scopus 로고    scopus 로고
    • Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magicangle-spinning NMR spectroscopy
    • Martin, F. P. J. et al. Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magicangle-spinning NMR spectroscopy. J Proteome Res 6, 1471-1481 (2007).
    • (2007) J Proteome Res , vol.6 , pp. 1471-1481
    • Martin, F.P.J.1
  • 39
    • 38349078772 scopus 로고    scopus 로고
    • Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model
    • Martin, F. P. J. et al. Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model. Mol Syst Biol 4, 157 (2008).
    • (2008) Mol Syst Biol , vol.4 , pp. 157
    • Martin, F.P.J.1
  • 41
    • 77249104532 scopus 로고    scopus 로고
    • Inhibitory role for GABA in autoimmune inflammation
    • Bhat, R. et al. Inhibitory role for GABA in autoimmune inflammation. Proc Natl Acad Sci USA 107, 2580-2585 (2010).
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2580-2585
    • Bhat, R.1
  • 42
    • 84945455872 scopus 로고    scopus 로고
    • Antibiotic-induced imbalances in gut microbiota aggravates cholesterol accumulation and liver injuries in rats fed a high-cholesterol diet
    • Hu, X. et al. Antibiotic-induced imbalances in gut microbiota aggravates cholesterol accumulation and liver injuries in rats fed a high-cholesterol diet. Appl Microbiol Biotechnol 99, 9111-9122 (2015).
    • (2015) Appl Microbiol Biotechnol , vol.99 , pp. 9111-9122
    • Hu, X.1
  • 43
    • 34248152283 scopus 로고    scopus 로고
    • Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
    • Jernberg, C., Lofmark, S., Edlund, C., Jansson, J. K. Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. The ISME journal 1, 56-66 (2007).
    • (2007) The ISME Journal , vol.1 , pp. 56-66
    • Jernberg, C.1    Lofmark, S.2    Edlund, C.3    Jansson, J.K.4
  • 44
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen, L., Huse, S., Sogin, M. L., Relman, D. A. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol 6, e280 (2008).
    • (2008) PLoS Biol , vol.6 , pp. e280
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4
  • 45
    • 0036300743 scopus 로고    scopus 로고
    • Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces
    • Zoetendal, E. G. et al. Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol 68, 3401-3407 (2002).
    • (2002) Appl Environ Microbiol , vol.68 , pp. 3401-3407
    • Zoetendal, E.G.1
  • 46
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg, P. B. et al. Diversity of the human intestinal microbial flora. Science 308, 1635-1638 (2005).
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1
  • 47
    • 33745628389 scopus 로고    scopus 로고
    • Probiotic use in clinical practice what are the risks
    • Boyle, R. J., Robins-Browne, R. M., Tang, M. L. Probiotic use in clinical practice: what are the risks Am J Clin Nutr 83, 1256-1264 (2006).
    • (2006) Am J Clin Nutr , vol.83 , pp. 1256-1264
    • Boyle, R.J.1    Robins-Browne, R.M.2    Tang, M.L.3
  • 48
    • 79957576718 scopus 로고    scopus 로고
    • NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
    • Elinav, E. et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145, 745-757 (2011).
    • (2011) Cell , vol.145 , pp. 745-757
    • Elinav, E.1
  • 49
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • Garrett, W. S. et al. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell 131, 33-45 (2007).
    • (2007) Cell , vol.131 , pp. 33-45
    • Garrett, W.S.1
  • 50
    • 33745309891 scopus 로고    scopus 로고
    • Use of a probiotic to control lactococcosis and streptococcosis in rainbow trout, Oncorhynchus mykiss (Walbaum)
    • Brunt, J., Austin, B. Use of a probiotic to control lactococcosis and streptococcosis in rainbow trout, Oncorhynchus mykiss (Walbaum). J Fish Dis 28, 693-701 (2005).
    • (2005) J Fish Dis , vol.28 , pp. 693-701
    • Brunt, J.1    Austin, B.2
  • 51
    • 49349096734 scopus 로고    scopus 로고
    • Immune responses and enhanced disease resistance in Chinese drum, Miichthys miiuy (Basilewsky), after oral administration of live or dead cells of Clostridium butyrium CB2
    • Pan, X., Wu, T., Song, Z., Tang, H., Zhao, Z. Immune responses and enhanced disease resistance in Chinese drum, Miichthys miiuy (Basilewsky), after oral administration of live or dead cells of Clostridium butyrium CB2. J Fish Dis 31, 679-686 (2008).
    • (2008) J Fish Dis , vol.31 , pp. 679-686
    • Pan, X.1    Wu, T.2    Song, Z.3    Tang, H.4    Zhao, Z.5
  • 52
    • 84956588503 scopus 로고
    • A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum
    • Bessey, O. A., Lowry, O. H., Brock, M. J. A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum. J Biol Chem 164, 321-329 (1946).
    • (1946) J Biol Chem , vol.164 , pp. 321-329
    • Bessey, O.A.1    Lowry, O.H.2    Brock, M.J.3
  • 53
    • 2442510059 scopus 로고    scopus 로고
    • Improved extraction of PCR-quality community DNA from digesta and fecal samples
    • Yu, Z., Morrison, M. Improved extraction of PCR-quality community DNA from digesta and fecal samples. BioTechniques 36, 808-812 (2004).
    • (2004) BioTechniques , vol.36 , pp. 808-812
    • Yu, Z.1    Morrison, M.2
  • 54
    • 78650974289 scopus 로고    scopus 로고
    • Effects of dietary antibiotic growth promoter and fermentation product on production, intestinal bacterial community, and nonspecific immunity of hybrid tilapia (female male)
    • He, S. et al. Effects of dietary antibiotic growth promoter and fermentation product on production, intestinal bacterial community, and nonspecific immunity of hybrid tilapia (female male). J Anim Sci 89, 84-92 (2011).
    • (2011) J Anim Sci , vol.89 , pp. 84-92
    • He, S.1
  • 55
    • 80054052509 scopus 로고    scopus 로고
    • Metagenomic profile of the bacterial communities associated with Ixodes ricinus ticks
    • Carpi, G. et al. Metagenomic profile of the bacterial communities associated with Ixodes ricinus ticks. PloS One 6, e25604-e25604 (2011).
    • (2011) PloS One , vol.6 , pp. e25604-e25604
    • Carpi, G.1
  • 56
    • 77952243141 scopus 로고    scopus 로고
    • QIIME allows analysis of high-throughput community sequencing data
    • Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods 7, 335-336 (2010).
    • (2010) Nat Methods , vol.7 , pp. 335-336
    • Caporaso, J.G.1
  • 57
    • 33947269742 scopus 로고    scopus 로고
    • Quantitative and qualitative diversity measures lead to different insights into factors that structure microbial communities
    • Lozupone, C. A., Hamady, M., Kelley, S. T., Knight, R. Quantitative and qualitative diversity measures lead to different insights into factors that structure microbial communities. Appl Environ Microbiol 73, 1576-1585 (2007).
    • (2007) Appl Environ Microbiol , vol.73 , pp. 1576-1585
    • Lozupone, C.A.1    Hamady, M.2    Kelley, S.T.3    Knight, R.4
  • 58
    • 84884227116 scopus 로고    scopus 로고
    • Neuroprotective effects of Huang-Lian-Jie-Du-Decoction on ischemic stroke rats revealed by 1 H NMR metabolomics approach
    • Wang, P. R., Wang, J. S., Yang, M. H., Kong, L. Y. Neuroprotective effects of Huang-Lian-Jie-Du-Decoction on ischemic stroke rats revealed by 1 H NMR metabolomics approach. J Pharm Biomed Anal 88, 106-116 (2014).
    • (2014) J Pharm Biomed Anal , vol.88 , pp. 106-116
    • Wang, P.R.1    Wang, J.S.2    Yang, M.H.3    Kong, L.Y.4
  • 59
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K. J., Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408, doi: 10.1006/meth.2001.1262 (2001).
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 60
    • 84908365373 scopus 로고    scopus 로고
    • Effects of zinc oxide supported on zeolite on growth performance, intestinal barrier function and digestive enzyme activities of Nile tilapia
    • Hu, C., Xiao, K., Jiao, L., Song, J. Effects of zinc oxide supported on zeolite on growth performance, intestinal barrier function and digestive enzyme activities of Nile tilapia. Aquacult Nutr 20, 486-493 (2014).
    • (2014) Aquacult Nutr , vol.20 , pp. 486-493
    • Hu, C.1    Xiao, K.2    Jiao, L.3    Song, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.