메뉴 건너뛰기




Volumn 6, Issue 10, 2011, Pages

Metagenomic profile of the bacterial communities associated with Ixodes ricinus ticks

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; RIBOSOME RNA; RNA 16S; COMPLEMENTARY DNA;

EID: 80054052509     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025604     Document Type: Article
Times cited : (226)

References (53)
  • 1
    • 33646566554 scopus 로고    scopus 로고
    • Tick-Borne Disease of Humans
    • Washington, DC, ASM press
    • Goodman J, Dennis D, Sonenshine D, (2005) Tick-Borne Disease of Humans. Washington, DC ASM press.
    • (2005)
    • Goodman, J.1    Dennis, D.2    Sonenshine, D.3
  • 2
    • 67649556676 scopus 로고    scopus 로고
    • Epidemiology of lyme borreliosis
    • Hubalek Z, (2009) Epidemiology of lyme borreliosis. Curr Probl Dermatol 37: 31-50.
    • (2009) Curr Probl Dermatol , vol.37 , pp. 31-50
    • Hubalek, Z.1
  • 3
    • 0035867078 scopus 로고    scopus 로고
    • Ticks and tickborne bacterial diseases in humans: an emerging infectious threat
    • Parola P, Raoult D, (2001) Ticks and tickborne bacterial diseases in humans: an emerging infectious threat. Clin Infect Dis 32: 897-928.
    • (2001) Clin Infect Dis , vol.32 , pp. 897-928
    • Parola, P.1    Raoult, D.2
  • 4
    • 0030879879 scopus 로고    scopus 로고
    • Endosymbionts of ticks and their relationship to Wolbachia spp. and tick-borne pathogens of humans and animals
    • Noda H, Munderloh UG, Kurtti TJ, (1997) Endosymbionts of ticks and their relationship to Wolbachia spp. and tick-borne pathogens of humans and animals. Appl Environ Microbiol 63: 3926-3932.
    • (1997) Appl Environ Microbiol , vol.63 , pp. 3926-3932
    • Noda, H.1    Munderloh, U.G.2    Kurtti, T.J.3
  • 5
    • 43249124717 scopus 로고    scopus 로고
    • Midichloria mitochondrii is widespread in hard ticks (Ixodidae) and resides in the mitochondria of phylogenetically diverse species
    • Epis S, Sassera D, Beninati T, Lo N, Beati L, et al. (2008) Midichloria mitochondrii is widespread in hard ticks (Ixodidae) and resides in the mitochondria of phylogenetically diverse species. Parasitology 135: 485-494.
    • (2008) Parasitology , vol.135 , pp. 485-494
    • Epis, S.1    Sassera, D.2    Beninati, T.3    Lo, N.4    Beati, L.5
  • 6
    • 33646202174 scopus 로고    scopus 로고
    • Broad-range PCR-TTGE for the first-line detection of bacterial pathogen DNA in ticks
    • Halos L, Mavris M, Vourc'h G, Maillard R, Barnouin J, et al. (2006) Broad-range PCR-TTGE for the first-line detection of bacterial pathogen DNA in ticks. Vet Res 37: 245-253.
    • (2006) Vet Res , vol.37 , pp. 245-253
    • Halos, L.1    Mavris, M.2    Vourc'h, G.3    Maillard, R.4    Barnouin, J.5
  • 8
    • 0037290241 scopus 로고    scopus 로고
    • Application of broad-range 16S rRNA PCR amplification and DGGE fingerprinting for detection of tick-infecting bacteria
    • Schabereiter-Gurtner C, Lubitz W, Rolleke S, (2003) Application of broad-range 16S rRNA PCR amplification and DGGE fingerprinting for detection of tick-infecting bacteria. J Microbiol Methods 52: 251-260.
    • (2003) J Microbiol Methods , vol.52 , pp. 251-260
    • Schabereiter-Gurtner, C.1    Lubitz, W.2    Rolleke, S.3
  • 12
    • 66149101252 scopus 로고    scopus 로고
    • Metagenomic analyses of viruses in stool samples from children with acute flaccid paralysis
    • Victoria JG, Kapoor A, Li L, Blinkova O, Slikas B, et al. (2009) Metagenomic analyses of viruses in stool samples from children with acute flaccid paralysis. J Virol 83: 4642-4651.
    • (2009) J Virol , vol.83 , pp. 4642-4651
    • Victoria, J.G.1    Kapoor, A.2    Li, L.3    Blinkova, O.4    Slikas, B.5
  • 13
    • 35348853758 scopus 로고    scopus 로고
    • A metagenomic survey of microbes in honey bee colony collapse disorder
    • Cox-Foster DL, Conlan S, Holmes EC, Palacios G, Evans JD, et al. (2007) A metagenomic survey of microbes in honey bee colony collapse disorder. Science 318: 283-287.
    • (2007) Science , vol.318 , pp. 283-287
    • Cox-Foster, D.L.1    Conlan, S.2    Holmes, E.C.3    Palacios, G.4    Evans, J.D.5
  • 14
    • 78149448867 scopus 로고    scopus 로고
    • Nodeomics: pathogen detection in vertebrate lymph nodes using meta-transcriptomics
    • Wittekindt NE, Padhi A, Schuster SC, Qi J, Zhao F, et al. (2010) Nodeomics: pathogen detection in vertebrate lymph nodes using meta-transcriptomics. PLoS One 5: e13432.
    • (2010) PLoS One , vol.5
    • Wittekindt, N.E.1    Padhi, A.2    Schuster, S.C.3    Qi, J.4    Zhao, F.5
  • 16
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • Dethlefsen L, Huse S, Sogin ML, Relman DA, (2008) The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol 6: e280.
    • (2008) PLoS Biol , vol.6
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4
  • 17
    • 69249109724 scopus 로고    scopus 로고
    • Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine
    • Claesson MJ, O'Sullivan O, Wang Q, Nikkila J, Marchesi JR, et al. (2009) Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One 4: e6669.
    • (2009) PLoS One , vol.4
    • Claesson, M.J.1    O'Sullivan, O.2    Wang, Q.3    Nikkila, J.4    Marchesi, J.R.5
  • 18
    • 34547961859 scopus 로고    scopus 로고
    • Using genomic approaches to unravel livestock (host)-tick-pathogen interactions
    • Jensen K, de Miranda Santos IK, Glass EJ, (2007) Using genomic approaches to unravel livestock (host)-tick-pathogen interactions. Trends Parasitol 23: 439-444.
    • (2007) Trends Parasitol , vol.23 , pp. 439-444
    • Jensen, K.1    de Miranda Santos, I.K.2    Glass, E.J.3
  • 19
    • 33645828181 scopus 로고    scopus 로고
    • A study of the presence of B. burgdorferi, Anaplasma (previously Ehrlichia) phagocytophilum, Rickettsia, and Babesia in Ixodes ricinus collected within the territory of Belluno, Italy
    • Piccolin G, Benedetti G, Doglioni C, Lorenzato C, Mancuso S, et al. (2006) A study of the presence of B. burgdorferi, Anaplasma (previously Ehrlichia) phagocytophilum, Rickettsia, and Babesia in Ixodes ricinus collected within the territory of Belluno, Italy. Vector Borne Zoonotic Dis 6: 24-31.
    • (2006) Vector Borne Zoonotic Dis , vol.6 , pp. 24-31
    • Piccolin, G.1    Benedetti, G.2    Doglioni, C.3    Lorenzato, C.4    Mancuso, S.5
  • 20
    • 65249180016 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum groEL gene heterogeneity in Ixodes ricinus larvae feeding on roe deer in Northeastern Italy
    • Carpi G, Bertolotti L, Pecchioli E, Cagnacci F, Rizzoli A, (2009) Anaplasma phagocytophilum groEL gene heterogeneity in Ixodes ricinus larvae feeding on roe deer in Northeastern Italy. Vector Borne Zoonotic Dis 9: 179-184.
    • (2009) Vector Borne Zoonotic Dis , vol.9 , pp. 179-184
    • Carpi, G.1    Bertolotti, L.2    Pecchioli, E.3    Cagnacci, F.4    Rizzoli, A.5
  • 21
    • 3242722804 scopus 로고    scopus 로고
    • Fauna d'Italia. Acari Ixodida
    • Bologna, Italy, Calderini
    • Manilla G, (1998) Fauna d'Italia. Acari Ixodida. Bologna, Italy Calderini.
    • (1998)
    • Manilla, G.1
  • 22
    • 84881261699 scopus 로고    scopus 로고
    • Forest structure and roe deer abundance predict tick-borne encephalitis risk in Italy
    • Rizzoli A, Hauffe HC, Tagliapietra V, Neteler M, Rosa R, (2009) Forest structure and roe deer abundance predict tick-borne encephalitis risk in Italy. PLoS One 4: e4336.
    • (2009) PLoS One , vol.4
    • Rizzoli, A.1    Hauffe, H.C.2    Tagliapietra, V.3    Neteler, M.4    Rosa, R.5
  • 23
    • 16844377216 scopus 로고    scopus 로고
    • Borrelia burgdorferi sensu lato infection in larval Ixodes ricinus (Acari: Ixodidae) feeding on blackbirds in northwestern Italy
    • Mannelli A, Nebbia P, Tramuta C, Grego E, Tomassone L, et al. (2005) Borrelia burgdorferi sensu lato infection in larval Ixodes ricinus (Acari: Ixodidae) feeding on blackbirds in northwestern Italy. J Med Entomol 42: 168-175.
    • (2005) J Med Entomol , vol.42 , pp. 168-175
    • Mannelli, A.1    Nebbia, P.2    Tramuta, C.3    Grego, E.4    Tomassone, L.5
  • 24
    • 0028839379 scopus 로고
    • Simultaneous detection and genotyping of three genomic groups of Borrelia burgdorferi sensu lato in Dutch Ixodes ricinus ticks by characterization of the amplified intergenic spacer region between 5S and 23S rRNA genes
    • Rijpkema SG, Molkenboer MJ, Schouls LM, Jongejan F, Schellekens JF, (1995) Simultaneous detection and genotyping of three genomic groups of Borrelia burgdorferi sensu lato in Dutch Ixodes ricinus ticks by characterization of the amplified intergenic spacer region between 5S and 23S rRNA genes. J Clin Microbiol 33: 3091-3095.
    • (1995) J Clin Microbiol , vol.33 , pp. 3091-3095
    • Rijpkema, S.G.1    Molkenboer, M.J.2    Schouls, L.M.3    Jongejan, F.4    Schellekens, J.F.5
  • 25
    • 68549109626 scopus 로고    scopus 로고
    • A new Borrelia species defined by multilocus sequence analysis of housekeeping genes
    • Margos G, Vollmer SA, Cornet M, Garnier M, Fingerle V, et al. (2009) A new Borrelia species defined by multilocus sequence analysis of housekeeping genes. Appl Environ Microbiol 75: 5410-5416.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 5410-5416
    • Margos, G.1    Vollmer, S.A.2    Cornet, M.3    Garnier, M.4    Fingerle, V.5
  • 26
    • 13244255415 scopus 로고    scopus 로고
    • MUSCLE: a multiple sequence alignment method with reduced time and space complexity
    • Edgar RC, (2004) MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5: 113.
    • (2004) BMC Bioinformatics , vol.5 , pp. 113
    • Edgar, R.C.1
  • 27
    • 0031773680 scopus 로고    scopus 로고
    • MODELTEST: testing the model of DNA substitution
    • Posada D, Crandall KA, (1998) MODELTEST: testing the model of DNA substitution. Bioinformatics 14: 817-818.
    • (1998) Bioinformatics , vol.14 , pp. 817-818
    • Posada, D.1    Crandall, K.A.2
  • 28
    • 0041386108 scopus 로고    scopus 로고
    • MrBayes 3: Bayesian phylogenetic inference under mixed models
    • Ronquist F, Huelsenbeck JP, (2003) MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19: 1572-1574.
    • (2003) Bioinformatics , vol.19 , pp. 1572-1574
    • Ronquist, F.1    Huelsenbeck, J.P.2
  • 29
    • 34848867598 scopus 로고    scopus 로고
    • Whole-genome shotgun sequencing of mitochondria from ancient hair shafts
    • Gilbert MT, Tomsho LP, Rendulic S, Packard M, Drautz DI, et al. (2007) Whole-genome shotgun sequencing of mitochondria from ancient hair shafts. Science 317: 1927-1930.
    • (2007) Science , vol.317 , pp. 1927-1930
    • Gilbert, M.T.1    Tomsho, L.P.2    Rendulic, S.3    Packard, M.4    Drautz, D.I.5
  • 30
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3    Zhang, J.4    Zhang, Z.5
  • 32
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li H, Durbin R, (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 33
    • 75249099173 scopus 로고    scopus 로고
    • inGAP: an integrated next-generation genome analysis pipeline
    • Qi J, Zhao F, Buboltz A, Schuster SC, (2010) inGAP: an integrated next-generation genome analysis pipeline. Bioinformatics 26: 127-129.
    • (2010) Bioinformatics , vol.26 , pp. 127-129
    • Qi, J.1    Zhao, F.2    Buboltz, A.3    Schuster, S.C.4
  • 34
    • 34147182303 scopus 로고    scopus 로고
    • A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria
    • Chakravorty S, Helb D, Burday M, Connell N, Alland D, (2007) A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria. J Microbiol Methods 69: 330-339.
    • (2007) J Microbiol Methods , vol.69 , pp. 330-339
    • Chakravorty, S.1    Helb, D.2    Burday, M.3    Connell, N.4    Alland, D.5
  • 35
    • 58149200948 scopus 로고    scopus 로고
    • The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
    • Cole JR, Wang Q, Cardenas E, Fish J, Chai B, et al. (2009) The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic Acids Res 37: D141-145.
    • (2009) Nucleic Acids Res , vol.37
    • Cole, J.R.1    Wang, Q.2    Cardenas, E.3    Fish, J.4    Chai, B.5
  • 36
    • 0001515328 scopus 로고
    • On the Measurement of Niche Breadth and Overlap
    • Colwell RK, Futuyma DJ, (1971) On the Measurement of Niche Breadth and Overlap. Ecology 52: 567-576.
    • (1971) Ecology , vol.52 , pp. 567-576
    • Colwell, R.K.1    Futuyma, D.J.2
  • 37
    • 0343315188 scopus 로고
    • Detrended Correspondence Analysis: An Improved Ordination Technique
    • Hill MO, Gauch HG, (1980) Detrended Correspondence Analysis: An Improved Ordination Technique. Vegetatio 42: 47-58.
    • (1980) Vegetatio , vol.42 , pp. 47-58
    • Hill, M.O.1    Gauch, H.G.2
  • 38
    • 0002521330 scopus 로고
    • Ordination
    • In: Jongman RHG, ter Braak CJF, van Tongeren OFR, editors, Cambridge, Cambridge University Press
    • ter Braak CJF, (1995) Ordination. In: Jongman RHG, ter Braak CJF, van Tongeren OFR, editors. Data analysis in community and landscape ecology Cambridge Cambridge University Press pp. 91-173.
    • (1995) Data Analysis in Community and Landscape Ecology , pp. 91-173
    • ter Braak, C.J.F.1
  • 39
    • 0023482416 scopus 로고
    • The analysis of vegetation-environment relationships by canonical correspondence analysis
    • ter Braak CJF, (1987) The analysis of vegetation-environment relationships by canonical correspondence analysis. Vegetatio 69: 69-77.
    • (1987) Vegetatio , vol.69 , pp. 69-77
    • ter Braak, C.J.F.1
  • 40
    • 0022843649 scopus 로고
    • Canonical correspondence analysis: a new eigenvector technique for multivariate direct gradient analysis
    • ter Braak CJF, (1986) Canonical correspondence analysis: a new eigenvector technique for multivariate direct gradient analysis. Ecology 67: 1167-1179.
    • (1986) Ecology , vol.67 , pp. 1167-1179
    • ter Braak, C.J.F.1
  • 42
    • 33645451883 scopus 로고    scopus 로고
    • Molecular analysis of microbial communities identified in different developmental stages of Ixodes scapularis ticks from Westchester and Dutchess Counties, New York
    • Moreno CX, Moy F, Daniels TJ, Godfrey HP, Cabello FC, (2006) Molecular analysis of microbial communities identified in different developmental stages of Ixodes scapularis ticks from Westchester and Dutchess Counties, New York. Environ Microbiol 8: 761-772.
    • (2006) Environ Microbiol , vol.8 , pp. 761-772
    • Moreno, C.X.1    Moy, F.2    Daniels, T.J.3    Godfrey, H.P.4    Cabello, F.C.5
  • 43
    • 77949279987 scopus 로고    scopus 로고
    • Bacterial diversity in Amblyomma americanum (Acari: Ixodidae) with a focus on members of the genus Rickettsia
    • Heise SR, Elshahed MS, Little SE, (2010) Bacterial diversity in Amblyomma americanum (Acari: Ixodidae) with a focus on members of the genus Rickettsia. J Med Entomol 47: 258-268.
    • (2010) J Med Entomol , vol.47 , pp. 258-268
    • Heise, S.R.1    Elshahed, M.S.2    Little, S.E.3
  • 44
    • 78650876390 scopus 로고    scopus 로고
    • Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplus through tag-encoded pyrosequencing
    • Andreotti R, Perez de Leon AA, Dowd SE, Guerrero FD, Bendele KG, et al. (2011) Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplus through tag-encoded pyrosequencing. BMC Microbiol 11: 6.
    • (2011) BMC Microbiol , vol.11 , pp. 6
    • Andreotti, R.1    Perez de Leon, A.A.2    Dowd, S.E.3    Guerrero, F.D.4    Bendele, K.G.5
  • 45
    • 77958489367 scopus 로고    scopus 로고
    • Pathogenic landscapes: interactions between land, people, disease vectors, and their animal hosts
    • Lambin EF, Tran A, Vanwambeke SO, Linard C, Soti V, (2010) Pathogenic landscapes: interactions between land, people, disease vectors, and their animal hosts. Int J Health Geogr 9: 54.
    • (2010) Int J Health Geogr , vol.9 , pp. 54
    • Lambin, E.F.1    Tran, A.2    Vanwambeke, S.O.3    Linard, C.4    Soti, V.5
  • 46
    • 0032722408 scopus 로고    scopus 로고
    • Wolbachia pipientis: microbial manipulator of arthropod reproduction
    • Stouthamer R, Breeuwer JA, Hurst GD, (1999) Wolbachia pipientis: microbial manipulator of arthropod reproduction. Annu Rev Microbiol 53: 71-102.
    • (1999) Annu Rev Microbiol , vol.53 , pp. 71-102
    • Stouthamer, R.1    Breeuwer, J.A.2    Hurst, G.D.3
  • 47
    • 5544281906 scopus 로고    scopus 로고
    • Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks
    • Kawahara M, Rikihisa Y, Isogai E, Takahashi M, Misumi H, et al. (2004) Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. Int J Syst Evol Microbiol 54: 1837-1843.
    • (2004) Int J Syst Evol Microbiol , vol.54 , pp. 1837-1843
    • Kawahara, M.1    Rikihisa, Y.2    Isogai, E.3    Takahashi, M.4    Misumi, H.5
  • 49
    • 52649155001 scopus 로고    scopus 로고
    • Microbial communities and interactions in the lone star tick, Amblyomma americanum
    • Clay K, Klyachko O, Grindle N, Civitello D, Oleske D, et al. (2008) Microbial communities and interactions in the lone star tick, Amblyomma americanum. Mol Ecol 17: 4371-4381.
    • (2008) Mol Ecol , vol.17 , pp. 4371-4381
    • Clay, K.1    Klyachko, O.2    Grindle, N.3    Civitello, D.4    Oleske, D.5
  • 50
    • 77954432099 scopus 로고    scopus 로고
    • Septicemia caused by tick-borne bacterial pathogen Candidatus Neoehrlichia mikurensis
    • Fehr JS, Bloemberg GV, Ritter C, Hombach M, Luscher TF, et al. (2010) Septicemia caused by tick-borne bacterial pathogen Candidatus Neoehrlichia mikurensis. Emerg Infect Dis 16: 1127-1129.
    • (2010) Emerg Infect Dis , vol.16 , pp. 1127-1129
    • Fehr, J.S.1    Bloemberg, G.V.2    Ritter, C.3    Hombach, M.4    Luscher, T.F.5
  • 51
    • 77954438808 scopus 로고    scopus 로고
    • Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant
    • von Loewenich FD, Geissdorfer W, Disque C, Matten J, Schett G, et al. (2010) Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant. J Clin Microbiol 48: 2630-2635.
    • (2010) J Clin Microbiol , vol.48 , pp. 2630-2635
    • von Loewenich, F.D.1    Geissdorfer, W.2    Disque, C.3    Matten, J.4    Schett, G.5
  • 52
    • 0036833642 scopus 로고    scopus 로고
    • Rickettsial infection in Dermacentor variabilis (Acari: Ixodidae) inhibits transovarial transmission of a second Rickettsia
    • Macaluso KR, Sonenshine DE, Ceraul SM, Azad AF, (2002) Rickettsial infection in Dermacentor variabilis (Acari: Ixodidae) inhibits transovarial transmission of a second Rickettsia. J Med Entomol 39: 809-813.
    • (2002) J Med Entomol , vol.39 , pp. 809-813
    • Macaluso, K.R.1    Sonenshine, D.E.2    Ceraul, S.M.3    Azad, A.F.4
  • 53
    • 0037249618 scopus 로고    scopus 로고
    • Infection exclusion of the rickettsial pathogen anaplasma marginale in the tick vector Dermacentor variabilis
    • de la Fuente J, Blouin EF, Kocan KM, (2003) Infection exclusion of the rickettsial pathogen anaplasma marginale in the tick vector Dermacentor variabilis. Clin Diagn Lab Immunol 10: 182-184.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 182-184
    • de la Fuente, J.1    Blouin, E.F.2    Kocan, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.