-
1
-
-
77953032534
-
Emerging paradigms of regulated microRNA processing
-
Newman, M. A., Hammond, S. M. Emerging paradigms of regulated microRNA processing. Genes Dev. 24, 1086-1092 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 1086-1092
-
-
Newman, M.A.1
Hammond, S.M.2
-
2
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol, J., Loedige, I., Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
3
-
-
84893628843
-
Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates
-
Kelnar, K., Peltier, H., Leatherbury, N., Stoudemire, J., Bader, A. G. Quantification of therapeutic miRNA mimics in whole blood from nonhuman primates. Anal. Chem. 86, 1534-1542 (2014).
-
(2014)
Anal. Chem.
, vol.86
, pp. 1534-1542
-
-
Kelnar, K.1
Peltier, H.2
Leatherbury, N.3
Stoudemire, J.4
Bader, A.G.5
-
4
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
-
Chang, T. C. et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 26, 745-752 (2007).
-
(2007)
Mol. Cell
, vol.26
, pp. 745-752
-
-
Chang, T.C.1
-
5
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He, L. et al. A microRNA component of the p53 tumour suppressor network. Nature 447, 1130-1134 (2007).
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
-
6
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira, N. et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol. Cell 26, 731-743 (2007).
-
(2007)
Mol. Cell
, vol.26
, pp. 731-743
-
-
Raver-Shapira, N.1
-
7
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
Hermeking, H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 17, 193-199 (2009).
-
(2009)
Cell Death Differ.
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
8
-
-
37749036293
-
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability
-
Miska, E. A. et al. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet. 3, e215 (2007).
-
(2007)
PLoS Genet.
, vol.3
, pp. e215
-
-
Miska, E.A.1
-
9
-
-
84861116472
-
A resource for the conditional ablation of microRNAs in the mouse
-
Park, C. Y. et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 1, 385-391 (2012).
-
(2012)
Cell Rep.
, vol.1
, pp. 385-391
-
-
Park, C.Y.1
-
10
-
-
78649378267
-
MicroRNA functions in stress responses
-
Leung, A. K., Sharp, P. A. MicroRNA functions in stress responses. Mol. Cell 40, 205-215 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 205-215
-
-
Leung, A.K.1
Sharp, P.A.2
-
11
-
-
67649979858
-
The mir-34 microRNA is required for the DNA damage response in vivo in C. Elegans and in vitro in human breast cancer cells
-
Kato, M. et al. The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells. Oncogene 28, 2419-2424 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 2419-2424
-
-
Kato, M.1
-
12
-
-
84939440209
-
Robust distal tip cell pathfinding in the face of temperature stress is ensured by two conserved microRNAs in Caenorhabditis elegans
-
Burke, S., Hammell, M., Ambros, V. Robust distal tip cell pathfinding in the face of temperature stress is ensured by two conserved microRNAs in Caenorhabditis elegans. Genetics 200, 1201-1218 (2015).
-
(2015)
Genetics
, vol.200
, pp. 1201-1218
-
-
Burke, S.1
Hammell, M.2
Ambros, V.3
-
13
-
-
79955913660
-
MiR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner
-
Bandi, N., Vassella, E. miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Mol. Cancer 10, 55 (2011).
-
(2011)
Mol. Cancer
, vol.10
, pp. 55
-
-
Bandi, N.1
Vassella, E.2
-
14
-
-
81755163085
-
Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling
-
Lal, A. et al. Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet. 7, e1002363 (2011).
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002363
-
-
Lal, A.1
-
15
-
-
53949090314
-
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
-
Ji, Q. et al. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 8, 266 (2008).
-
(2008)
BMC Cancer
, vol.8
, pp. 266
-
-
Ji, Q.1
-
16
-
-
34547458550
-
P53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
Bommer, G. T. et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr. Biol. 17, 1298-1307 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 1298-1307
-
-
Bommer, G.T.1
-
17
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
18
-
-
0344668836
-
Human let-7 stem-loop precursors harbor features of RNase III cleavage products
-
Basyuk, E., Suavet, F., Doglio, A., Bordonne, R., Bertrand, E. Human let-7 stem-loop precursors harbor features of RNase III cleavage products. Nucleic Acids Res. 31, 6593-6597 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6593-6597
-
-
Basyuk, E.1
Suavet, F.2
Doglio, A.3
Bordonne, R.4
Bertrand, E.5
-
19
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNase III
-
Zhang, H., Kolb, F. A., Jaskiewicz, L., Westhof, E., Filipowicz, W. Single processing center models for human Dicer and bacterial RNase III. Cell 118, 57-68 (2004).
-
(2004)
Cell
, vol.118
, pp. 57-68
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
-
20
-
-
18744407284
-
Purified Argonaute2 and an siRNA form recombinant human RISC
-
Rivas, F. V. et al. Purified Argonaute2 and an siRNA form recombinant human RISC. Nat. Struct. Mol. Biol. 12, 340-349 (2005).
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 340-349
-
-
Rivas, F.V.1
-
21
-
-
15844371219
-
Structural basis for 5'-end-specific recognition of guide RNA by the A. Fulgidus Piwi protein
-
Ma, J. B. et al. Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434, 666-670 (2005).
-
(2005)
Nature
, vol.434
, pp. 666-670
-
-
Ma, J.B.1
-
22
-
-
84861451595
-
The crystal structure of human Argonaute2
-
Schirle, N. T., MacRae, I. J. The crystal structure of human Argonaute2. Science 336, 1037-1040 (2012).
-
(2012)
Science
, vol.336
, pp. 1037-1040
-
-
Schirle, N.T.1
MacRae, I.J.2
-
23
-
-
84863624199
-
The structure of human argonaute-2 in complex with miR-20a
-
Elkayam, E. et al. The structure of human argonaute-2 in complex with miR-20a. Cell 150, 100-110 (2012).
-
(2012)
Cell
, vol.150
, pp. 100-110
-
-
Elkayam, E.1
-
24
-
-
0035253615
-
ATM and ATR: Networking cellular responses to DNA damage
-
Shiloh, Y. ATM and ATR: networking cellular responses to DNA damage. Curr. Opin. Genet. Dev. 11, 71-77 (2001).
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 71-77
-
-
Shiloh, Y.1
-
25
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson, S. P., Bartek, J. The DNA-damage response in human biology and disease. Nature 461, 1071-1078 (2009).
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
26
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman, C. E. et al. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679 (1998).
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
-
27
-
-
0030797708
-
Recombinant ATM protein complements the cellular A-T phenotype
-
Ziv, Y. et al. Recombinant ATM protein complements the cellular A-T phenotype. Oncogene 15, 159-167 (1997).
-
(1997)
Oncogene
, vol.15
, pp. 159-167
-
-
Ziv, Y.1
-
28
-
-
34248563036
-
The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs
-
Weitzer, S., Martinez, J. The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs. Nature 447, 222-226 (2007).
-
(2007)
Nature
, vol.447
, pp. 222-226
-
-
Weitzer, S.1
Martinez, J.2
-
29
-
-
37049019490
-
MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
-
Weidhaas, J. B. et al. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res. 67, 11111-11116 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 11111-11116
-
-
Weidhaas, J.B.1
-
30
-
-
33745632759
-
A Caenorhabditis elegans tissue model of radiation-induced reproductive cell death
-
Weidhaas, J. B., Eisenmann, D. M., Holub, J. M., Nallur, S. V. A Caenorhabditis elegans tissue model of radiation-induced reproductive cell death. Proc. Natl Acad. Sci. USA 103, 9946-9951 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 9946-9951
-
-
Weidhaas, J.B.1
Eisenmann, D.M.2
Holub, J.M.3
Nallur, S.V.4
-
31
-
-
33751304712
-
A conserved RAS/mitogen-activated protein kinase pathway regulates DNA damage-induced cell death postirradiation in Radelegans
-
Weidhaas, J. B., Eisenmann, D. M., Holub, J. M., Nallur, S. V. A conserved RAS/mitogen-activated protein kinase pathway regulates DNA damage-induced cell death postirradiation in Radelegans. Cancer Res. 66, 10434-10438 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 10434-10438
-
-
Weidhaas, J.B.1
Eisenmann, D.M.2
Holub, J.M.3
Nallur, S.V.4
-
32
-
-
79951500251
-
The ATM kinase induces microRNA biogenesis in the DNA damage response
-
Zhang, X., Wan, G., Berger, F. G., He, X., Lu, X. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol. Cell 41, 371-383 (2012).
-
(2012)
Mol. Cell
, vol.41
, pp. 371-383
-
-
Zhang, X.1
Wan, G.2
Berger, F.G.3
He, X.4
Lu, X.5
-
33
-
-
84859382730
-
MicroRNA regulation of inflammatory responses
-
O'Connell, R. M., Rao, D. S., Baltimore, D. microRNA regulation of inflammatory responses. Annu. Rev. Immunol. 30, 295-312 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 295-312
-
-
O'Connell, R.M.1
Rao, D.S.2
Baltimore, D.3
-
34
-
-
84885189895
-
EGFR gets in the way of microRNA biogenesis
-
Nishida, N., Mimori, K., Mori, M., Calin, G. A. EGFR gets in the way of microRNA biogenesis. Cell Res. 23, 1157-1158 (2013).
-
(2013)
Cell Res.
, vol.23
, pp. 1157-1158
-
-
Nishida, N.1
Mimori, K.2
Mori, M.3
Calin, G.A.4
-
35
-
-
84878108145
-
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
-
Shen, J. et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature 497, 383-387 (2013).
-
(2013)
Nature
, vol.497
, pp. 383-387
-
-
Shen, J.1
-
36
-
-
59149091637
-
MicroRNA regulation of DNA repair gene expression in hypoxic stress
-
Crosby, M. E., Kulshreshtha, R., Ivan, M., Glazer, P. M. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 69, 1221-1229 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 1221-1229
-
-
Crosby, M.E.1
Kulshreshtha, R.2
Ivan, M.3
Glazer, P.M.4
-
37
-
-
84861443457
-
MicroRNA factory: RISC assembly from precursor microRNAs
-
Kim, Y., Kim, V. N. MicroRNA factory: RISC assembly from precursor microRNAs. Mol. Cell 46, 384-386 (2012).
-
(2012)
Mol. Cell
, vol.46
, pp. 384-386
-
-
Kim, Y.1
Kim, V.N.2
-
39
-
-
84879799948
-
DNA Damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway
-
Wan, G. et al. DNA Damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway. Cell Rep. 3, 2100-2112 (2013).
-
(2013)
Cell Rep.
, vol.3
, pp. 2100-2112
-
-
Wan, G.1
-
40
-
-
84867553154
-
Human RNA methyltransferase BCDIN3D regulates microRNA processing
-
Xhemalce, B., Robson, S., Kouzarides, T. Human RNA methyltransferase BCDIN3D regulates microRNA processing. Cell 151, 278-288 (2012).
-
(2012)
Cell
, vol.151
, pp. 278-288
-
-
Xhemalce, B.1
Robson, S.2
Kouzarides, T.3
-
41
-
-
84894609055
-
Mammalian 5'-capped microRNA precursors that generate a single microRNA
-
Xie, M. et al. Mammalian 5'-capped microRNA precursors that generate a single microRNA. Cell 155, 1568-1580 (2013).
-
(2013)
Cell
, vol.155
, pp. 1568-1580
-
-
Xie, M.1
-
42
-
-
77956277719
-
Purification of RNA using TRIzol (TRI reagent)
-
pdb prot5439
-
Rio, D. C., Ares, Jr. M., Hannon, G. J., Nilsen, T. W. Purification of RNA using TRIzol (TRI reagent). Cold Spring Harb. Protoc. 2010, pdb prot5439 (2010).
-
(2010)
Cold Spring Harb. Protoc.
, vol.2010
-
-
Rio, D.C.1
Ares, M.2
Hannon, G.J.3
Nilsen, T.W.4
-
43
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister, G. et al. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 15, 185-197 (2004).
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
|