메뉴 건너뛰기




Volumn 9, Issue 2, 2016, Pages 352-363

CD11c+ monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD64 ANTIGEN; GLYCOPROTEIN P 15095; INTERLEUKIN 23; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; ALPHA E INTEGRINS; ALPHA INTEGRIN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CLEC9A PROTEIN, MOUSE; FC RECEPTOR; HLA ANTIGEN CLASS 2; IMMUNOGLOBULIN RECEPTOR; LECTIN; LEUKOCYTE ANTIGEN; REPRESSOR PROTEIN; SNFT PROTEIN, MOUSE;

EID: 84961769001     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.65     Document Type: Article
Times cited : (107)

References (48)
  • 3
    • 84874069797 scopus 로고    scopus 로고
    • Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells
    • Cerovic V, et al. Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells. Mucosal Immunol. 6, 104-113 (2013).
    • (2013) Mucosal Immunol , vol.6 , pp. 104-113
    • Cerovic, V.1
  • 4
    • 84878167904 scopus 로고    scopus 로고
    • IRF4 transcription-factor-dependent CD103(+) CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation
    • Persson E.K, et al. IRF4 transcription-factor-dependent CD103(+) CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation. Immunity. 38, 958-969 (2013).
    • (2013) Immunity , vol.38 , pp. 958-969
    • Persson, E.K.1
  • 5
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes J.L, et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 204, 1757-1764 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1
  • 6
    • 79960513242 scopus 로고    scopus 로고
    • Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory Tcell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization
    • Denning T.L, et al. Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory Tcell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization. J. Immunol. 187, 733-747 (2011).
    • (2011) J. Immunol , vol.187 , pp. 733-747
    • Denning, T.L.1
  • 7
    • 80054754519 scopus 로고    scopus 로고
    • Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization
    • Edelson B.T, et al. Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. PLoS One. 6, e25660 (2011).
    • (2011) PLoS One , vol.6 , pp. e25660
    • Edelson, B.T.1
  • 8
    • 84872765982 scopus 로고    scopus 로고
    • Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
    • Yona S, et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 38, 79-91 (2013).
    • (2013) Immunity , vol.38 , pp. 79-91
    • Yona, S.1
  • 9
    • 51049092467 scopus 로고    scopus 로고
    • Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans
    • Jaensson E, et al. Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. J. Exp. Med. 205, 2139-2149 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 2139-2149
    • Jaensson, E.1
  • 10
    • 84921313153 scopus 로고    scopus 로고
    • Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
    • Bain C.C, et al. Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nat. Immunol. 15, 929-937 (2014).
    • (2014) Nat. Immunol , vol.15 , pp. 929-937
    • Bain, C.C.1
  • 11
    • 84876349699 scopus 로고    scopus 로고
    • Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors
    • Bain C.C, et al. Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunol. 6, 498-510 (2013).
    • (2013) Mucosal Immunol , vol.6 , pp. 498-510
    • Bain, C.C.1
  • 12
    • 84856815290 scopus 로고    scopus 로고
    • Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon
    • Rivollier A, He J, Kole A, Valatas V, & Kelsall B.L. Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J. Exp. Med. 209, 139-155 (2012).
    • (2012) J. Exp. Med , vol.209 , pp. 139-155
    • Rivollier, A.1    He, J.2    Kole, A.3    Valatas, V.4    Kelsall, B.L.5
  • 13
    • 84870900504 scopus 로고    scopus 로고
    • Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells
    • Zigmond E, et al. Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity. 37, 1076-1090 (2012).
    • (2012) Immunity , vol.37 , pp. 1076-1090
    • Zigmond, E.1
  • 14
    • 84871307366 scopus 로고    scopus 로고
    • CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis
    • Tamoutounour S, et al. CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. Eur. J. Immunol. 42, 3150-3166 (2012).
    • (2012) Eur. J. Immunol , vol.42 , pp. 3150-3166
    • Tamoutounour, S.1
  • 15
    • 84867740805 scopus 로고    scopus 로고
    • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
    • Gautier E.L, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13, 1118-1128 (2012).
    • (2012) Nat. Immunol , vol.13 , pp. 1118-1128
    • Gautier, E.L.1
  • 16
    • 77951934151 scopus 로고    scopus 로고
    • E-cadherin marks a subset of inflammatory dendritic cells that promote Tcell-mediated colitis
    • Siddiqui K.R, Laffont S, & Powrie F. E-cadherin marks a subset of inflammatory dendritic cells that promote Tcell-mediated colitis. Immunity. 32, 557-567 (2010).
    • (2010) Immunity , vol.32 , pp. 557-567
    • Siddiqui, K.R.1    Laffont, S.2    Powrie, F.3
  • 17
    • 84875225901 scopus 로고    scopus 로고
    • Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense
    • Farache J, Zigmond E, Shakhar, G, & Jung S. Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense. Immunol. Cell Biol. 91, 232-239 (2013).
    • (2013) Immunol. Cell Biol , vol.91 , pp. 232-239
    • Farache, J.1    Zigmond, E.2    Shakhar, G.3    Jung, S.4
  • 18
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann, B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 13, 715-725 (2000).
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1
  • 19
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr R.H, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 314, 1461-1463 (2006).
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1
  • 20
    • 33750505009 scopus 로고    scopus 로고
    • Interleukin-23 drives innate and T cell-mediated intestinal inflammation
    • Hue S, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J. Exp. Med. 203, 2473-2483 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 2473-2483
    • Hue, S.1
  • 21
    • 0032425062 scopus 로고    scopus 로고
    • Helicobacter hepaticus triggers colitis in specificpathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
    • Kullberg M.C, et al. Helicobacter hepaticus triggers colitis in specificpathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- And gamma interferon-dependent mechanism. Infect. Immun. 66, 5157-5166 (1998).
    • (1998) Infect. Immun , vol.66 , pp. 5157-5166
    • Kullberg, M.C.1
  • 22
    • 84883827165 scopus 로고    scopus 로고
    • Th17-cell plasticity in Helicobacter hepaticus-induced intestinal inflammation
    • Morrison P.J, et al. Th17-cell plasticity in Helicobacter hepaticus-induced intestinal inflammation. Mucosal Immunol. 6, 1143-1156 (2013).
    • (2013) Mucosal Immunol , vol.6 , pp. 1143-1156
    • Morrison, P.J.1
  • 23
    • 33750530394 scopus 로고    scopus 로고
    • IL-23 plays a key role in Helicobacter hepaticusinduced T cell-dependent colitis
    • Kullberg M.C, et al. IL-23 plays a key role in Helicobacter hepaticusinduced T cell-dependent colitis. J. Exp. Med. 203, 2485-2494 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 2485-2494
    • Kullberg, M.C.1
  • 24
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein M, Keshav S, Harris N, & Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287-292 (1992).
    • (1992) J. Exp. Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 25
    • 34248577055 scopus 로고    scopus 로고
    • Elimination of antigen-presenting cells and autoreactive Tcells by Fas contributes to prevention of autoimmunity
    • Stranges P.B, et al. Elimination of antigen-presenting cells and autoreactive Tcells by Fas contributes to prevention of autoimmunity. Immunity. 26, 629-641 (2007).
    • (2007) Immunity , vol.26 , pp. 629-641
    • Stranges, P.B.1
  • 26
    • 84871403211 scopus 로고    scopus 로고
    • PU.1 is essential for CD11c expression in CD8(+)/CD8(-) lymphoid and monocyte-derived dendritic cells during GM-CSF or FLT3L-induced differentiation
    • Zhu X.J, Yang Z.F., Chen Y., Wang J, & Rosmarin A.G. PU.1 is essential for CD11c expression in CD8(+)/CD8(-) lymphoid and monocyte-derived dendritic cells during GM-CSF or FLT3L-induced differentiation. PLoSOne. 7, e52141 (2012).
    • (2012) PLoSOne , vol.7 , pp. e52141
    • Zhu, X.J.1    Yang, Z.F.2    Chen, Y.3    Wang, J.4    Rosmarin, A.G.5
  • 27
    • 33846906914 scopus 로고    scopus 로고
    • IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis
    • Thakker, P, Leach, M.W., Kuang, W., Benoit S.E, Leonard J.P. & Marusic S. IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis. J. Immunol. 178, 2589-2598 (2007).
    • (2007) J. Immunol , vol.178 , pp. 2589-2598
    • Thakker, P.1    Leach, M.W.2    Kuang, W.3    Benoit, S.E.4    Leonard, J.P.5    Marusic, S.6
  • 28
    • 33646433989 scopus 로고    scopus 로고
    • Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
    • Chen Y, et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J. Clin. Invest. 116, 1317-1326 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 1317-1326
    • Chen, Y.1
  • 29
    • 77955890952 scopus 로고    scopus 로고
    • Interleukin-23 drives intestinal inflammation through direct activity on T cells
    • Ahern P.P, et al. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity. 33, 279-288 (2010).
    • (2010) Immunity , vol.33 , pp. 279-288
    • Ahern, P.P.1
  • 30
    • 56449097442 scopus 로고    scopus 로고
    • Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic Tcell immunity
    • Hildner K, et al. Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic Tcell immunity. Science. 322, 1097-1100 (2008).
    • (2008) Science , vol.322 , pp. 1097-1100
    • Hildner, K.1
  • 31
    • 79956068261 scopus 로고    scopus 로고
    • Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation
    • Hashimoto D, et al. Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J. Exp. Med. 208, 1069-1082 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 1069-1082
    • Hashimoto, D.1
  • 32
    • 78149462163 scopus 로고    scopus 로고
    • An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumorassociated macrophages but does not inhibit inflammation
    • MacDonald K.P, et al. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- And tumorassociated macrophages but does not inhibit inflammation. Blood. 116, 3955-3963 (2010).
    • (2010) Blood , vol.116 , pp. 3955-3963
    • MacDonald, K.P.1
  • 33
    • 77952784918 scopus 로고    scopus 로고
    • Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis
    • Sheikh S.Z, Matsuoka K, Kobayashi T, Li F, Rubinas T, & Plevy S.E. Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis. J. Immunol. 184, 4069-4073 (2010).
    • (2010) J. Immunol , vol.184 , pp. 4069-4073
    • Sheikh, S.Z.1    Matsuoka, K.2    Kobayashi, T.3    Li, F.4    Rubinas, T.5    Plevy, S.E.6
  • 34
    • 45749107055 scopus 로고    scopus 로고
    • Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis
    • Kamada N, et al. Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis. J. Clin. Invest. 118, 2269-2280 (2008).
    • (2008) J. Clin. Invest , vol.118 , pp. 2269-2280
    • Kamada, N.1
  • 35
    • 84905118660 scopus 로고    scopus 로고
    • CX(3)CR1(+) mononuclear phagocytes support colitis-Associated innate lymphoid cell production of IL-22
    • Longman R.S, et al. CX(3)CR1(+) mononuclear phagocytes support colitis-Associated innate lymphoid cell production of IL-22. J. Exp. Med. 211, 1571-1583 (2014).
    • (2014) J. Exp. Med , vol.211 , pp. 1571-1583
    • Longman, R.S.1
  • 36
    • 84900448316 scopus 로고    scopus 로고
    • Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis
    • Zigmond E, et al. Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis. Immunity. 40, 720-733 (2014).
    • (2014) Immunity , vol.40 , pp. 720-733
    • Zigmond, E.1
  • 37
    • 84884352076 scopus 로고    scopus 로고
    • Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes
    • Jakubzick C, et al. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity. 39, 599-610 (2013).
    • (2013) Immunity , vol.39 , pp. 599-610
    • Jakubzick, C.1
  • 38
    • 84878191150 scopus 로고    scopus 로고
    • IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
    • Schlitzer A, et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity. 38, 970-983 (2013).
    • (2013) Immunity , vol.38 , pp. 970-983
    • Schlitzer, A.1
  • 39
    • 84922714497 scopus 로고    scopus 로고
    • CCR2CD103 intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by Tcells
    • Scott C.L, et al. CCR2CD103 intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by Tcells. Mucosal Immunol. 8, 327-339 (2014).
    • (2014) Mucosal Immunol , vol.8 , pp. 327-339
    • Scott, C.L.1
  • 40
    • 84883172356 scopus 로고    scopus 로고
    • Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-And-effacing bacterial pathogens
    • Satpathy A.T, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-And-effacing bacterial pathogens. Nat. Immunol. 14, 937-948 (2013).
    • (2013) Nat. Immunol , vol.14 , pp. 937-948
    • Satpathy, A.T.1
  • 41
    • 84857444876 scopus 로고    scopus 로고
    • Interleukin 23 production by intestinal CD103(+) CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense
    • Kinnebrew M.A, et al. Interleukin 23 production by intestinal CD103(+) CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity. 36, 276-287 (2012).
    • (2012) Immunity , vol.36 , pp. 276-287
    • Kinnebrew, M.A.1
  • 42
    • 84885447087 scopus 로고    scopus 로고
    • Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism
    • Welty N.E, Staley C, Ghilardi N, Sadowsky M.J, Igyarto B.Z, & Kaplan D.H. Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism. J. Exp. Med. 210, 2011-2024 (2013).
    • (2013) J. Exp. Med , vol.210 , pp. 2011-2024
    • Welty, N.E.1    Staley, C.2    Ghilardi, N.3    Sadowsky, M.J.4    Igyarto, B.Z.5    Kaplan, D.H.6
  • 43
    • 36349023798 scopus 로고    scopus 로고
    • Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner
    • Noguchi D, et al. Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner. Int. Immunol. 19, 1431-1440 (2007).
    • (2007) Int. Immunol , vol.19 , pp. 1431-1440
    • Noguchi, D.1
  • 44
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116, 1310-1316 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 1310-1316
    • Yen, D.1
  • 45
    • 84870886034 scopus 로고    scopus 로고
    • Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation
    • Griseri T, McKenzie B.S, Schiering C, & Powrie F. Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation. Immunity. 37, 1116-1129 (2012).
    • (2012) Immunity , vol.37 , pp. 1116-1129
    • Griseri, T.1    McKenzie, B.S.2    Schiering, C.3    Powrie, F.4
  • 46
    • 79956152607 scopus 로고    scopus 로고
    • The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
    • El-Behi M, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- And IL-23-induced production of the cytokine GM-CSF. Nat. Immunol. 12, 568-575 (2011).
    • (2011) Nat. Immunol , vol.12 , pp. 568-575
    • El-Behi, M.1
  • 47
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20, 4106-4114 (2000).
    • (2000) Mol. Cell. Biol , vol.20 , pp. 4106-4114
    • Jung, S.1
  • 48
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy K.J, Salaun L, Cahill R, Dougan G, Saunders N.J, & Powrie F. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197, 111-119 (2003).
    • (2003) J. Exp. Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.