Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10240-10245

  Weir, Eleanor C ^a   Philbrick, William M ^a   Amling, Michael ^a   Neff, Lynn A ^a   Baron, Roland ^a   Broadus, Arthur E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chondrodystrophy; developmental regulation; programmed differentiation

Indexed keywords

COLLAGEN TYPE 2; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDRODYSPLASIA; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALS; BONE DEVELOPMENT; DWARFISM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH PLATE; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, TRANSGENIC; OSTEOCHONDRODYSPLASIAS; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; POLYMERASE CHAIN REACTION; PROCOLLAGEN; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION, GENETIC;

ANIMALIA; MUS MUSCULUS;

EID: 0029811142     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10240     Document Type: Article

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