-
1
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
P.B.Chapman, A.Hauschild, C.Robert, J.B.Haanen, P.Ascierto, J.Larkin, R.Dummer, C.Garbe, A.Testori, M.Maio et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Eng J Med 2011; 364:2507; PMID:21639808; http://dx.doi.org/10.1056/NEJMoa1103782
-
(2011)
N Eng J Med
, vol.364
, pp. 2507
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
-
2
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
-
22608338
-
G.S.Falchook, G.V.Long, R.Kurzrock, K.B.Kim, T.H.Arkenau, M.P.Brown, O.Hamid, J.R.Infante, M.Millward, A.C.Pavlick et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012; 379:1893; PMID:22608338; http://dx.doi.org/10.1016/S0140-6736(12)60398-5
-
(2012)
Lancet
, vol.379
, pp. 1893
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
Kim, K.B.4
Arkenau, T.H.5
Brown, M.P.6
Hamid, O.7
Infante, J.R.8
Millward, M.9
Pavlick, A.C.10
-
3
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
K.T.Flaherty, I.Puzanov, K.B.Kim, A.Ribas, G.A.McArthur, J.A.Sosman, P.J.O'Dwyer, R.J.Lee, J.F.Grippo, K.Nolop et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Eng J Med 2010; 363:809; PMID:20818844; http://dx.doi.org/10.1056/NEJMoa1002011
-
(2010)
N Eng J Med
, vol.363
, pp. 809
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
O'Dwyer, P.J.7
Lee, R.J.8
Grippo, J.F.9
Nolop, K.10
-
4
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
J.A.Sosman, K.B.Kim, L.Schuchter, R.Gonzalez, A.C.Pavlick, J.S.Weber, G.A.McArthur, T.E.Hutson, S.J.Moschos, K.T.Flaherty et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Eng J Med 2012; 366:707; PMID:22356324; http://dx.doi.org/10.1056/NEJMoa1112302
-
(2012)
N Eng J Med
, vol.366
, pp. 707
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
Gonzalez, R.4
Pavlick, A.C.5
Weber, J.S.6
McArthur, G.A.7
Hutson, T.E.8
Moschos, S.J.9
Flaherty, K.T.10
-
5
-
-
84892805414
-
Resistance to RAF inhibitors revisited
-
24108405
-
E.Hartsough, Y.Shao, A.E.Aplin. Resistance to RAF inhibitors revisited. J Invest Dermatol 2014; 134:319; PMID:24108405; http://dx.doi.org/10.1038/jid.2013.358
-
(2014)
J Invest Dermatol
, vol.134
, pp. 319
-
-
Hartsough, E.1
Shao, Y.2
Aplin, A.E.3
-
6
-
-
84903159476
-
Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond. Nature Reviews
-
24957944
-
M.Holderfield, M.M.Deuker, F.McCormick, M.McMahon. Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond. Nature Reviews. Cancer 2014; 14:455; PMID:24957944; http://dx.doi.org/10.1038/nrc3760
-
(2014)
Cancer
, vol.14
, pp. 455
-
-
Holderfield, M.1
Deuker, M.M.2
McCormick, F.3
McMahon, M.4
-
7
-
-
84887478023
-
Tumor adaptation and resistance to RAF inhibitors
-
24202393
-
P.Lito, N.Rosen, D.B.Solit. Tumor adaptation and resistance to RAF inhibitors. Nat Med 2013; 19:1401; PMID:24202393; http://dx.doi.org/10.1038/nm.3392
-
(2013)
Nat Med
, vol.19
, pp. 1401
-
-
Lito, P.1
Rosen, N.2
Solit, D.B.3
-
8
-
-
84928174677
-
Therapy-induced tumour secretomes promote resistance and tumour progression
-
25807485
-
A.C.Obenauf, Y.Zou, A.L.Ji, S.Vanharanta, W.Shu, H.Shi, X.Kong, M.C.Bosenberg, T.Wiesner, N.Rosen et al. Therapy-induced tumour secretomes promote resistance and tumour progression. Nature 2015; 520:368; PMID:25807485; http://dx.doi.org/10.1038/nature14336
-
(2015)
Nature
, vol.520
, pp. 368
-
-
Obenauf, A.C.1
Zou, Y.2
Ji, A.L.3
Vanharanta, S.4
Shu, W.5
Shi, H.6
Kong, X.7
Bosenberg, M.C.8
Wiesner, T.9
Rosen, N.10
-
9
-
-
84897531613
-
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
-
24670642
-
C.Sun, L.Wang, S.Huang, G.J.Heynen, A.Prahallad, C.Robert, J.Haanen, C.Blank, J.Wesseling, S.M.Willems et al. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma. Nature 2014; 508:118; PMID:24670642; http://dx.doi.org/10.1038/nature13121
-
(2014)
Nature
, vol.508
, pp. 118
-
-
Sun, C.1
Wang, L.2
Huang, S.3
Heynen, G.J.4
Prahallad, A.5
Robert, C.6
Haanen, J.7
Blank, C.8
Wesseling, J.9
Willems, S.M.10
-
10
-
-
84964313375
-
Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade
-
24903021
-
Z.A.Cooper, V.R.Juneja, P.T.Sage, D.T.Frederick, A.Piris, D.Mitra, J.A.Lo, F.S.Hodi, G.J.Freeman, M.W.Bosenberg et al. Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade. Cancer Immunol Res 2014; 2:643; PMID:24903021; http://dx.doi.org/10.1158/2326-6066.CIR-13-0215
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 643
-
-
Cooper, Z.A.1
Juneja, V.R.2
Sage, P.T.3
Frederick, D.T.4
Piris, A.5
Mitra, D.6
Lo, J.A.7
Hodi, F.S.8
Freeman, G.J.9
Bosenberg, M.W.10
-
11
-
-
84874872137
-
BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
-
23307859
-
D.T.Frederick, A.Piris, A.P.Cogdill, Z.A.Cooper, C.Lezcano, C.R.Ferrone, D.Mitra, A.Boni, L.P.Newton, C.Liu et al. BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma. Clin Cancer Res 2013; 19:1225; PMID:23307859; http://dx.doi.org/10.1158/1078-0432.CCR-12-1630
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1225
-
-
Frederick, D.T.1
Piris, A.2
Cogdill, A.P.3
Cooper, Z.A.4
Lezcano, C.5
Ferrone, C.R.6
Mitra, D.7
Boni, A.8
Newton, L.P.9
Liu, C.10
-
12
-
-
84907506561
-
The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFalpha
-
25256614
-
M.P.Smith, B.Sanchez-Laorden, K.O'Brien, H.Brunton, J.Ferguson, H.Young, N.Dhomen, K.T.Flaherty, D.T.Frederick, Z.A.Cooper et al. The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFalpha. Cancer Discov 2014; 4:1214; PMID:25256614; http://dx.doi.org/10.1158/2159-8290.CD-13-1007
-
(2014)
Cancer Discov
, vol.4
, pp. 1214
-
-
Smith, M.P.1
Sanchez-Laorden, B.2
O'Brien, K.3
Brunton, H.4
Ferguson, J.5
Young, H.6
Dhomen, N.7
Flaherty, K.T.8
Frederick, D.T.9
Cooper, Z.A.10
-
13
-
-
84962320363
-
Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest
-
25358764
-
N.Acquavella, D.Clever, Z.Yu, M.Roelke-Parker, D.C.Palmer, L.Xi, H.Pflicke, Y.Ji, A.Gros, K.Hanada et al. Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest. Cancer Immunol Res 2015; 3:37; PMID:25358764; http://dx.doi.org/10.1158/2326-6066.CIR-14-0122
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 37
-
-
Acquavella, N.1
Clever, D.2
Yu, Z.3
Roelke-Parker, M.4
Palmer, D.C.5
Xi, L.6
Pflicke, H.7
Ji, Y.8
Gros, A.9
Hanada, K.10
-
14
-
-
84874595712
-
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors
-
23454771
-
D.A.Knight, S.F.Ngiow, M.Li, T.Parmenter, S.Mok, A.Cass, N.M.Haynes, K.Kinross, H.Yagita, R.C.Koya et al. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest 2013; 123:1371; PMID:23454771; http://dx.doi.org/10.1172/JCI66236
-
(2013)
J Clin Invest
, vol.123
, pp. 1371
-
-
Knight, D.A.1
Ngiow, S.F.2
Li, M.3
Parmenter, T.4
Mok, S.5
Cass, A.6
Haynes, N.M.7
Kinross, K.8
Yagita, H.9
Koya, R.C.10
-
15
-
-
84865112760
-
BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy
-
22693252
-
R.C.Koya, S.Mok, N.Otte, K.J.Blacketor, B.Comin-Anduix, P.C.Tumeh, A.Minasyan, N.A.Graham, T.G.Graeber, T.Chodon et al. BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy. Cancer Res 2012; 72:3928; PMID:22693252; http://dx.doi.org/10.1158/0008-5472.CAN-11-2837
-
(2012)
Cancer Res
, vol.72
, pp. 3928
-
-
Koya, R.C.1
Mok, S.2
Otte, N.3
Blacketor, K.J.4
Comin-Anduix, B.5
Tumeh, P.C.6
Minasyan, A.7
Graham, N.A.8
Graeber, T.G.9
Chodon, T.10
-
16
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
19197294
-
D.I.Gabrilovich, S.Nagaraj. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162; PMID:19197294; http://dx.doi.org/10.1038/nri2506
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
17
-
-
84903708438
-
CSF-1 receptor signaling in myeloid cells
-
E.R.Stanley, V.Chitu. CSF-1 receptor signaling in myeloid cells. Cold Spring Harbor Perspect Biol 2014; 6:a021857; PMID:24890514; http://dx.doi.org/10.1101/cshperspect.a021857
-
(2014)
Cold Spring Harbor Perspect Biol
, vol.6
, pp. 021857
-
-
Stanley, E.R.1
Chitu, V.2
-
18
-
-
84882637084
-
Tumor-associated macrophages: functional diversity, clinical significance, and open questions
-
S.K.Biswas, P.Allavena, A.Mantovani. Tumor-associated macrophages: functional diversity, clinical significance, and open questions. Seminars Immunopathol 2013; 35:585; PMID:23657835; http://dx.doi.org/10.1007/s00281-013-0367-7
-
(2013)
Seminars Immunopathol
, vol.35
, pp. 585
-
-
Biswas, S.K.1
Allavena, P.2
Mantovani, A.3
-
19
-
-
84928226005
-
The interaction of anticancer therapies with tumor-associated macrophages
-
25753580
-
A.Mantovani, P.Allavena. The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med 2015; 212:435; PMID:25753580; http://dx.doi.org/10.1084/jem.20150295
-
(2015)
J Exp Med
, vol.212
, pp. 435
-
-
Mantovani, A.1
Allavena, P.2
-
20
-
-
84866784798
-
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy
-
22039576
-
D.G.DeNardo, D.J.Brennan, E.Rexhepaj, B.Ruffell, S.L.Shiao, S.F.Madden, W.M.Gallagher, N.Wadhwani, S.D.Keil, S.A.Junaid et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011; 1:54; PMID:22039576; http://dx.doi.org/10.1158/2159-8274.CD-10-0028
-
(2011)
Cancer Discov
, vol.1
, pp. 54
-
-
DeNardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
Gallagher, W.M.7
Wadhwani, N.8
Keil, S.D.9
Junaid, S.A.10
-
21
-
-
84873468174
-
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
-
23221383
-
J.B.Mitchem, D.J.Brennan, B.L.Knolhoff, B.A.Belt, Y.Zhu, D.E.Sanford, L.Belaygorod, D.Carpenter, L.Collins, D.Piwnica-Worms et al. Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses. Cancer Res 2013; 73:1128; PMID:23221383; http://dx.doi.org/10.1158/0008-5472.CAN-12-2731
-
(2013)
Cancer Res
, vol.73
, pp. 1128
-
-
Mitchem, J.B.1
Brennan, D.J.2
Knolhoff, B.L.3
Belt, B.A.4
Zhu, Y.5
Sanford, D.E.6
Belaygorod, L.7
Carpenter, D.8
Collins, L.9
Piwnica-Worms, D.10
-
22
-
-
84892738557
-
Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy
-
24247719
-
S.Mok, R.C.Koya, C.Tsui, J.Xu, L.Robert, L.Wu, T.G.Graeber, B.L.West, G.Bollag, A.Ribas. Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy. Cancer Res 2014; 74:153; PMID:24247719; http://dx.doi.org/10.1158/0008-5472.CAN-13-1816
-
(2014)
Cancer Res
, vol.74
, pp. 153
-
-
Mok, S.1
Koya, R.C.2
Tsui, C.3
Xu, J.4
Robert, L.5
Wu, L.6
Graeber, T.G.7
West, B.L.8
Bollag, G.9
Ribas, A.10
-
23
-
-
84887481716
-
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
-
24056773
-
S.M.Pyonteck, L.Akkari, A.J.Schuhmacher, R.L.Bowman, L.Sevenich, D.F.Quail, O.C.Olson, M.L.Quick, J.T.Huse, V.Teijeiro et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med 2013; 19:1264; PMID:24056773; http://dx.doi.org/10.1038/nm.3337
-
(2013)
Nat Med
, vol.19
, pp. 1264
-
-
Pyonteck, S.M.1
Akkari, L.2
Schuhmacher, A.J.3
Bowman, R.L.4
Sevenich, L.5
Quail, D.F.6
Olson, O.C.7
Quick, M.L.8
Huse, J.T.9
Teijeiro, V.10
-
24
-
-
84902546715
-
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
-
24898549
-
C.H.Ries, M.A.Cannarile, S.Hoves, J.Benz, K.Wartha, V.Runza, F.Rey-Giraud, L.P.Pradel, F.Feuerhake, I.Klaman et al. Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell 2014; 25:846; PMID:24898549; http://dx.doi.org/10.1016/j.ccr.2014.05.016
-
(2014)
Cancer Cell
, vol.25
, pp. 846
-
-
Ries, C.H.1
Cannarile, M.A.2
Hoves, S.3
Benz, J.4
Wartha, K.5
Runza, V.6
Rey-Giraud, F.7
Pradel, L.P.8
Feuerhake, F.9
Klaman, I.10
-
25
-
-
84894520967
-
CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells
-
24498562
-
D.C.Strachan, B.Ruffell, Y.Oei, M.J.Bissell, L.M.Coussens, N.Pryer, D.Daniel. CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells. Oncoimmunology 2013; 2:e26968; PMID:24498562; http://dx.doi.org/10.4161/onci.26968
-
(2013)
Oncoimmunology
, vol.2
, pp. 26968
-
-
Strachan, D.C.1
Ruffell, B.2
Oei, Y.3
Bissell, M.J.4
Coussens, L.M.5
Pryer, N.6
Daniel, D.7
-
26
-
-
84962028198
-
Therapeutic peptide vaccine-induced CD8 T cells strongly modulate intratumoral macrophages required for tumor regression
-
25888578
-
T.C.van der Sluis, M.Sluijter, S.van Duikeren, B.L.West, C.J.Melief, R.Arens, S.H.van der Burg, T.van Hall. Therapeutic peptide vaccine-induced CD8 T cells strongly modulate intratumoral macrophages required for tumor regression. Cancer Immunol Res 2015; 3(9):1042-51; PMID:25888578; http://dx.doi.org/10.1158/2326-6066.
-
(2015)
Cancer Immunol Res
, vol.3
, Issue.9
, pp. 1042-1051
-
-
van der Sluis, T.C.1
Sluijter, M.2
van Duikeren, S.3
West, B.L.4
Melief, C.J.5
Arens, R.6
van der Burg, S.H.7
van Hall, T.8
-
27
-
-
84877738839
-
CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer
-
23418320
-
J.Xu, J.Escamilla, S.Mok, J.David, S.Priceman, B.West, G.Bollag, W.McBride, L.Wu. CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer. Cancer Res 2013; 73:2782; PMID:23418320; http://dx.doi.org/10.1158/0008-5472.CAN-12-3981
-
(2013)
Cancer Res
, vol.73
, pp. 2782
-
-
Xu, J.1
Escamilla, J.2
Mok, S.3
David, J.4
Priceman, S.5
West, B.6
Bollag, G.7
McBride, W.8
Wu, L.9
-
28
-
-
84907484156
-
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models
-
25082815
-
Y.Zhu, B.L.Knolhoff, M.A.Meyer, T.M.Nywening, B.L.West, J.Luo, A.Wang-Gillam, S.P.Goedegebuure, D.C.Linehan, D.G.DeNardo. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res 2014; 74:5057; PMID:25082815; http://dx.doi.org/10.1158/0008-5472.CAN-13-3723
-
(2014)
Cancer Res
, vol.74
, pp. 5057
-
-
Zhu, Y.1
Knolhoff, B.L.2
Meyer, M.A.3
Nywening, T.M.4
West, B.L.5
Luo, J.6
Wang-Gillam, A.7
Goedegebuure, S.P.8
Linehan, D.C.9
DeNardo, D.G.10
-
29
-
-
84903464388
-
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNgamma
-
24736544
-
P.C.Ho, K.M.Meeth, Y.C.Tsui, B.Srivastava, M.W.Bosenberg, S.M.Kaech. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNgamma. Cancer Res 2014; 74:3205; PMID:24736544; http://dx.doi.org/10.1158/0008-5472.CAN-13-3461
-
(2014)
Cancer Res
, vol.74
, pp. 3205
-
-
Ho, P.C.1
Meeth, K.M.2
Tsui, Y.C.3
Srivastava, B.4
Bosenberg, M.W.5
Kaech, S.M.6
-
30
-
-
84991510642
-
BRAF inhibition alleviates immune suppression in murine autochthonous melanoma
-
25183499
-
S.M.Steinberg, P.Zhang, B.T.Malik, A.Boni, T.B.Shabaneh, K.T.Byrne, D.W.Mullins, C.E.Brinckerhoff, M.S.Ernstoff, M.W.Bosenberg, M.J.Turk. BRAF inhibition alleviates immune suppression in murine autochthonous melanoma. Cancer Immunol Res 2014; 2:1044; PMID:25183499; http://dx.doi.org/10.1158/2326-6066.CIR-14-0074
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 1044
-
-
Steinberg, S.M.1
Zhang, P.2
Malik, B.T.3
Boni, A.4
Shabaneh, T.B.5
Byrne, K.T.6
Mullins, D.W.7
Brinckerhoff, C.E.8
Ernstoff, M.S.9
Bosenberg, M.W.10
Turk, M.J.11
-
31
-
-
0036839143
-
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
A.Mantovani, S.Sozzani, M.Locati, P.Allavena, A.Sica. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends in Immunol 2002; 23:549; PMID:12401408; http://dx.doi.org/10.1016/S1471-4906(02)02302-5
-
(2002)
Trends in Immunol
, vol.23
, pp. 549
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
32
-
-
84925607772
-
Adoptive cellular therapy: a race to the finish line
-
C.H.June, S.R.Riddell, T.N.Schumacher. Adoptive cellular therapy: a race to the finish line. Science Trans Med 2015; 7:280ps7; PMID:25810311; http://dx.doi.org/10.1126/scitranslmed.aaa3643
-
(2015)
Science Trans Med
, vol.7
, pp. 2807
-
-
June, C.H.1
Riddell, S.R.2
Schumacher, T.N.3
-
33
-
-
84893965118
-
Immune modulation in cancer with antibodies
-
D.B.Page, M.A.Postow, M.K.Callahan, J.P.Allison, J.D.Wolchok. Immune modulation in cancer with antibodies. Annual Rev Med 2014; 65:185; PMID:24188664; http://dx.doi.org/10.1146/annurev-med-092012-112807
-
(2014)
Annual Rev Med
, vol.65
, pp. 185
-
-
Page, D.B.1
Postow, M.A.2
Callahan, M.K.3
Allison, J.P.4
Wolchok, J.D.5
-
34
-
-
14844288910
-
Lymphoid progenitors and primary routes to becoming cells of the immune system
-
15766667
-
R.Pelayo, R.Welner, S.S.Perry, J.Huang, Y.Baba, T.Yokota, P.W.Kincade. Lymphoid progenitors and primary routes to becoming cells of the immune system. Curr Opin Immunol 2005; 17:100; PMID:15766667; http://dx.doi.org/10.1016/j.coi.2005.01.012
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 100
-
-
Pelayo, R.1
Welner, R.2
Perry, S.S.3
Huang, J.4
Baba, Y.5
Yokota, T.6
Kincade, P.W.7
-
35
-
-
84861888837
-
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells
-
22427351
-
M.Terme, E.Ullrich, L.Aymeric, K.Meinhardt, J.D.Coudert, M.Desbois, F.Ghiringhelli, S.Viaud, B.Ryffel, H.Yagita et al. Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res 2012; 72:2757; PMID:22427351; http://dx.doi.org/10.1158/0008-5472.CAN-11-3379
-
(2012)
Cancer Res
, vol.72
, pp. 2757
-
-
Terme, M.1
Ullrich, E.2
Aymeric, L.3
Meinhardt, K.4
Coudert, J.D.5
Desbois, M.6
Ghiringhelli, F.7
Viaud, S.8
Ryffel, B.9
Yagita, H.10
-
36
-
-
84902596389
-
Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor
-
24416731
-
M.K.Callahan, G.Masters, C.A.Pratilas, C.Ariyan, J.Katz, S.Kitano, V.Russell, R.A.Gordon, S.Vyas, J.Yuan et al. Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor. Cancer Immunol Res 2014; 2:70; PMID:24416731; http://dx.doi.org/10.1158/2326-6066.CIR-13-0160
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 70
-
-
Callahan, M.K.1
Masters, G.2
Pratilas, C.A.3
Ariyan, C.4
Katz, J.5
Kitano, S.6
Russell, V.7
Gordon, R.A.8
Vyas, S.9
Yuan, J.10
-
37
-
-
84918591464
-
Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma
-
25351955
-
L.Ferrari de Andrade, S.F.Ngiow, K.Stannard, S.Rusakiewicz, M.Kalimutho, K.K.Khanna, S.K.Tey, K.Takeda, L.Zitvogel, L.Martinet et al. Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Res 2014; 74:7298; PMID:25351955; http://dx.doi.org/10.1158/0008-5472.CAN-14-1339
-
(2014)
Cancer Res
, vol.74
, pp. 7298
-
-
Ferrari de Andrade, L.1
Ngiow, S.F.2
Stannard, K.3
Rusakiewicz, S.4
Kalimutho, M.5
Khanna, K.K.6
Tey, S.K.7
Takeda, K.8
Zitvogel, L.9
Martinet, L.10
-
38
-
-
84930194314
-
Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition
-
25939769
-
S.Mok, J.Tsoi, R.C.Koya, S.Hu-Lieskovan, B.L.West, G.Bollag, T.G.Graeber, A.Ribas. Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition. BMC Cancer 2015; 15:356; PMID:25939769; http://dx.doi.org/10.1186/s12885-015-1377-8
-
(2015)
BMC Cancer
, vol.15
, pp. 356
-
-
Mok, S.1
Tsoi, J.2
Koya, R.C.3
Hu-Lieskovan, S.4
West, B.L.5
Bollag, G.6
Graeber, T.G.7
Ribas, A.8
-
39
-
-
84859128199
-
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
J.M.Taube, R.A.Anders, G.D.Young, H.Xu, R.Sharma, T.L.McMiller, S.Chen, A.P.Klein, D.M.Pardoll, S.L.Topalian, L.Chen. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science Translational Med 2012; 4:127ra37; PMID:22461641; http://dx.doi.org/10.1126/scitranslmed.3003689
-
(2012)
Science Translational Med
, vol.4
, pp. 12737
-
-
Taube, J.M.1
Anders, R.A.2
Young, G.D.3
Xu, H.4
Sharma, R.5
McMiller, T.L.6
Chen, S.7
Klein, A.P.8
Pardoll, D.M.9
Topalian, S.L.10
Chen, L.11
-
40
-
-
84941797037
-
Classifying Cancers Based on T-cell Infiltration and PD-L1
-
25977340
-
M.W.Teng, S.F.Ngiow, A.Ribas, M.J.Smyth. Classifying Cancers Based on T-cell Infiltration and PD-L1. Cancer Research 2015; 75:2139; PMID:25977340; http://dx.doi.org/10.1158/0008-5472.CAN-15-0255
-
(2015)
Cancer Research
, vol.75
, pp. 2139
-
-
Teng, M.W.1
Ngiow, S.F.2
Ribas, A.3
Smyth, M.J.4
-
41
-
-
65649147543
-
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma
-
19282848
-
D.Dankort, D.P.Curley, R.A.Cartlidge, B.Nelson, A.N.Karnezis, W.E.Damsky, Jr, M.J.You, R.A.DePinho, M.McMahon, M.Bosenberg. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nature Genetics 2009; 41:544; PMID:19282848; http://dx.doi.org/10.1038/ng.356
-
(2009)
Nature Genetics
, vol.41
, pp. 544
-
-
Dankort, D.1
Curley, D.P.2
Cartlidge, R.A.3
Nelson, B.4
Karnezis, A.N.5
Damsky, W.E.6
You, M.J.7
DePinho, R.A.8
McMahon, M.9
Bosenberg, M.10
-
42
-
-
42949149240
-
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
-
18287029
-
J.Tsai, J.T.Lee, W.Wang, J.Zhang, H.Cho, S.Mamo, R.Bremer, S.Gillette, J.Kong, N.K.Haass et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci USA 2008; 105:3041; PMID:18287029; http://dx.doi.org/10.1073/pnas.0711741105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3041
-
-
Tsai, J.1
Lee, J.T.2
Wang, W.3
Zhang, J.4
Cho, H.5
Mamo, S.6
Bremer, R.7
Gillette, S.8
Kong, J.9
Haass, N.K.10
-
43
-
-
84938369565
-
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor
-
W.D.Tap, Z.A.Wainberg, S.P.Anthony, P.N.Ibrahim, C.Zhang, J.H.Healey, B.Chmielowski, A.P.Staddon, A.L.Cohn, G.I.Shapiro et al. Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor. N Eng J Med 2015; 373:428; PMID:26222558; http://dx.doi.org/10.1056/NEJMoa1411366
-
(2015)
N Eng J Med
, vol.373
, pp. 428
-
-
Tap, W.D.1
Wainberg, Z.A.2
Anthony, S.P.3
Ibrahim, P.N.4
Zhang, C.5
Healey, J.H.6
Chmielowski, B.7
Staddon, A.P.8
Cohn, A.L.9
Shapiro, G.I.10
-
44
-
-
83455171909
-
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas
-
22172720
-
W.E.Damsky, D.P.Curley, M.Santhanakrishnan, L.E.Rosenbaum, J.T.Platt, B.E.Gould Rothberg, M.M.Taketo, D.Dankort, D.L.Rimm, M.McMahon, M.Bosenberg. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell 2011; 20:741; PMID:22172720; http://dx.doi.org/10.1016/j.ccr.2011.10.030
-
(2011)
Cancer Cell
, vol.20
, pp. 741
-
-
Damsky, W.E.1
Curley, D.P.2
Santhanakrishnan, M.3
Rosenbaum, L.E.4
Platt, J.T.5
Gould Rothberg, B.E.6
Taketo, M.M.7
Dankort, D.8
Rimm, D.L.9
McMahon, M.10
Bosenberg, M.11
-
45
-
-
79956103042
-
Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors
-
21430066
-
S.F.Ngiow, B.von Scheidt, H.Akiba, H.Yagita, M.W.L.Teng, M.J.Smyth. Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors. Cancer Res 2011; 71:3540; PMID:21430066; http://dx.doi.org/10.1158/0008-5472.CAN-11-0096
-
(2011)
Cancer Res
, vol.71
, pp. 3540
-
-
Ngiow, S.F.1
von Scheidt, B.2
Akiba, H.3
Yagita, H.4
Teng, M.W.L.5
Smyth, M.J.6
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