메뉴 건너뛰기




Volumn 5, Issue 3, 2016, Pages

Co-inhibition of colony stimulating factor-1 receptor and BRAF oncogene in mouse models of BRAFV600Emelanoma

Author keywords

BRAF inhibitor; BRAFV600E; CSF1R; M2 macrophage; melanoma; PLX3397; PLX4720; tumor

Indexed keywords

B RAF KINASE INHIBITOR; COLONY STIMULATING FACTOR RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN10; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; PLX 3397; PROTEIN TYROSINE KINASE INHIBITOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VEMURAFENIB;

EID: 84961619711     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1089381     Document Type: Article
Times cited : (33)

References (45)
  • 2
    • 84861083983 scopus 로고    scopus 로고
    • Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
    • 22608338
    • G.S.Falchook, G.V.Long, R.Kurzrock, K.B.Kim, T.H.Arkenau, M.P.Brown, O.Hamid, J.R.Infante, M.Millward, A.C.Pavlick et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012; 379:1893; PMID:22608338; http://dx.doi.org/10.1016/S0140-6736(12)60398-5
    • (2012) Lancet , vol.379 , pp. 1893
    • Falchook, G.S.1    Long, G.V.2    Kurzrock, R.3    Kim, K.B.4    Arkenau, T.H.5    Brown, M.P.6    Hamid, O.7    Infante, J.R.8    Millward, M.9    Pavlick, A.C.10
  • 5
    • 84892805414 scopus 로고    scopus 로고
    • Resistance to RAF inhibitors revisited
    • 24108405
    • E.Hartsough, Y.Shao, A.E.Aplin. Resistance to RAF inhibitors revisited. J Invest Dermatol 2014; 134:319; PMID:24108405; http://dx.doi.org/10.1038/jid.2013.358
    • (2014) J Invest Dermatol , vol.134 , pp. 319
    • Hartsough, E.1    Shao, Y.2    Aplin, A.E.3
  • 6
    • 84903159476 scopus 로고    scopus 로고
    • Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond. Nature Reviews
    • 24957944
    • M.Holderfield, M.M.Deuker, F.McCormick, M.McMahon. Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond. Nature Reviews. Cancer 2014; 14:455; PMID:24957944; http://dx.doi.org/10.1038/nrc3760
    • (2014) Cancer , vol.14 , pp. 455
    • Holderfield, M.1    Deuker, M.M.2    McCormick, F.3    McMahon, M.4
  • 7
    • 84887478023 scopus 로고    scopus 로고
    • Tumor adaptation and resistance to RAF inhibitors
    • 24202393
    • P.Lito, N.Rosen, D.B.Solit. Tumor adaptation and resistance to RAF inhibitors. Nat Med 2013; 19:1401; PMID:24202393; http://dx.doi.org/10.1038/nm.3392
    • (2013) Nat Med , vol.19 , pp. 1401
    • Lito, P.1    Rosen, N.2    Solit, D.B.3
  • 11
    • 84874872137 scopus 로고    scopus 로고
    • BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
    • 23307859
    • D.T.Frederick, A.Piris, A.P.Cogdill, Z.A.Cooper, C.Lezcano, C.R.Ferrone, D.Mitra, A.Boni, L.P.Newton, C.Liu et al. BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma. Clin Cancer Res 2013; 19:1225; PMID:23307859; http://dx.doi.org/10.1158/1078-0432.CCR-12-1630
    • (2013) Clin Cancer Res , vol.19 , pp. 1225
    • Frederick, D.T.1    Piris, A.2    Cogdill, A.P.3    Cooper, Z.A.4    Lezcano, C.5    Ferrone, C.R.6    Mitra, D.7    Boni, A.8    Newton, L.P.9    Liu, C.10
  • 16
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 19197294
    • D.I.Gabrilovich, S.Nagaraj. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162; PMID:19197294; http://dx.doi.org/10.1038/nri2506
    • (2009) Nat Rev Immunol , vol.9 , pp. 162
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 17
    • 84903708438 scopus 로고    scopus 로고
    • CSF-1 receptor signaling in myeloid cells
    • E.R.Stanley, V.Chitu. CSF-1 receptor signaling in myeloid cells. Cold Spring Harbor Perspect Biol 2014; 6:a021857; PMID:24890514; http://dx.doi.org/10.1101/cshperspect.a021857
    • (2014) Cold Spring Harbor Perspect Biol , vol.6 , pp. 021857
    • Stanley, E.R.1    Chitu, V.2
  • 18
    • 84882637084 scopus 로고    scopus 로고
    • Tumor-associated macrophages: functional diversity, clinical significance, and open questions
    • S.K.Biswas, P.Allavena, A.Mantovani. Tumor-associated macrophages: functional diversity, clinical significance, and open questions. Seminars Immunopathol 2013; 35:585; PMID:23657835; http://dx.doi.org/10.1007/s00281-013-0367-7
    • (2013) Seminars Immunopathol , vol.35 , pp. 585
    • Biswas, S.K.1    Allavena, P.2    Mantovani, A.3
  • 19
    • 84928226005 scopus 로고    scopus 로고
    • The interaction of anticancer therapies with tumor-associated macrophages
    • 25753580
    • A.Mantovani, P.Allavena. The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med 2015; 212:435; PMID:25753580; http://dx.doi.org/10.1084/jem.20150295
    • (2015) J Exp Med , vol.212 , pp. 435
    • Mantovani, A.1    Allavena, P.2
  • 21
    • 84873468174 scopus 로고    scopus 로고
    • Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses
    • 23221383
    • J.B.Mitchem, D.J.Brennan, B.L.Knolhoff, B.A.Belt, Y.Zhu, D.E.Sanford, L.Belaygorod, D.Carpenter, L.Collins, D.Piwnica-Worms et al. Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses. Cancer Res 2013; 73:1128; PMID:23221383; http://dx.doi.org/10.1158/0008-5472.CAN-12-2731
    • (2013) Cancer Res , vol.73 , pp. 1128
    • Mitchem, J.B.1    Brennan, D.J.2    Knolhoff, B.L.3    Belt, B.A.4    Zhu, Y.5    Sanford, D.E.6    Belaygorod, L.7    Carpenter, D.8    Collins, L.9    Piwnica-Worms, D.10
  • 22
    • 84892738557 scopus 로고    scopus 로고
    • Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy
    • 24247719
    • S.Mok, R.C.Koya, C.Tsui, J.Xu, L.Robert, L.Wu, T.G.Graeber, B.L.West, G.Bollag, A.Ribas. Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy. Cancer Res 2014; 74:153; PMID:24247719; http://dx.doi.org/10.1158/0008-5472.CAN-13-1816
    • (2014) Cancer Res , vol.74 , pp. 153
    • Mok, S.1    Koya, R.C.2    Tsui, C.3    Xu, J.4    Robert, L.5    Wu, L.6    Graeber, T.G.7    West, B.L.8    Bollag, G.9    Ribas, A.10
  • 25
    • 84894520967 scopus 로고    scopus 로고
    • CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells
    • 24498562
    • D.C.Strachan, B.Ruffell, Y.Oei, M.J.Bissell, L.M.Coussens, N.Pryer, D.Daniel. CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells. Oncoimmunology 2013; 2:e26968; PMID:24498562; http://dx.doi.org/10.4161/onci.26968
    • (2013) Oncoimmunology , vol.2 , pp. 26968
    • Strachan, D.C.1    Ruffell, B.2    Oei, Y.3    Bissell, M.J.4    Coussens, L.M.5    Pryer, N.6    Daniel, D.7
  • 26
    • 84962028198 scopus 로고    scopus 로고
    • Therapeutic peptide vaccine-induced CD8 T cells strongly modulate intratumoral macrophages required for tumor regression
    • 25888578
    • T.C.van der Sluis, M.Sluijter, S.van Duikeren, B.L.West, C.J.Melief, R.Arens, S.H.van der Burg, T.van Hall. Therapeutic peptide vaccine-induced CD8 T cells strongly modulate intratumoral macrophages required for tumor regression. Cancer Immunol Res 2015; 3(9):1042-51; PMID:25888578; http://dx.doi.org/10.1158/2326-6066.
    • (2015) Cancer Immunol Res , vol.3 , Issue.9 , pp. 1042-1051
    • van der Sluis, T.C.1    Sluijter, M.2    van Duikeren, S.3    West, B.L.4    Melief, C.J.5    Arens, R.6    van der Burg, S.H.7    van Hall, T.8
  • 27
    • 84877738839 scopus 로고    scopus 로고
    • CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer
    • 23418320
    • J.Xu, J.Escamilla, S.Mok, J.David, S.Priceman, B.West, G.Bollag, W.McBride, L.Wu. CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer. Cancer Res 2013; 73:2782; PMID:23418320; http://dx.doi.org/10.1158/0008-5472.CAN-12-3981
    • (2013) Cancer Res , vol.73 , pp. 2782
    • Xu, J.1    Escamilla, J.2    Mok, S.3    David, J.4    Priceman, S.5    West, B.6    Bollag, G.7    McBride, W.8    Wu, L.9
  • 28
    • 84907484156 scopus 로고    scopus 로고
    • CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models
    • 25082815
    • Y.Zhu, B.L.Knolhoff, M.A.Meyer, T.M.Nywening, B.L.West, J.Luo, A.Wang-Gillam, S.P.Goedegebuure, D.C.Linehan, D.G.DeNardo. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res 2014; 74:5057; PMID:25082815; http://dx.doi.org/10.1158/0008-5472.CAN-13-3723
    • (2014) Cancer Res , vol.74 , pp. 5057
    • Zhu, Y.1    Knolhoff, B.L.2    Meyer, M.A.3    Nywening, T.M.4    West, B.L.5    Luo, J.6    Wang-Gillam, A.7    Goedegebuure, S.P.8    Linehan, D.C.9    DeNardo, D.G.10
  • 29
    • 84903464388 scopus 로고    scopus 로고
    • Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNgamma
    • 24736544
    • P.C.Ho, K.M.Meeth, Y.C.Tsui, B.Srivastava, M.W.Bosenberg, S.M.Kaech. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNgamma. Cancer Res 2014; 74:3205; PMID:24736544; http://dx.doi.org/10.1158/0008-5472.CAN-13-3461
    • (2014) Cancer Res , vol.74 , pp. 3205
    • Ho, P.C.1    Meeth, K.M.2    Tsui, Y.C.3    Srivastava, B.4    Bosenberg, M.W.5    Kaech, S.M.6
  • 31
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • A.Mantovani, S.Sozzani, M.Locati, P.Allavena, A.Sica. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends in Immunol 2002; 23:549; PMID:12401408; http://dx.doi.org/10.1016/S1471-4906(02)02302-5
    • (2002) Trends in Immunol , vol.23 , pp. 549
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 32
    • 84925607772 scopus 로고    scopus 로고
    • Adoptive cellular therapy: a race to the finish line
    • C.H.June, S.R.Riddell, T.N.Schumacher. Adoptive cellular therapy: a race to the finish line. Science Trans Med 2015; 7:280ps7; PMID:25810311; http://dx.doi.org/10.1126/scitranslmed.aaa3643
    • (2015) Science Trans Med , vol.7 , pp. 2807
    • June, C.H.1    Riddell, S.R.2    Schumacher, T.N.3
  • 34
    • 14844288910 scopus 로고    scopus 로고
    • Lymphoid progenitors and primary routes to becoming cells of the immune system
    • 15766667
    • R.Pelayo, R.Welner, S.S.Perry, J.Huang, Y.Baba, T.Yokota, P.W.Kincade. Lymphoid progenitors and primary routes to becoming cells of the immune system. Curr Opin Immunol 2005; 17:100; PMID:15766667; http://dx.doi.org/10.1016/j.coi.2005.01.012
    • (2005) Curr Opin Immunol , vol.17 , pp. 100
    • Pelayo, R.1    Welner, R.2    Perry, S.S.3    Huang, J.4    Baba, Y.5    Yokota, T.6    Kincade, P.W.7
  • 38
    • 84930194314 scopus 로고    scopus 로고
    • Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition
    • 25939769
    • S.Mok, J.Tsoi, R.C.Koya, S.Hu-Lieskovan, B.L.West, G.Bollag, T.G.Graeber, A.Ribas. Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition. BMC Cancer 2015; 15:356; PMID:25939769; http://dx.doi.org/10.1186/s12885-015-1377-8
    • (2015) BMC Cancer , vol.15 , pp. 356
    • Mok, S.1    Tsoi, J.2    Koya, R.C.3    Hu-Lieskovan, S.4    West, B.L.5    Bollag, G.6    Graeber, T.G.7    Ribas, A.8
  • 39
  • 40
    • 84941797037 scopus 로고    scopus 로고
    • Classifying Cancers Based on T-cell Infiltration and PD-L1
    • 25977340
    • M.W.Teng, S.F.Ngiow, A.Ribas, M.J.Smyth. Classifying Cancers Based on T-cell Infiltration and PD-L1. Cancer Research 2015; 75:2139; PMID:25977340; http://dx.doi.org/10.1158/0008-5472.CAN-15-0255
    • (2015) Cancer Research , vol.75 , pp. 2139
    • Teng, M.W.1    Ngiow, S.F.2    Ribas, A.3    Smyth, M.J.4
  • 45
    • 79956103042 scopus 로고    scopus 로고
    • Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors
    • 21430066
    • S.F.Ngiow, B.von Scheidt, H.Akiba, H.Yagita, M.W.L.Teng, M.J.Smyth. Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors. Cancer Res 2011; 71:3540; PMID:21430066; http://dx.doi.org/10.1158/0008-5472.CAN-11-0096
    • (2011) Cancer Res , vol.71 , pp. 3540
    • Ngiow, S.F.1    von Scheidt, B.2    Akiba, H.3    Yagita, H.4    Teng, M.W.L.5    Smyth, M.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.