-
1
-
-
84931042800
-
Inside the first pig biobank
-
Abbott A., (2015). Inside the first pig biobank. Nature 519, 397-98.
-
(2015)
Nature
, vol.519
, pp. 397-398
-
-
Abbott, A.1
-
2
-
-
77954538843
-
Transgenic pigs as models for translational biomedical research
-
Aigner B., Renner S., Kessler B., Klymiuk N., Kurome M., Wunsch A., Wolf E., (2010). Transgenic pigs as models for translational biomedical research. J Mol Med (Berl) 88, 653-64.
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 653-664
-
-
Aigner, B.1
Renner, S.2
Kessler, B.3
Klymiuk, N.4
Kurome, M.5
Wunsch, A.6
Wolf, E.7
-
3
-
-
84884275014
-
STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies
-
Bolon B., Garman R. H., Pardo I. D., Jensen K., Sills R. C., Roulois A., Radovsky A., Bradley A., Andrews-Jones L., Butt M., Gumprecht L., (2013). STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies. Toxicol Pathol 41, 1028-48.
-
(2013)
Toxicol Pathol
, vol.41
, pp. 1028-1048
-
-
Bolon, B.1
Garman, R.H.2
Pardo, I.D.3
Jensen, K.4
Sills, R.C.5
Roulois, A.6
Radovsky, A.7
Bradley, A.8
Andrews-Jones, L.9
Butt, M.10
Gumprecht, L.11
-
4
-
-
0037350372
-
Recommended tissue list for histopathologic examination in repeat-dose toxicity and carcinogenicity studies: A proposal of the Society of Toxicologic Pathology (STP)
-
Bregman C. L., Adler R. R., Morton D. G., Regan K. S., Yano B. L., (2003). Recommended tissue list for histopathologic examination in repeat-dose toxicity and carcinogenicity studies: a proposal of the Society of Toxicologic Pathology (STP). Toxicol Pathol 31, 252-53.
-
(2003)
Toxicol Pathol
, vol.31
, pp. 252-253
-
-
Bregman, C.L.1
Adler, R.R.2
Morton, D.G.3
Regan, K.S.4
Yano, B.L.5
-
5
-
-
79952804250
-
Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry
-
Goodwin R. J., Pitt A. R., Harrison D., Weidt S. K., Langridge-Smith P. R., Barrett M. P., Logan Mackay C., (2011). Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom 25, 969-72.
-
(2011)
Rapid Commun Mass Spectrom
, vol.25
, pp. 969-972
-
-
Goodwin, R.J.1
Pitt, A.R.2
Harrison, D.3
Weidt, S.K.4
Langridge-Smith, P.R.5
Barrett, M.P.6
Logan Mackay, C.7
-
6
-
-
84926321082
-
Current progress of genetically engineered pig models for biomedical research
-
Gun G., Kues W. A., (2014). Current progress of genetically engineered pig models for biomedical research. Biores Open Access 3, 255-64.
-
(2014)
Biores Open Access
, vol.3
, pp. 255-264
-
-
Gun, G.1
Kues, W.A.2
-
7
-
-
84985280160
-
The efficiency of systematic sampling in stereology and its prediction
-
Gundersen H. J. G., Jensen E. B., (1987). The efficiency of systematic sampling in stereology and its prediction. J Microsc 147, 229-63.
-
(1987)
J Microsc
, vol.147
, pp. 229-263
-
-
Gundersen, H.J.G.1
Jensen, E.B.2
-
8
-
-
84884045098
-
-
Stereological principles and sampling procedures for toxicologic pathologists. In (eds.), 3rd ed. London: Academic Press
-
Gundersen H. J. G., Mirabile R., Brown D., Boyce R. W., (2013). Stereological principles and sampling procedures for toxicologic pathologists. In Haschek and Rousseaux's Handbook of Toxicologic Pathology (Haschek W., Rousseaux C., Wallig M.,. eds.), 3rd ed., 215-86. London: Academic Press.
-
(2013)
Haschek and Rousseaux's Handbook of Toxicologic Pathology
, pp. 215-286
-
-
Gundersen, H.J.G.1
Mirabile, R.2
Brown, D.3
Boyce, R.W.4
Haschek, W.5
Rousseaux, C.6
Wallig, M.7
-
9
-
-
20944442212
-
STP position paper: Best practice guideline for the routine pathology evaluation of the immune system
-
discussion 408
-
Haley P., Perry R., Ennulat D., Frame S., Johnson C., Lapointe J. M., Nyska A., Snyder P., Walker D., Walter G., (2005). STP position paper: Best practice guideline for the routine pathology evaluation of the immune system. Toxicol Pathol 33, 404-7,. discussion 408.
-
(2005)
Toxicol Pathol
, vol.33
, pp. 404-407
-
-
Haley, P.1
Perry, R.2
Ennulat, D.3
Frame, S.4
Johnson, C.5
Lapointe, J.M.6
Nyska, A.7
Snyder, P.8
Walker, D.9
Walter, G.10
-
10
-
-
0019819831
-
Postembedding immunohistochemical demonstration of antigen in experimental polyarthritis using plastic embedded whole joints
-
Hermanns W., Liebig K., Schulz L. C., (1981). Postembedding immunohistochemical demonstration of antigen in experimental polyarthritis using plastic embedded whole joints. Histochemistry 73, 439-46.
-
(1981)
Histochemistry
, vol.73
, pp. 439-446
-
-
Hermanns, W.1
Liebig, K.2
Schulz, L.C.3
-
12
-
-
84857569876
-
Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses
-
Kemter E., Lieke T., Kessler B., Kurome M., Wuensch A., Summerfield A., Ayares D., Nagashima H., Baars W., Schwinzer R., Wolf E., (2012). Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation 19, 40-51.
-
(2012)
Xenotransplantation
, vol.19
, pp. 40-51
-
-
Kemter, E.1
Lieke, T.2
Kessler, B.3
Kurome, M.4
Wuensch, A.5
Summerfield, A.6
Ayares, D.7
Nagashima, H.8
Baars, W.9
Schwinzer, R.10
Wolf, E.11
-
13
-
-
4143108176
-
Revised guides for organ sampling and trimming in rats and mice - Part 2. A joint publication of the RITA and NACAD groups
-
Kittel B., Ruehl-Fehlert C., Morawietz G., Klapwijk J., Elwell M. R., Lenz B., O'Sullivan M. G., Roth D. R., Wadsworth P. F., Group R., Group N., (2004). Revised guides for organ sampling and trimming in rats and mice-Part 2. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol 55, 413-31.
-
(2004)
Exp Toxicol Pathol
, vol.55
, pp. 413-431
-
-
Kittel, B.1
Ruehl-Fehlert, C.2
Morawietz, G.3
Klapwijk, J.4
Elwell, M.R.5
Lenz, B.6
O'Sullivan, M.G.7
Roth, D.R.8
Wadsworth, P.F.9
Group, R.10
Group, N.11
-
14
-
-
76649115593
-
Genetic modification of pigs as organ donors for xenotransplantation
-
Klymiuk N., Aigner B., Brem G., Wolf E., (2010). Genetic modification of pigs as organ donors for xenotransplantation. Mol Reprod Dev 77, 209-21.
-
(2010)
Mol Reprod Dev
, vol.77
, pp. 209-221
-
-
Klymiuk, N.1
Aigner, B.2
Brem, G.3
Wolf, E.4
-
15
-
-
84885723361
-
Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle
-
Klymiuk N., Blutke A., Graf A., Krause S., Burkhardt K., Wuensch A., Krebs S., Kessler B., Zakhartchenko V., Kurome M., Kemter E., Nagashima H., Schoser B., Herbach N., Blum H., Wanke R., Aartsma-Rus A., Thirion C., Lochmuller H., Walter M. C., Wolf E., (2013). Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. Hum Mol Genet 22, 4368-82.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4368-4382
-
-
Klymiuk, N.1
Blutke, A.2
Graf, A.3
Krause, S.4
Burkhardt, K.5
Wuensch, A.6
Krebs, S.7
Kessler, B.8
Zakhartchenko, V.9
Kurome, M.10
Kemter, E.11
Nagashima, H.12
Schoser, B.13
Herbach, N.14
Blum, H.15
Wanke, R.16
Aartsma-Rus, A.17
Thirion, C.18
Lochmuller, H.19
Walter, M.C.20
Wolf, E.21
more..
-
16
-
-
84857730442
-
First inducible transgene expression in porcine large animal models
-
Klymiuk N., Bocker W., Schonitzer V., Bahr A., Radic T., Frohlich T., Wunsch A., Kessler B., Kurome M., Schilling E., Herbach N., Wanke R., Nagashima H., Mutschler W., Arnold G. J., Schwinzer R., Schieker M., Wolf E., (2012a). First inducible transgene expression in porcine large animal models. FASEB J 26, 1086-99.
-
(2012)
FASEB J
, vol.26
, pp. 1086-1099
-
-
Klymiuk, N.1
Bocker, W.2
Schonitzer, V.3
Bahr, A.4
Radic, T.5
Frohlich, T.6
Wunsch, A.7
Kessler, B.8
Kurome, M.9
Schilling, E.10
Herbach, N.11
Wanke, R.12
Nagashima, H.13
Mutschler, W.14
Arnold, G.J.15
Schwinzer, R.16
Schieker, M.17
Wolf, E.18
-
17
-
-
84862577098
-
Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis
-
Klymiuk N., Mundhenk L., Kraehe K., Wuensch A., Plog S., Emrich D., Langenmayer M. C., Stehr M., Holzinger A., Kroner C., Richter A., Kessler B., Kurome M., Eddicks M., Nagashima H., Heinritzi K., Gruber A. D., Wolf E., (2012b). Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis. J Mol Med (Berl) 90, 597-608.
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 597-608
-
-
Klymiuk, N.1
Mundhenk, L.2
Kraehe, K.3
Wuensch, A.4
Plog, S.5
Emrich, D.6
Langenmayer, M.C.7
Stehr, M.8
Holzinger, A.9
Kroner, C.10
Richter, A.11
Kessler, B.12
Kurome, M.13
Eddicks, M.14
Nagashima, H.15
Heinritzi, K.16
Gruber, A.D.17
Wolf, E.18
-
18
-
-
84961622921
-
Tailored pig models for preclinical efficacy and safety testing of targeted therapies
-
Published electronically October 27, doi:0192623315609688
-
Klymiuk N., Seeliger F., Bohlooly Y. M., Blutke A., Rudmann D. G., Wolf E, Tailored pig models for preclinical efficacy and safety testing of targeted therapies. Toxicol Pathol. Published electronically October 27, 2015. doi:0192623315609688.
-
(2015)
Toxicol Pathol
-
-
Klymiuk, N.1
Seeliger, F.2
Bohlooly, Y.M.3
Blutke, A.4
Rudmann, D.G.5
Wolf, E.6
-
19
-
-
84861898204
-
Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice
-
Klymiuk N., van Buerck L., Bahr A., Offers M., Kessler B., Wuensch A., Kurome M., Thormann M., Lochner K., Nagashima H., Herbach N., Wanke R., Seissler J., Wolf E., (2012c). Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice. Diabetes 61, 1527-32.
-
(2012)
Diabetes
, vol.61
, pp. 1527-1532
-
-
Klymiuk, N.1
Van Buerck, L.2
Bahr, A.3
Offers, M.4
Kessler, B.5
Wuensch, A.6
Kurome, M.7
Thormann, M.8
Lochner, K.9
Nagashima, H.10
Herbach, N.11
Wanke, R.12
Seissler, J.13
Wolf, E.14
-
20
-
-
84954593118
-
Nuclear transfer and transgenesis in the pig
-
Kurome M., Kessler B., Wuensch A., Nagashima H., Wolf E., (2015). Nuclear transfer and transgenesis in the pig. Methods Mol Biol 1222, 37-59.
-
(2015)
Methods Mol Biol
, vol.1222
, pp. 37-59
-
-
Kurome, M.1
Kessler, B.2
Wuensch, A.3
Nagashima, H.4
Wolf, E.5
-
21
-
-
33847068799
-
Advances in swine biomedical model genomics
-
Lunney J. K., (2007). Advances in swine biomedical model genomics. Int J Biol Sci 3, 179-84.
-
(2007)
Int J Biol Sci
, vol.3
, pp. 179-184
-
-
Lunney, J.K.1
-
22
-
-
4143150883
-
Revised guides for organ sampling and trimming in rats and mice-Part 3. A joint publication of the RITA and NACAD groups
-
Morawietz G., Ruehl-Fehlert C., Kittel B., Bube A., Keane K., Halm S., Heuser A., Hellmann J., Group R., Group N., (2004). Revised guides for organ sampling and trimming in rats and mice-Part 3. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol 55, 433-49.
-
(2004)
Exp Toxicol Pathol
, vol.55
, pp. 433-449
-
-
Morawietz, G.1
Ruehl-Fehlert, C.2
Kittel, B.3
Bube, A.4
Keane, K.5
Halm, S.6
Heuser, A.7
Hellmann, J.8
Group, R.9
Group, N.10
-
23
-
-
79957894124
-
Best practices for evaluation of bone marrow in nonclinical toxicity studies
-
Bone Marrow Working Group of, A. S
-
Reagan W. J., Irizarry-Rovira A., Poitout-Belissent F., Bolliger A. P., Ramaiah S. K., Travlos G., Walker D., Bounous D., Walter G., and Bone Marrow Working Group of, A. S. (2011). Best practices for evaluation of bone marrow in nonclinical toxicity studies. Vet Clin Pathol 40, 119-34.
-
(2011)
Vet Clin Pathol
, vol.40
, pp. 119-134
-
-
Reagan, W.J.1
Irizarry-Rovira, A.2
Poitout-Belissent, F.3
Bolliger, A.P.4
Ramaiah, S.K.5
Travlos, G.6
Walker, D.7
Bounous, D.8
Walter, G.9
-
24
-
-
84876517346
-
Permanent neonatal diabetes in INS(C94Y) transgenic pigs
-
Renner S., Braun-Reichhart C., Blutke A., Herbach N., Emrich D., Streckel E., Wunsch A., Kessler B., Kurome M., Bahr A., Klymiuk N., Krebs S., Puk O., Nagashima H., Graw J., Blum H., Wanke R., Wolf E., (2013). Permanent neonatal diabetes in INS(C94Y) transgenic pigs. Diabetes 62, 1505-11.
-
(2013)
Diabetes
, vol.62
, pp. 1505-1511
-
-
Renner, S.1
Braun-Reichhart, C.2
Blutke, A.3
Herbach, N.4
Emrich, D.5
Streckel, E.6
Wunsch, A.7
Kessler, B.8
Kurome, M.9
Bahr, A.10
Klymiuk, N.11
Krebs, S.12
Puk, O.13
Nagashima, H.14
Graw, J.15
Blum, H.16
Wanke, R.17
Wolf, E.18
-
25
-
-
77951829073
-
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function
-
Renner S., Fehlings C., Herbach N., Hofmann A., von Waldthausen D. C., Kessler B., Ulrichs K., Chodnevskaja I., Moskalenko V., Amselgruber W., Goke B., Pfeifer A., Wanke R., Wolf E., (2010). Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function. Diabetes 59, 1228-38.
-
(2010)
Diabetes
, vol.59
, pp. 1228-1238
-
-
Renner, S.1
Fehlings, C.2
Herbach, N.3
Hofmann, A.4
Von Waldthausen, D.C.5
Kessler, B.6
Ulrichs, K.7
Chodnevskaja, I.8
Moskalenko, V.9
Amselgruber, W.10
Goke, B.11
Pfeifer, A.12
Wanke, R.13
Wolf, E.14
-
26
-
-
84864300391
-
Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced beta-cell mass
-
Renner S., Romisch-Margl W., Prehn C., Krebs S., Adamski J., Goke B., Blum H., Suhre K., Roscher A. A., Wolf E., (2012). Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced beta-cell mass. Diabetes 61, 2166-75.
-
(2012)
Diabetes
, vol.61
, pp. 2166-2175
-
-
Renner, S.1
Romisch-Margl, W.2
Prehn, C.3
Krebs, S.4
Adamski, J.5
Goke, B.6
Blum, H.7
Suhre, K.8
Roscher, A.A.9
Wolf, E.10
-
27
-
-
10744230931
-
Revised guides for organ sampling and trimming in rats and mice - Part 1
-
Ruehl-Fehlert C., Kittel B., Morawietz G., Deslex P., Keenan C., Mahrt C. R., Nolte T., Robinson M., Stuart B. P., Deschl U., Group R., Group N., (2003). Revised guides for organ sampling and trimming in rats and mice-Part 1. Exp Toxicol Pathol 55, 91-106.
-
(2003)
Exp Toxicol Pathol
, vol.55
, pp. 91-106
-
-
Ruehl-Fehlert, C.1
Kittel, B.2
Morawietz, G.3
Deslex, P.4
Keenan, C.5
Mahrt, C.R.6
Nolte, T.7
Robinson, M.8
Stuart, B.P.9
Deschl, U.10
Group, R.11
Group, N.12
-
28
-
-
0014794666
-
A simple method for volumetry of organs in quantitative stereology
-
Scherle W., (1970). A simple method for volumetry of organs in quantitative stereology. Mikroskopie 26, 57-60.
-
(1970)
Mikroskopie
, vol.26
, pp. 57-60
-
-
Scherle, W.1
-
29
-
-
84925010827
-
Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition
-
Streckel E., Braun-Reichhart C., Herbach N., Dahlhoff M., Kessler B., Blutke A., Bahr A., Ubel N., Eddicks M., Ritzmann M., Krebs S., Goke B., Blum H., Wanke R., Wolf E., Renner S., (2015). Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition. J Transl Med 13, 73.
-
(2015)
J Transl Med
, vol.13
, pp. 73
-
-
Streckel, E.1
Braun-Reichhart, C.2
Herbach, N.3
Dahlhoff, M.4
Kessler, B.5
Blutke, A.6
Bahr, A.7
Ubel, N.8
Eddicks, M.9
Ritzmann, M.10
Krebs, S.11
Goke, B.12
Blum, H.13
Wanke, R.14
Wolf, E.15
Renner, S.16
-
30
-
-
84904637119
-
Strategic focus on 3R principles reveals major reductions in the use of animals in pharmaceutical toxicity testing
-
Tornqvist E., Annas A., Granath B., Jalkesten E., Cotgreave I., Oberg M., (2014). Strategic focus on 3R principles reveals major reductions in the use of animals in pharmaceutical toxicity testing. PLoS One 9, e101638.
-
(2014)
PLoS One
, vol.9
, pp. e101638
-
-
Tornqvist, E.1
Annas, A.2
Granath, B.3
Jalkesten, E.4
Cotgreave, I.5
Oberg, M.6
-
31
-
-
84911810734
-
-
Redbook. U.S. Food and Drug Administration. Last modified November 2003
-
Redbook. (2000). IV.B.1 General Guidelines for Designing and Conducting Toxicity Studies. U.S. Food and Drug Administration. Last modified November 2003. http://www.fda.gov/Food/GuidanceRegulation/GuidanceDocumentsRegulatoryInformation/IngredientsAdditivesGRASPackaging/ucm078315.htm.
-
(2000)
IV.B.1 General Guidelines for Designing and Conducting Toxicity Studies
-
-
-
32
-
-
84892406020
-
Genetically engineered pig models for diabetes research
-
Wolf E., Braun-Reichhart C., Streckel E., Renner S., (2014). Genetically engineered pig models for diabetes research. Transgenic Res 23, 27-38.
-
(2014)
Transgenic Res
, vol.23
, pp. 27-38
-
-
Wolf, E.1
Braun-Reichhart, C.2
Streckel, E.3
Renner, S.4
-
33
-
-
84891662454
-
Pig transgenesis by piggyBac transposition in combination with somatic cell nuclear transfer
-
Wu Z., Xu Z., Zou X., Zeng F., Shi J., Liu D., Urschitz J., Moisyadi S., Li Z., (2013). Pig transgenesis by piggyBac transposition in combination with somatic cell nuclear transfer. Transgenic Res 22, 1107-18.
-
(2013)
Transgenic Res
, vol.22
, pp. 1107-1118
-
-
Wu, Z.1
Xu, Z.2
Zou, X.3
Zeng, F.4
Shi, J.5
Liu, D.6
Urschitz, J.7
Moisyadi, S.8
Li, Z.9
-
34
-
-
84895124188
-
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs
-
Wuensch A., Baehr A., Bongoni A. K., Kemter E., Blutke A., Baars W., Haertle S., Zakhartchenko V., Kurome M., Kessler B., Faber C., Abicht J. M., Reichart B., Wanke R., Schwinzer R., Nagashima H., Rieben R., Ayares D., Wolf E., Klymiuk N., (2014). Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs. Transplantation 97, 138-47.
-
(2014)
Transplantation
, vol.97
, pp. 138-147
-
-
Wuensch, A.1
Baehr, A.2
Bongoni, A.K.3
Kemter, E.4
Blutke, A.5
Baars, W.6
Haertle, S.7
Zakhartchenko, V.8
Kurome, M.9
Kessler, B.10
Faber, C.11
Abicht, J.M.12
Reichart, B.13
Wanke, R.14
Schwinzer, R.15
Nagashima, H.16
Rieben, R.17
Ayares, D.18
Wolf, E.19
Klymiuk, N.20
more..
|