STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies

Toxicologic Pathology

Volumn 41, Issue 7, 2013, Pages 1028-1048

  Bolon, Brad ^a   Garman, Robert H ^b   Pardo, Ingrid D ^c   Jensen, Karl ^d   Sills, Robert C ^e   Roulois, Aude ^f   Radovsky, Ann ^g   Bradley, Alys ^h   Andrews Jones, Lydia ⁱ   Butt, Mark ^j   Gumprecht, Laura ^k  

^a OHIO STATE UNIVERSITY   (United States)

^b Consultants in Veterinary Pathology Inc ^*  (United States)

^c PFIZER INC   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^f GLAXOSMITHKLINE   (United Kingdom)

^g WIL RESEARCH LABORATORIES   (United States)

^h CHARLES RIVER LABORATORIES   (United Kingdom)

ⁱ ALLERGAN INC   (United States)

^j Tox Path Specialists LLC   (United States)

^k MERCK RESEARCH LABORATORIES   (United States)

more..

Author keywords

brain; brain weight; CNS; eye; general toxicity study; GLP; nervous system; neuropathology; neurotoxicity; nonclinical toxicity study; PNS; recommended practices; spinal cord

Indexed keywords

ARTICLE; BRAIN; BRAIN CORTEX; BRAIN REGION; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CHOROID PLEXUS; EYE; GOOD LABORATORY PRACTICE; HIPPOCAMPUS; HISTOLOGY; HYPOTHALAMUS; MEDICAL SOCIETY; MEDULLA OBLONGATA; MESENCEPHALON; NERVE; NERVOUS SYSTEM; NEUROPATHOLOGY; NONHUMAN; OLFACTORY BULB; OPTIC NERVE; PERIPHERAL NERVOUS SYSTEM; PONS; PRIORITY JOURNAL; PUTAMEN; SAMPLING; SPINAL CORD; THALAMUS; TOXICITY TESTING;

BRAIN; BRAIN WEIGHT; CNS; EYE; GENERAL TOXICITY STUDY; GLP; NERVOUS SYSTEM; NEUROPATHOLOGY; NEUROTOXICITY; NONCLINICAL TOXICITY STUDY; PNS; RECOMMENDED PRACTICES; SPINAL CORD.;

ANIMALS; EYE; HISTOLOGICAL TECHNIQUES; NERVOUS SYSTEM; ORGAN SIZE; PATHOLOGY; TOXICITY TESTS;

EID: 84884275014     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623312474865     Document Type: Article

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