Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration

Cell

Volumn 165, Issue 1, 2016, Pages 139-152

  Berg, Russell D ^a   Levitte, Steven ^a,b   O'Sullivan, Mary P ^c   O'Leary, Seónadh M ^c   Cambier, C J ^a   Cameron, James ^a   Takaki, Kevin K ^b   Moens, Cecilia B ^d   Tobin, David M ^e   Keane, Joseph ^c,f,g   Ramakrishnan, Lalita ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d Fred Hutchinson Cancer Research Center   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f STANFORD UNIVERSITY   (United States)

^g NOAA EARTH SYSTEM RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; DEXTRAN; FLUORESCENT DYE; POLYPEPTIDE; SMALL NUCLEAR RNA ACTIVATING COMPLEX POLYPEPTIDE 1; TOBACCO SMOKE; UNCLASSIFIED DRUG; SNAPC1 PROTEIN, HUMAN; SNAPC1B PROTEIN, ZEBRAFISH; TRANSCRIPTION FACTOR; ZEBRAFISH PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL MOTILITY; CELL VACUOLE; CONTROLLED STUDY; ENDOCYTOSIS; GAUCHER DISEASE; GRANULOMA; HUMAN; INFECTION SENSITIVITY; LUNG ALVEOLUS MACROPHAGE; LYSOSOME STORAGE DISEASE; MACROPHAGE MIGRATION; MOUSE; MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS; NECROSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; TUBERCULOSIS; ZEBRA FISH; ANIMAL; CYTOLOGY; DISEASE PREDISPOSITION; GENETICS; IMMUNOLOGY; LUNG ALVEOLUS; LYSOSOME; MACROPHAGE; METABOLISM; MYCOBACTERIOSIS; PATHOLOGY; SMOKING; TRANSPORT VESICLE;

ANIMALS; DISEASE SUSCEPTIBILITY; GRANULOMA; LYSOSOMES; MACROPHAGES; MACROPHAGES, ALVEOLAR; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM MARINUM; PULMONARY ALVEOLI; SMOKING; TRANSCRIPTION FACTORS; TRANSPORT VESICLES; TUBERCULOSIS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84961589023     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.02.034     Document Type: Article

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