Equilibrative nucleoside transporter 3 deficiency perturbs lysosome function and macrophage homeostasis

Science

Volumn 335, Issue 6064, 2012, Pages 89-92

  Hsu, Chia Lin ^a   Lin, Weiyu ^a   Seshasayee, Dhaya ^a   Chen, Yung Hsiang ^a   Ding, Xiao ^a   Lin, Zhonghua ^a   Suto, Eric ^a   Huang, Zhiyu ^a   Lee, Wyne P ^a   Park, Hyunjoo ^a   Xu, Min ^a   Sun, Mei ^a   Rangell, Linda ^a   Lutman, Jeff L ^a   Ulufatu, Sheila ^a   Stefanich, Eric ^a   Chalouni, Cecile ^a   Sagolla, Meredith ^a   Diehl, Lauri ^a   Fielder, Paul ^a   Dean, Brian ^a   Balazs, Mercedesz ^a   Martin, Flavius ^a   more..

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR RECEPTOR; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3; NUCLEOSIDE TRANSPORTER; UNCLASSIFIED DRUG;

APOPTOSIS; CELL ORGANELLE; DISEASE; EQUILIBRIUM; HOMEOSTASIS; METABOLITE; MOLECULAR ANALYSIS; MUTATION; PHYSIOLOGY; PUBLIC HEALTH; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; HISTIOCYTOSIS; LYSOSOME; LYSOSOME STORAGE DISEASE; MACROPHAGE; MOUSE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

MUS;

EID: 84855485547     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1213682     Document Type: Article

References (21)

1. S. A. Baldwin et al., Pflugers Arch. 447, 735 (2004).
2. M. Molina-Arcas, F. J. Casado, M. Pastor-Anglada, Curr. Vasc. Pharmacol. 7, 426 (2009).
3. D. G. Russell, B. C. Vanderven, S. Glennie, H. Mwandumba, R. S. Heyderman, Nat. Rev. Immunol. 9, 594 (2009).
4. J. D. Young, S. Y. Yao, L. Sun, C. E. Cass, S. A. Baldwin, Xenobiotica 38, 995 (2008).
5. P. Saftig, J. Klumperman, Nat. Rev. Mol. Cell Biol. 10, 623 (2009).
6. E. B. Vitner, F. M. Platt, A. H. Futerman, J. Biol. Chem. 285, 20423 (2010).
7. G. M. Mancini, A. C. Havelaar, F. W. Verheijen, J. Inherit. Metab. Dis. 23, 278 (2000).
8. A. H. Futerman, G. van Meer, Nat. Rev. Mol. Cell Biol. 5, 554 (2004).
9. T. Tang et al., Nat. Biotechnol. 28, 749 (2010).
10. A. Fraldi et al., EMBO J. 29, 3607 (2010).
11. T. Fukuda et al., Ann. Neurol. 59, 700 (2006).
12. N. Kang et al., J. Biol. Chem. 285, 28343 (2010).
13. B. Poole, S. Ohkuma, J. Cell Biol. 90, 665 (1981).
14. T. G. Douglass et al., Int. Immunopharmacol. 8, 1354 (2008).
15. A. Bartocci et al., Proc. Natl. Acad. Sci. U.S.A. 84, 6179 (1987).
16. P. S. Lee et al., EMBO J. 18, 3616 (1999).
17. E. Avitan-Hersh et al., Am. J. Dermatopathol. 33, 47 (2011).
18. V. Molho-Pessach et al., Am. J. Hum. Genet. 83, 529 (2008).
19. N. V. Morgan et al., PLoS Genet. 6, e1000833 (2010).
20. S. T. Cliffe et al., Hum. Mol. Genet. 18, 2257 (2009).
21. R. Spiegel et al., Eur. J. Med. Genet. 53, 309 (2010).