-
1
-
-
84920585186
-
Efficacy of a tetravalent Dengue vaccine in children in Latin America
-
Villar, L. et al. Efficacy of a tetravalent Dengue vaccine in children in Latin America. N. Engl. J. Med. 372, 113-123 (2015).
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 113-123
-
-
Villar, L.1
-
2
-
-
84908160975
-
CYD14 Study Group Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: A phase 3, randomised, observer-masked, placebo-controlled trial
-
Capeding, M.R., et al., CYD14 Study Group Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial. Lancet 384, 1358-1365 (2014).
-
(2014)
Lancet
, vol.384
, pp. 1358-1365
-
-
Capeding, M.R.1
-
3
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O., Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
4
-
-
84878173821
-
Cytosolic sensing of viruses
-
Goubau, D., Deddouche, S., Reis e Sousa, C. Cytosolic sensing of viruses. Immunity 38, 855-869 (2013).
-
(2013)
Immunity
, vol.38
, pp. 855-869
-
-
Goubau, D.1
Deddouche, S.2
Reise Sousa, C.3
-
5
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Loo, Y.M., Gale, M. Jr. Immune signaling by RIG-I-like receptors. Immunity 34, 680-692 (2011).
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale, Jr.M.2
-
6
-
-
84908192059
-
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5?-diphosphates
-
Goubau, D. et al. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5?-diphosphates. Nature 514, 372-375 (2014).
-
(2014)
Nature
, vol.514
, pp. 372-375
-
-
Goubau, D.1
-
7
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack, M.U. et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446, 916-920 (2007).
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
-
8
-
-
84899957213
-
Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I
-
Peisley, A., Wu, B., Xu, H., Chen, Z.J., Hur, S. Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I. Nature 509, 110-114 (2014).
-
(2014)
Nature
, vol.509
, pp. 110-114
-
-
Peisley, A.1
Wu, B.2
Xu, H.3
Chen, Z.J.4
Hur, S.5
-
9
-
-
77951708374
-
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
-
Zeng, W. et al. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 141, 315-330 (2010).
-
(2010)
Cell
, vol.141
, pp. 315-330
-
-
Zeng, W.1
-
10
-
-
77952503750
-
Peroxisomes are signaling platforms for antiviral innate immunity
-
Dixit, E. et al. Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141, 668-681 (2010).
-
(2010)
Cell
, vol.141
, pp. 668-681
-
-
Dixit, E.1
-
11
-
-
80052281413
-
Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus
-
Horner, S.M., Liu, H.M., Park, H.S., Briley, J., Gale, M. Jr. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc. Natl. Acad. Sci. USA 108, 14590-14595 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14590-14595
-
-
Horner, S.M.1
Liu, H.M.2
Park, H.S.3
Briley, J.4
Gale, Jr.M.5
-
12
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth, R.B., Sun, L., Ea, C.K., Chen, Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682 (2005).
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
13
-
-
84896987305
-
Interferon-stimulated genes: A complex web of host defenses
-
Schneider, W.M., Chevillotte, M.D., Rice, C.M. Interferon-stimulated genes: a complex web of host defenses. Annu. Rev. Immunol. 32, 513-545 (2014).
-
(2014)
Annu. Rev. Immunol
, vol.32
, pp. 513-545
-
-
Schneider, W.M.1
Chevillotte, M.D.2
Rice, C.M.3
-
14
-
-
80053590435
-
Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter
-
Belgnaoui, S.M., Paz, S., Hiscott, J. Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter. Curr. Opin. Immunol. 23, 564-572 (2011).
-
(2011)
Curr. Opin. Immunol
, vol.23
, pp. 564-572
-
-
Belgnaoui, S.M.1
Paz, S.2
Hiscott, J.3
-
15
-
-
84861181618
-
The mitochondrial targeting chaperone 14-3-3ϵ regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity
-
Liu, H.M. et al. The mitochondrial targeting chaperone 14-3-3ϵ regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host Microbe 11, 528-537 (2012).
-
(2012)
Cell Host Microbe
, vol.11
, pp. 528-537
-
-
Liu, H.M.1
-
16
-
-
84919470479
-
Dendritic cells in dengue virus infection: Targets of virus replication and mediators of immunity
-
Schmid, M.A., Diamond, M.S., Harris, E. Dendritic cells in dengue virus infection: targets of virus replication and mediators of immunity. Front. Immunol. 5, 647 (2014).
-
(2014)
Front. Immunol
, vol.5
, pp. 647
-
-
Schmid, M.A.1
Diamond, M.S.2
Harris, E.3
-
17
-
-
84894538775
-
Innate immunity to dengue virus infection and subversion of antiviral responses
-
Green, A.M., Beatty, P.R., Hadjilaou, A., Harris, E. Innate immunity to dengue virus infection and subversion of antiviral responses. J. Mol. Biol. 426, 1148-1160 (2014).
-
(2014)
J. Mol. Biol
, vol.426
, pp. 1148-1160
-
-
Green, A.M.1
Beatty, P.R.2
Hadjilaou, A.3
Harris, E.4
-
18
-
-
66149146738
-
NS5 of dengue virus mediates STAT2 binding and degradation
-
Ashour, J., Laurent-Rolle, M., Shi, P.Y., Garciá-Sastre, A. NS5 of dengue virus mediates STAT2 binding and degradation. J. Virol. 83, 5408-5418 (2009).
-
(2009)
J. Virol
, vol.83
, pp. 5408-5418
-
-
Ashour, J.1
Laurent-Rolle, M.2
Shi, P.Y.3
Garciá-Sastre, A.4
-
19
-
-
84868102239
-
DENV inhibits type i IFN production in infected cells by cleaving human STING
-
Aguirre, S. et al. DENV inhibits type I IFN production in infected cells by cleaving human STING. PLoS Pathog. 8, e1002934 (2012).
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002934
-
-
Aguirre, S.1
-
20
-
-
84864036246
-
Dengue virus targets the adaptor protein MITA to subvert host innate immunity
-
Yu, C.Y. et al. Dengue virus targets the adaptor protein MITA to subvert host innate immunity. PLoS Pathog. 8, e1002780 (2012).
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002780
-
-
Yu, C.Y.1
-
21
-
-
84908416018
-
Coupling of replication and assembly in flaviviruses
-
Apte-Sengupta, S., Sirohi, D., Kuhn, R.J. Coupling of replication and assembly in flaviviruses. Curr. Opin. Virol. 9, 134-142 (2014).
-
(2014)
Curr. Opin. Virol
, vol.9
, pp. 134-142
-
-
Apte-Sengupta, S.1
Sirohi, D.2
Kuhn, R.J.3
-
22
-
-
34247848008
-
The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
-
Miller, S., Kastner, S., Krijnse-Locker, J., Bühler, S., Bartenschlager, R. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 282, 8873-8882 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 8873-8882
-
-
Miller, S.1
Kastner, S.2
Krijnse-Locker, J.3
Bühler, S.4
Bartenschlager, R.5
-
23
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li, X.D., Sun, L., Seth, R.B., Pineda, G., Chen, Z.J. Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc. Natl. Acad. Sci. USA 102, 17717-17722 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
24
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan, E. et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172 (2005).
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
-
25
-
-
0036004555
-
In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates
-
Khumthong, R., Angsuthanasombat, C., Panyim, S., Katzenmeier, G. In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates. J. Biochem. Mol. Biol. 35, 206-212 (2002).
-
(2002)
J. Biochem. Mol. Biol
, vol.35
, pp. 206-212
-
-
Khumthong, R.1
Angsuthanasombat, C.2
Panyim, S.3
Katzenmeier, G.4
-
26
-
-
0025864149
-
Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins
-
Falgout, B., Pethel, M., Zhang, Y.M., Lai, C.J. Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins. J. Virol. 65, 2467-2475 (1991).
-
(1991)
J. Virol
, vol.65
, pp. 2467-2475
-
-
Falgout, B.1
Pethel, M.2
Zhang, Y.M.3
Lai, C.J.4
-
27
-
-
24344460521
-
14-3-3 proteins-an update
-
Mhawech, P. 14-3-3 proteins-an update. Cell Res. 15, 228-236 (2005).
-
(2005)
Cell Res
, vol.15
, pp. 228-236
-
-
Mhawech, P.1
-
28
-
-
0031470652
-
The structural basis for 14-3-3:phosphopeptide binding specificity
-
Yaffe, M.B. et al. The structural basis for 14-3-3:phosphopeptide binding specificity. Cell 91, 961-971 (1997).
-
(1997)
Cell
, vol.91
, pp. 961-971
-
-
Yaffe, M.B.1
-
29
-
-
37349023165
-
Crystal structure of the NS3 protease-helicase from dengue virus
-
Luo, D. et al. Crystal structure of the NS3 protease-helicase from dengue virus. J. Virol. 82, 173-183 (2008).
-
(2008)
J. Virol
, vol.82
, pp. 173-183
-
-
Luo, D.1
-
30
-
-
0030996972
-
Construction of infectious cDNA clones for dengue 2 virus: Strain 16681 and its attenuated vaccine derivative, strain PDK-53
-
Kinney, R.M. et al. Construction of infectious cDNA clones for dengue 2 virus: strain 16681 and its attenuated vaccine derivative, strain PDK-53. Virology 230, 300-308 (1997).
-
(1997)
Virology
, vol.230
, pp. 300-308
-
-
Kinney, R.M.1
-
31
-
-
0034063918
-
Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3
-
Butrapet, S. et al. Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3. J. Virol. 74, 3011-3019 (2000).
-
(2000)
J. Virol
, vol.74
, pp. 3011-3019
-
-
Butrapet, S.1
-
32
-
-
0014340574
-
Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero)
-
Desmyter, J., Melnick, J.L., Rawls, W.E. Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero). J. Virol. 2, 955-961 (1968).
-
(1968)
J. Virol
, vol.2
, pp. 955-961
-
-
Desmyter, J.1
Melnick, J.L.2
Rawls, W.E.3
-
33
-
-
55949131282
-
Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
-
Gack, M.U. et al. Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction. Proc. Natl. Acad. Sci. USA 105, 16743-16748 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16743-16748
-
-
Gack, M.U.1
-
34
-
-
13944253573
-
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase RIG-I
-
Sumpter, R. Jr. et al. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J. Virol. 79, 2689-2699 (2005).
-
(2005)
J. Virol
, vol.79
, pp. 2689-2699
-
-
Sumpter, Jr.R.1
-
35
-
-
2142806767
-
Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization
-
Jessie, K., Fong, M.Y., Devi, S., Lam, S.K., Wong, K.T. Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization. J. Infect. Dis. 189, 1411-1418 (2004).
-
(2004)
J. Infect. Dis
, vol.189
, pp. 1411-1418
-
-
Jessie, K.1
Fong, M.Y.2
Devi, S.3
Lam, S.K.4
Wong, K.T.5
-
36
-
-
77950824984
-
Dengue virus inhibits the production of type i interferon in primary human dendritic cells
-
Rodriguez-Madoz, J.R., Bernal-Rubio, D., Kaminski, D., Boyd, K., Fernandez-Sesma, A. Dengue virus inhibits the production of type I interferon in primary human dendritic cells. J. Virol. 84, 4845-4850 (2010).
-
(2010)
J. Virol
, vol.84
, pp. 4845-4850
-
-
Rodriguez-Madoz, J.R.1
Bernal-Rubio, D.2
Kaminski, D.3
Boyd, K.4
Fernandez-Sesma, A.5
-
37
-
-
0032568665
-
14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove
-
Petosa, C. et al. 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J. Biol. Chem. 273, 16305-16310 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 16305-16310
-
-
Petosa, C.1
-
38
-
-
72249103485
-
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection
-
Shapira, S.D. et al. A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. Cell 139, 1255-1267 (2009).
-
(2009)
Cell
, vol.139
, pp. 1255-1267
-
-
Shapira, S.D.1
-
39
-
-
84859132903
-
IFITM proteins restrict antibody-dependent enhancement of dengue virus infection
-
Chan, Y.K., Huang, I.C., Farzan, M. IFITM proteins restrict antibody-dependent enhancement of dengue virus infection. PLoS One 7, e34508 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e34508
-
-
Chan, Y.K.1
Huang, I.C.2
Farzan, M.3
-
40
-
-
0037142070
-
Efp targets 14-3-3? for proteolysis and promotes breast tumour growth
-
Urano, T. et al. Efp targets 14-3-3? for proteolysis and promotes breast tumour growth. Nature 417, 871-875 (2002).
-
(2002)
Nature
, vol.417
, pp. 871-875
-
-
Urano, T.1
-
41
-
-
84875542059
-
Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling
-
Wies, E. et al. Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling. Immunity 38, 437-449 (2013).
-
(2013)
Immunity
, vol.38
, pp. 437-449
-
-
Wies, E.1
-
42
-
-
0033842515
-
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
-
Lin, R., Génin, P., Mamane, Y., Hiscott, J. Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 20, 6342-6353 (2000).
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 6342-6353
-
-
Lin, R.1
Génin, P.2
Mamane, Y.3
Hiscott, J.4
-
43
-
-
0030838845
-
Ultraspiracle a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter
-
Hatzivassiliou, E., Cardot, P., Zannis, V.I., Mitsialis, S.A. Ultraspiracle, a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter. Biochemistry 36, 9221-9231 (1997).
-
(1997)
Biochemistry
, vol.36
, pp. 9221-9231
-
-
Hatzivassiliou, E.1
Cardot, P.2
Zannis, V.I.3
Mitsialis, S.A.4
-
44
-
-
0033881444
-
Infection of human cells by dengue virus is modulated by different cell types and viral strains
-
Diamond, M.S., Edgil, D., Roberts, T.G., Lu, B., Harris, E. Infection of human cells by dengue virus is modulated by different cell types and viral strains. J. Virol. 74, 7814-7823 (2000).
-
(2000)
J. Virol
, vol.74
, pp. 7814-7823
-
-
Diamond, M.S.1
Edgil, D.2
Roberts, T.G.3
Lu, B.4
Harris, E.5
-
45
-
-
22144488822
-
Flow cytometry-based assay for titrating dengue virus
-
Lambeth, C.R., White, L.J., Johnston, R.E., de Silva, A.M. Flow cytometry-based assay for titrating dengue virus. J. Clin. Microbiol. 43, 3267-3272 (2005).
-
(2005)
J. Clin. Microbiol
, vol.43
, pp. 3267-3272
-
-
Lambeth, C.R.1
White, L.J.2
Johnston, R.E.3
De Silva, A.M.4
|