Influence of surfactants in self-microemulsifying formulations on enhancing oral bioavailability of oxyresveratrol: Studies in Caco-2 cells and in vivo

International Journal of Pharmaceutics

Volumn 498, Issue 1-2, 2016, Pages 294-303

  Sangsen, Yaowaporn ^a   Wiwattanawongsa, Kamonthip ^a   Likhitwitayawuid, Kittisak ^b   Sritularak, Boonchoo ^b   Graidist, Potchanapond ^a   Wiwattanapatapee, Ruedeekorn ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Caco 2 cells; Oral absorption; Oxyresveratrol; Self microemulsifying drug delivery system; SMEDDS; Surfactants

Indexed keywords

LABRASOL; OXYRESVERATROL; POLYPHENOL DERIVATIVE; POLYSORBATE 80; SURFACTANT; UNCLASSIFIED DRUG; EMULSION; PLANT EXTRACT; PUAG-HAAD; STILBENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CACO 2 CELL LINE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DILUTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; STOMACH PH; TIME TO MAXIMUM PLASMA CONCENTRATION; ADMINISTRATION AND DOSAGE; ANIMAL; BIOAVAILABILITY; CACO-2 CELL LINE; CHEMISTRY; EMULSION; HUMAN; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CHEMISTRY, PHARMACEUTICAL; EMULSIONS; HUMANS; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; STILBENES; SURFACE-ACTIVE AGENTS;

EID: 84961365377     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.12.002     Document Type: Article

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