Evaluation of cytotoxicity of surfactants used in self-micro emulsifying drug delivery systems and their effects on paracellular transport in Caco-2 cell monolayer

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 3, 2012, Pages 564-573

  Ujhelyi, Zoltán ^a   Fenyvesi, Ferenc ^a   Váradi, Judit ^a   Fehér, Pálma ^a   Kiss, Tímea ^a   Veszelka, Szilvia ^b   Deli, Mária ^b   Vecsernyés, Miklós ^a   Bácskay, Ildikó ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Caco 2; CMC; Cytotoxicity; Labrasol; Permeability; Polysorbate

Indexed keywords

LABRASOL; LUCIFER YELLOW; MACROGOL; POLYSORBATE; POLYSORBATE 20; POLYSORBATE 60; POLYSORBATE 80; PROPYLENE GLYCOL;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; ELECTRIC RESISTANCE; ESTERIFICATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MONOLAYER CULTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SOLUBILIZATION; SURFACE TENSION; TIGHT JUNCTION;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; HUMANS; INTESTINAL ABSORPTION; POLYETHYLENE GLYCOLS; PROPYLENE GLYCOLS; SURFACE-ACTIVE AGENTS;

EID: 84865438533     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.07.005     Document Type: Article

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