Oral bioavailability enhancement of exemestane from self-microemulsifying drug delivery system (SMEDDS)

AAPS PharmSciTech

Volumn 10, Issue 3, 2009, Pages 906-916

  Singh, Ajeet K ^a   Chaurasiya, Akash ^b   Awasthi, Anshumali ^a   Mishra, Gautam ^a,b   Asati, Dinesh ^c   Khar, Roop K ^b   Mukherjee, Rama ^d  

^a DABUR RESEARCH FOUNDATION   (India)

^b HAMDARD UNIVERSITY   (India)

^c ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^d ARA Healthcare Pvt Ltd   (India)

Author keywords

Bioavailability enhancement; Exemestane; Microemulsion; SMEDDS

Indexed keywords

CASTOR OIL; COSURFACTANT; DIETHYLENE GLYCOL MONOETHYL ETHER; EXEMESTANE; LABRASOL; OIL; SURFACTANT;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DILUTION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MIXTURE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PARTICLE SIZE; RAT; SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM; SINGLE DRUG DOSE; SUSPENSION; THERMOSTABILITY; ZETA POTENTIAL;

ANDROSTADIENES; ANIMALS; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; AROMATASE INHIBITORS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; ELECTROCHEMISTRY; EMULSIONS; EXCIPIENTS; FEMALE; HYDROGEN-ION CONCENTRATION; MASS SPECTROMETRY; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; RATS; RATS, WISTAR; SURFACE-ACTIVE AGENTS; THERMODYNAMICS;

EID: 70449526521     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9281-7     Document Type: Article

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