Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization

Biopolymers

Volumn 106, Issue 1, 2016, Pages 89-100

  Conibear, Anne C ^a,b   Chaousis, Stephanie ^a   Durek, Thomas ^a   Johan Rosengren, K ^a   Craik, David J ^a   Schroeder, Christina I ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

cyclotides; peptide cyclization; peptide drug design; peptides; stability; theta defensins

Indexed keywords

CELL DEATH; CHAINS; CONVERGENCE OF NUMERICAL METHODS; COVALENT BONDS; CYCLIZATION; DRUG DELIVERY; EPITOPES; GRAFTING (CHEMICAL); PROTEINS; STABILIZATION;

BACKBONE CYCLIZATION; CYCLOTIDES; DEFENSINS; NATURALLY OCCURRING; PEPTIDE DRUGS; PHARMACEUTICAL INDUSTRY; PROTEIN-PROTEIN INTERACTIONS; THERAPEUTIC APPLICATION;

PEPTIDES;

ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTYLSERINE; CYCLOTIDE; DEFENSIN; DISULFIDE; EPITOPE; LYP1 PEPTIDE; PEPTIDE; SURVIVIN; UNCLASSIFIED DRUG;

ARTICLE; CLICK CHEMISTRY; CONTROLLED STUDY; CYCLIZATION; DISULFIDE BOND; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; SERUM; SOLID; TUMOR CELL; AMINO ACID SEQUENCE; BLOOD; CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TUMOR CELL LINE;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CYCLIZATION; EPITOPES; HUMANS; PEPTIDES; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

EID: 84961316062     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22767     Document Type: Article

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