Lycopene and Apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-Carotene-9',10'- oxygenase knockout male mice

Journal of Nutrition

Volumn 145, Issue 2, 2015, Pages 268-276

  Ip, Blanche C ^a   Liu, Chun ^a   Lichtenstein, Alice H ^a,b   Von Lintig, Johannes ^c   Wang, Xiang Dong ^a  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carotenoid metabolism; Hepatic cholesterol; Lipid metabolism; Mesenteric adipose tissue; Mitochondrial uncoupling; Nonalcoholic fatty liver disease; Obesity; Plasma lipids; PPAR; Sirtuin 1

Indexed keywords

ABC TRANSPORTER G5; ACETYL COENZYME A CARBOXYLASE; APO 10' LYCOPENOIC ACID; BETA CAROTENE 9',10' OXYGENASE; CARRIER PROTEIN; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIPOPROTEIN LIPASE; LIVER PROTECTIVE AGENT; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; LYCOPENE; OXYGENASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SATURATED FATTY ACID; SIRTUIN 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3; ABC TRANSPORTER; ACYL COENZYME A DESATURASE; APO-10'-LYCOPENOIC ACID; BCO2 PROTEIN, MOUSE; BIOLOGICAL MARKER; CAROTENOID; DIOXYGENASE; FATTY ACID; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE; UNSATURATED FATTY ACID;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DEACETYLATION; DIET SUPPLEMENTATION; DISEASE SEVERITY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FAT INTAKE; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY LIVER; FEMALE; GENE EXPRESSION; KNOCKOUT MOUSE; LIPOGENESIS; LIVER PROTECTION; LIVER WEIGHT; MALE; MESENTERY; MOLECULAR MECHANICS; MOUSE; MURINE MODEL; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PROTEIN EXPRESSION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; ANIMAL; BLOOD; DRUG EFFECTS; GENETICS; LIPID DIET; LIVER; METABOLISM; PHOSPHORYLATION;

MUS;

ACETYL-COA CARBOXYLASE; ADIPOSE TISSUE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOMARKERS; CAROTENOIDS; CHOLESTEROL; DIET, HIGH-FAT; DIOXYGENASES; FATTY ACIDS; FATTY ACIDS, UNSATURATED; FATTY LIVER; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; LIVER; MALE; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PPAR ALPHA; PPAR GAMMA; SIGNAL TRANSDUCTION; SIRTUIN 1; STEAROYL-COA DESATURASE; TRIGLYCERIDES; UP-REGULATION;

EID: 84961291237     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.200238     Document Type: Article

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