Lycopene metabolite, apo-10′-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice

Cancer Prevention Research

Volumn 6, Issue 12, 2013, Pages 1304-1316

  Ip, Blanche C ^a,b   Hu, Kang Quan ^a   Liu, Chun ^a   Smith, Donald E ^a   Obin, Martin S ^a,b   Ausman, Lynne M ^a,b   Wang, Xiang Dong ^a,b  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; APO 10' LYCOPENOIC ACID; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DIETHYLNITROSAMINE; GLUCOSE; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LYCOPENE; PROTEIN KINASE B; PROTEIN P21; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIRTUIN 1; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEACETYLATION; DIET SUPPLEMENTATION; ENZYME ACTIVATION; FATTY LIVER; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEPATITIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN TOLERANCE TEST; LIPID DIET; LIVER CARCINOGENESIS; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR VOLUME;

ALKYLATING AGENTS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CAROTENOIDS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN D1; DIET, HIGH-FAT; DIETHYLNITROSAMINE; FATTY ACIDS, UNSATURATED; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INFLAMMATION; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84890493012     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-13-0178     Document Type: Article

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