Chemoradiation therapy using cyclopamine-loaded liquid-lipid nanoparticles and lutetium-177-labeled core-crosslinked polymeric micelles

Journal of Controlled Release

Volumn 202, Issue , 2015, Pages 40-48

  You, Jian ^a,c   Zhao, Jun ^a   Wen, Xiaoxia ^a   Wu, Chunhui ^a,d   Huang, Qian ^a   Guan, Fada ^a   Wu, Richard ^a   Liang, Dong ^b   Li, Chun ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b TEXAS SOUTHERN UNIVERSITY   (United States)

^c ZHEJIANG UNIVERSITY   (China)

^d UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Cyclopamine; Lipid emulsion; Lutetium 177; Micelles; Radiation enhancement

Indexed keywords

CELL CULTURE; CELLS; CYTOLOGY; DISEASES; DRUG DELIVERY; EMULSIFICATION; LIQUIDS; LUTETIUM; MAMMALS; MICELLES; NANOPARTICLES; POLYMERS; TUMORS;

CHEMORADIATION THERAPIES; CROSS-LINKED POLYMERIC MICELLES; CYCLOPAMINE; LIPID EMULSIONS; PANCREATIC ADENOCARCINOMA; PHARMACOKINETIC PROPERTIES; RADIATION ENHANCEMENT; SYSTEMIC ADMINISTRATION;

RADIOTHERAPY;

CYCLOPAMINE; LUTETIUM 177; NANOPARTICLE; ANTINEOPLASTIC AGENT; LUTETIUM; RADIOISOTOPE; VERATRUM ALKALOID;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BREAST CANCER; CANCER SURVIVAL; CHEMORADIOTHERAPY; CLONOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DRUG CLEARANCE; DRUG DISTRIBUTION; HUMAN; HUMAN CELL; MAXIMUM PLASMA CONCENTRATION; MICELLE; MONOTHERAPY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MULTIMODALITY CANCER THERAPY; NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMORADIOTHERAPY; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LUTETIUM; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; PANCREATIC NEOPLASMS; RADIOISOTOPES; TISSUE DISTRIBUTION; TUMOR BURDEN; VERATRUM ALKALOIDS;

EID: 84961291046     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.01.031     Document Type: Article

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