메뉴 건너뛰기




Volumn 7, Issue , 2016, Pages 27-32

Carbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1

Author keywords

Carbohydrates; Glucagon like peptide 1; Glucose dependent insulinotropic polypeptide

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; FRUCTOSE; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLUCOSE TRANSPORTER 5; MONOSACCHARIDE; SODIUM GLUCOSE COTRANSPORTER 1; SWEETENING AGENT; CARBOHYDRATE DIET; INCRETIN;

EID: 84961266473     PISSN: 20401116     EISSN: 20401124     Source Type: Journal    
DOI: 10.1111/jdi.12449     Document Type: Article
Times cited : (21)

References (50)
  • 1
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007; 132: 2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 2
    • 84878360808 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: incretin actions beyond the pancreas
    • Seino Y, Yabe D. Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: incretin actions beyond the pancreas. J Diabetes Investig 2013; 4: 108-130.
    • (2013) J Diabetes Investig , vol.4 , pp. 108-130
    • Seino, Y.1    Yabe, D.2
  • 3
    • 0028838030 scopus 로고
    • Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients
    • Herrmann C, Göke R, Richter G, et al. Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients. Digestion 1995; 56: 117-126.
    • (1995) Digestion , vol.56 , pp. 117-126
    • Herrmann, C.1    Göke, R.2    Richter, G.3
  • 4
    • 0032982267 scopus 로고    scopus 로고
    • Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion
    • Rocca AS, Brubaker PL. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology 1999; 140: 1687-1694.
    • (1999) Endocrinology , vol.140 , pp. 1687-1694
    • Rocca, A.S.1    Brubaker, P.L.2
  • 5
    • 0016190840 scopus 로고
    • Gastric inhibitory polypeptide (GIP) stimulation by oral glucose in man
    • Cataland S, Crockett SE, Brown JC, et al. Gastric inhibitory polypeptide (GIP) stimulation by oral glucose in man. J Clin Endocrinol Metab 1974; 39: 223-228.
    • (1974) J Clin Endocrinol Metab , vol.39 , pp. 223-228
    • Cataland, S.1    Crockett, S.E.2    Brown, J.C.3
  • 6
    • 84867820927 scopus 로고    scopus 로고
    • Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion
    • Sakamoto E, Seino Y, Fukami A, et al. Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion. J Diabetes Investig 2012; 3: 432-440.
    • (2012) J Diabetes Investig , vol.3 , pp. 432-440
    • Sakamoto, E.1    Seino, Y.2    Fukami, A.3
  • 7
    • 84873025669 scopus 로고    scopus 로고
    • Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides
    • Fukami A, Seino Y, Ozaki N, et al. Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides. Diabetes 2013; 62: 510-518.
    • (2013) Diabetes , vol.62 , pp. 510-518
    • Fukami, A.1    Seino, Y.2    Ozaki, N.3
  • 8
    • 35448995622 scopus 로고    scopus 로고
    • T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1
    • Margolskee RF, Dyer J, Kokrashvili Z, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci U S A 2007; 104: 15075-15080.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15075-15080
    • Margolskee, R.F.1    Dyer, J.2    Kokrashvili, Z.3
  • 9
    • 0035855939 scopus 로고    scopus 로고
    • Receptors and transduction in taste
    • Lindemann B. Receptors and transduction in taste. Nature 2001; 413: 219-225.
    • (2001) Nature , vol.413 , pp. 219-225
    • Lindemann, B.1
  • 10
    • 84905694169 scopus 로고    scopus 로고
    • KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state
    • Ogata H, Seino Y, Harada N, et al. KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state. J Endocrinol 2014; 222: 191-200.
    • (2014) J Endocrinol , vol.222 , pp. 191-200
    • Ogata, H.1    Seino, Y.2    Harada, N.3
  • 11
    • 64749083079 scopus 로고    scopus 로고
    • Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo
    • Fujita Y, Wideman RD, Speck M, et al. Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. Am J Physiol Endocrinol Metab 2009; 296: E473-E479.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E473-E479
    • Fujita, Y.1    Wideman, R.D.2    Speck, M.3
  • 12
    • 67149121867 scopus 로고    scopus 로고
    • Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects
    • Ma J, Bellon M, Wishart JM, et al. Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects. Am J Physiol Gastrointest Liver Physiol 2009; 296: G735-G739.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , pp. G735-G739
    • Ma, J.1    Bellon, M.2    Wishart, J.M.3
  • 13
    • 35448986920 scopus 로고    scopus 로고
    • Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
    • Jang H, Kokrashvili Z, Theodorakis MJ, et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A 2007; 104: 15069-15074.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15069-15074
    • Jang, H.1    Kokrashvili, Z.2    Theodorakis, M.J.3
  • 14
    • 58149464981 scopus 로고    scopus 로고
    • Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells
    • Parker HE, Habib AM, Rogers GJ, et al. Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells. Diabetologia 2009; 52: 289-298.
    • (2009) Diabetologia , vol.52 , pp. 289-298
    • Parker, H.E.1    Habib, A.M.2    Rogers, G.J.3
  • 15
    • 56449093424 scopus 로고    scopus 로고
    • Glucose sensing in L cells: a primary cell study
    • Reimann F, Habib AM, Tolhurst G, et al. Glucose sensing in L cells: a primary cell study. Cell Metab 2008; 8: 532-539.
    • (2008) Cell Metab , vol.8 , pp. 532-539
    • Reimann, F.1    Habib, A.M.2    Tolhurst, G.3
  • 16
    • 84921897932 scopus 로고    scopus 로고
    • Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine
    • Kuhre RE, Frost CR, Svendsen B, et al. Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine. Diabetes 2015; 64: 370-382.
    • (2015) Diabetes , vol.64 , pp. 370-382
    • Kuhre, R.E.1    Frost, C.R.2    Svendsen, B.3
  • 17
    • 84940609646 scopus 로고    scopus 로고
    • Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: role of adenosine triphosphate-sensitive K + channels
    • Seino Y, Ogata H, Maekawa R, et al. Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: role of adenosine triphosphate-sensitive K + channels. J Diabetes Investig 2015; 6: 522-526.
    • (2015) J Diabetes Investig , vol.6 , pp. 522-526
    • Seino, Y.1    Ogata, H.2    Maekawa, R.3
  • 19
    • 0020954875 scopus 로고
    • Gastric inhibitory polypeptide (GIP) release by actively transported, structurally similar carbohydrates
    • Available from:.
    • Sirinek KR, Levine BA, O'Dorisio TM, et al. Gastric inhibitory polypeptide (GIP) release by actively transported, structurally similar carbohydrates. Proc Soc Exp Biol Med 1983; 173: 379-385. Available from: http://www.ncbi.nlm.nih.gov/pubmed/6867011.
    • (1983) Proc Soc Exp Biol Med , vol.173 , pp. 379-385
    • Sirinek, K.R.1    Levine, B.A.2    O'Dorisio, T.M.3
  • 20
    • 0024420553 scopus 로고
    • Stimulation of gastric inhibitory polypeptide release in ob/ob mice by oral administration of sugars and their analogues
    • Available from:.
    • Flatt PR, Kwasowski P, Bailey CJ. Stimulation of gastric inhibitory polypeptide release in ob/ob mice by oral administration of sugars and their analogues. J Nutr 1989; 119: 1300-1303. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2795243.
    • (1989) J Nutr , vol.119 , pp. 1300-1303
    • Flatt, P.R.1    Kwasowski, P.2    Bailey, C.J.3
  • 21
    • 0141532690 scopus 로고    scopus 로고
    • A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line
    • Available from:.
    • Gribble FM, Williams L, Simpson AK, et al. A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line. Diabetes 2003; 52: 1147-1154. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12716745.
    • (2003) Diabetes , vol.52 , pp. 1147-1154
    • Gribble, F.M.1    Williams, L.2    Simpson, A.K.3
  • 22
    • 84857426294 scopus 로고    scopus 로고
    • Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion
    • Kyriazis GA, Soundarapandian MM, Tyrberg B. Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion. Proc Natl Acad Sci U S A 2012; 109: E524-E532.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E524-E532
    • Kyriazis, G.A.1    Soundarapandian, M.M.2    Tyrberg, B.3
  • 23
    • 0035644193 scopus 로고    scopus 로고
    • Dietary and developmental regulation of intestinal sugar transport
    • Available from:.
    • Ferraris RP. Dietary and developmental regulation of intestinal sugar transport. Biochem J 2001(Pt 2); 360: 265-276. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1222226&tool=pmcentrez&rendertype=abstract.
    • (2001) Biochem J , vol.360 , pp. 265-276
    • Ferraris, R.P.1
  • 24
    • 79951725107 scopus 로고    scopus 로고
    • Comparative expression of hexose transporters (SGLT1, GLUT1, GLUT2 and GLUT5) throughout the mouse gastrointestinal tract
    • Yoshikawa T, Inoue R, Matsumoto M, et al. Comparative expression of hexose transporters (SGLT1, GLUT1, GLUT2 and GLUT5) throughout the mouse gastrointestinal tract. Histochem Cell Biol 2011; 135: 183-194.
    • (2011) Histochem Cell Biol , vol.135 , pp. 183-194
    • Yoshikawa, T.1    Inoue, R.2    Matsumoto, M.3
  • 25
    • 0032756827 scopus 로고    scopus 로고
    • Immunocytochemical evidence for a paracrine interaction between GIP and GLP-1-producing cells in canine small intestine
    • Available from:.
    • Damholt AB, Kofod H, Buchan AM. Immunocytochemical evidence for a paracrine interaction between GIP and GLP-1-producing cells in canine small intestine. Cell Tissue Res 1999; 298: 287-293. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10571117.
    • (1999) Cell Tissue Res , vol.298 , pp. 287-293
    • Damholt, A.B.1    Kofod, H.2    Buchan, A.M.3
  • 26
    • 84866065884 scopus 로고    scopus 로고
    • Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion
    • Parker HE, Adriaenssens A, Rogers G, et al. Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion. Diabetologia 2012; 55(9): 2445-55. doi:10.1007/s00125-012-2585-2.
    • (2012) Diabetologia , vol.55 , Issue.9 , pp. 2445-2455
    • Parker, H.E.1    Adriaenssens, A.2    Rogers, G.3
  • 27
    • 72249113386 scopus 로고    scopus 로고
    • Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice
    • Moriya R, Shirakura T, Ito J, et al. Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice. Am J Physiol Endocrinol Metab 2009; 297: E1358-E1365.
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. E1358-E1365
    • Moriya, R.1    Shirakura, T.2    Ito, J.3
  • 28
    • 84555186977 scopus 로고    scopus 로고
    • Na(+)-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion
    • Gorboulev V, Schürmann A, Vallon V, et al. Na(+)-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes 2012; 61: 187-196.
    • (2012) Diabetes , vol.61 , pp. 187-196
    • Gorboulev, V.1    Schürmann, A.2    Vallon, V.3
  • 29
    • 84876519168 scopus 로고    scopus 로고
    • LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose
    • Powell DR, Smith M, Greer J, et al. LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose. J Pharmacol Exp Ther 2013; 345: 250-259.
    • (2013) J Pharmacol Exp Ther , vol.345 , pp. 250-259
    • Powell, D.R.1    Smith, M.2    Greer, J.3
  • 30
    • 0018671959 scopus 로고
    • Metabolic effects of glucose, mannose, galactose, and fructose in man
    • Available from:.
    • Ganda OP, Soeldner JS, Gleason RE, et al. Metabolic effects of glucose, mannose, galactose, and fructose in man. J Clin Endocrinol Metab 1979; 49: 616-622. Available from: http://www.ncbi.nlm.nih.gov/pubmed/479351.
    • (1979) J Clin Endocrinol Metab , vol.49 , pp. 616-622
    • Ganda, O.P.1    Soeldner, J.S.2    Gleason, R.E.3
  • 31
    • 0030898014 scopus 로고    scopus 로고
    • Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum
    • Available from:.
    • Ritzel U, Fromme A, Ottleben M, et al. Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum. Acta Diabetol 1997; 34: 18-21. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9134052.
    • (1997) Acta Diabetol , vol.34 , pp. 18-21
    • Ritzel, U.1    Fromme, A.2    Ottleben, M.3
  • 32
    • 35948941910 scopus 로고    scopus 로고
    • The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion
    • El-Ouaghlidi A, Rehring E, Holst JJ, et al. The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion. J Clin Endocrinol Metab 2007; 92: 4165-4171.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4165-4171
    • El-Ouaghlidi, A.1    Rehring, E.2    Holst, J.J.3
  • 33
    • 81255157890 scopus 로고    scopus 로고
    • Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus
    • Stephens JW, Bodvarsdottir TB, Wareham K, et al. Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. Diabetes Res Clin Pract 2011; 94: 199-206.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 199-206
    • Stephens, J.W.1    Bodvarsdottir, T.B.2    Wareham, K.3
  • 34
    • 33746686369 scopus 로고    scopus 로고
    • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
    • Pearson ER, Flechtner I, Njølstad PR, et al. Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. N Engl J Med 2006; 355: 467-477.
    • (2006) N Engl J Med , vol.355 , pp. 467-477
    • Pearson, E.R.1    Flechtner, I.2    Njølstad, P.R.3
  • 35
    • 57249095765 scopus 로고    scopus 로고
    • Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor
    • Murphy R, Tura A, Clark PM, et al. Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor. Diabetologia 2009; 52: 154-159.
    • (2009) Diabetologia , vol.52 , pp. 154-159
    • Murphy, R.1    Tura, A.2    Clark, P.M.3
  • 36
    • 80052698443 scopus 로고    scopus 로고
    • Insulin modulates glucose-dependent insulinotropic polypeptide (GIP) secretion from enteroendocrine K cells in rats
    • Irwin N, Francis JM, Flatt PR. Insulin modulates glucose-dependent insulinotropic polypeptide (GIP) secretion from enteroendocrine K cells in rats. Biol Chem 2011; 392: 909-918.
    • (2011) Biol Chem , vol.392 , pp. 909-918
    • Irwin, N.1    Francis, J.M.2    Flatt, P.R.3
  • 37
    • 84862560443 scopus 로고    scopus 로고
    • The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine
    • Mace OJ, Schindler M, Patel S. The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. J Physiol 2012; 590(Pt 12): 2917-2936.
    • (2012) J Physiol , vol.590 , pp. 2917-2936
    • Mace, O.J.1    Schindler, M.2    Patel, S.3
  • 38
    • 34548297531 scopus 로고    scopus 로고
    • GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion
    • Cani PD, Holst JJ, Drucker DJ, et al. GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion. Mol Cell Endocrinol 2007; 276: 18-23.
    • (2007) Mol Cell Endocrinol , vol.276 , pp. 18-23
    • Cani, P.D.1    Holst, J.J.2    Drucker, D.J.3
  • 39
    • 84865147548 scopus 로고    scopus 로고
    • Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery
    • Geraedts MC, Takahashi T, Vigues S, et al. Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery. Am J Physiol Endocrinol Metab 2012; 303: E464-E474.
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E464-E474
    • Geraedts, M.C.1    Takahashi, T.2    Vigues, S.3
  • 40
    • 0141630107 scopus 로고    scopus 로고
    • Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice
    • Available from:.
    • Miki T, Nagashima K, Tashiro F, et al. Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. Proc Natl Acad Sci U S A 1998; 95: 10402-10406. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=27906&tool=pmcentrez&rendertype=abstract.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10402-10406
    • Miki, T.1    Nagashima, K.2    Tashiro, F.3
  • 41
    • 15944419821 scopus 로고    scopus 로고
    • Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility
    • Available from:.
    • Miki T, Minami K, Shinozaki H, et al. Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility. Diabetes 2005; 54: 1056-1063. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15793244.
    • (2005) Diabetes , vol.54 , pp. 1056-1063
    • Miki, T.1    Minami, K.2    Shinozaki, H.3
  • 42
    • 84924811717 scopus 로고    scopus 로고
    • Distinct action of the -glucosidase inhibitor miglitol on SGLT3, enteroendocrine cells, and GLP1 secretion
    • Lee EY, Kaneko S, Jutabha P, et al. Distinct action of the -glucosidase inhibitor miglitol on SGLT3, enteroendocrine cells, and GLP1 secretion. J Endocrinol 2014; 224: 205-214.
    • (2014) J Endocrinol , vol.224 , pp. 205-214
    • Lee, E.Y.1    Kaneko, S.2    Jutabha, P.3
  • 43
    • 79551593329 scopus 로고    scopus 로고
    • The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas
    • Prasadan K, Koizumi M, Tulachan S, et al. The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas. Diabetes 2011; 60: 548-554.
    • (2011) Diabetes , vol.60 , pp. 548-554
    • Prasadan, K.1    Koizumi, M.2    Tulachan, S.3
  • 44
    • 77951675095 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion
    • Fujita Y, Wideman RD, Asadi A, et al. Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion. Gastroenterology 2010; 138: 1966-1975.
    • (2010) Gastroenterology , vol.138 , pp. 1966-1975
    • Fujita, Y.1    Wideman, R.D.2    Asadi, A.3
  • 45
    • 73249117478 scopus 로고    scopus 로고
    • Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet (alpha)-cells but not of intestinal L-cells
    • Hayashi Y, Yamamoto M, Mizoguchi H, et al. Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet (alpha)-cells but not of intestinal L-cells. Mol Endocrinol 2009; 23: 1990-1999.
    • (2009) Mol Endocrinol , vol.23 , pp. 1990-1999
    • Hayashi, Y.1    Yamamoto, M.2    Mizoguchi, H.3
  • 46
    • 79961202907 scopus 로고    scopus 로고
    • Metabolic impact of glucagon deficiency
    • Hayashi Y. Metabolic impact of glucagon deficiency. Diabetes Obes Metab 2011; 13(Suppl. 1): 151-157.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 151-157
    • Hayashi, Y.1
  • 47
    • 81255157471 scopus 로고    scopus 로고
    • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
    • Ellingsgaard H, Hauselmann I, Schuler B, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med 2011; 17: 1481-1489.
    • (2011) Nat Med , vol.17 , pp. 1481-1489
    • Ellingsgaard, H.1    Hauselmann, I.2    Schuler, B.3
  • 48
    • 0034129091 scopus 로고    scopus 로고
    • Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats
    • Nie Y, Nakashima M, Brubaker PL, et al. Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats. J Clin Invest 2000; 105: 955-965.
    • (2000) J Clin Invest , vol.105 , pp. 955-965
    • Nie, Y.1    Nakashima, M.2    Brubaker, P.L.3
  • 49
    • 84905576401 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes
    • Omar BA, Liehua L, Yamada Y, et al. Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes. Diabetologia 2014; 57: 1876-1883.
    • (2014) Diabetologia , vol.57 , pp. 1876-1883
    • Omar, B.A.1    Liehua, L.2    Yamada, Y.3
  • 50
    • 84937763347 scopus 로고    scopus 로고
    • Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
    • Bonner C, Kerr-Conte J, Gmyr V, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med 2015; 21: 512-517.
    • (2015) Nat Med , vol.21 , pp. 512-517
    • Bonner, C.1    Kerr-Conte, J.2    Gmyr, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.